Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | DNA_REPLICATION_REACTOME |
| Enrichment Score (ES) | -0.46830606 |
| Normalized Enrichment Score (NES) | -1.4004649 |
| Nominal p-value | 0.0988764 |
| FDR q-value | 0.47787765 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 1021 | 0.119 | 0.0034 | No |
| 2 | UBC | UBC Entrez, Source | ubiquitin C | 3136 | 0.046 | -0.1247 | No |
| 3 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 3699 | 0.035 | -0.1433 | No |
| 4 | ORC4L | ORC4L Entrez, Source | origin recognition complex, subunit 4-like (yeast) | 4080 | 0.029 | -0.1524 | No |
| 5 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 4310 | 0.025 | -0.1527 | No |
| 6 | UBB | UBB Entrez, Source | ubiquitin B | 4379 | 0.024 | -0.1417 | No |
| 7 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5938 | 0.003 | -0.2567 | No |
| 8 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 6442 | -0.004 | -0.2920 | No |
| 9 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 6476 | -0.004 | -0.2917 | No |
| 10 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7792 | -0.021 | -0.3766 | No |
| 11 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 9014 | -0.038 | -0.4430 | Yes |
| 12 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 9276 | -0.041 | -0.4349 | Yes |
| 13 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 9651 | -0.048 | -0.4309 | Yes |
| 14 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 10094 | -0.055 | -0.4273 | Yes |
| 15 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 10103 | -0.055 | -0.3910 | Yes |
| 16 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10927 | -0.072 | -0.4048 | Yes |
| 17 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 10979 | -0.073 | -0.3599 | Yes |
| 18 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 11274 | -0.081 | -0.3280 | Yes |
| 19 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 11368 | -0.083 | -0.2793 | Yes |
| 20 | UBA52 | UBA52 Entrez, Source | ubiquitin A-52 residue ribosomal protein fusion product 1 | 11752 | -0.094 | -0.2453 | Yes |
| 21 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12141 | -0.109 | -0.2015 | Yes |
| 22 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12174 | -0.110 | -0.1299 | Yes |
| 23 | ORC3L | ORC3L Entrez, Source | origin recognition complex, subunit 3-like (yeast) | 12175 | -0.110 | -0.0559 | Yes |
| 24 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13114 | -0.214 | 0.0171 | Yes |
