Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | ELECTRON_CARRIER_ACTIVITY |
| Enrichment Score (ES) | -0.36032054 |
| Normalized Enrichment Score (NES) | -1.2331166 |
| Nominal p-value | 0.1550926 |
| FDR q-value | 0.619342 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CYBA | CYBA Entrez, Source | cytochrome b-245, alpha polypeptide | 353 | 0.229 | 0.0308 | No |
| 2 | POR | POR Entrez, Source | P450 (cytochrome) oxidoreductase | 421 | 0.204 | 0.0770 | No |
| 3 | DEGS1 | DEGS1 Entrez, Source | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) | 1169 | 0.111 | 0.0487 | No |
| 4 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 1245 | 0.108 | 0.0700 | No |
| 5 | DMGDH | DMGDH Entrez, Source | dimethylglycine dehydrogenase | 1276 | 0.105 | 0.0942 | No |
| 6 | ETFDH | ETFDH Entrez, Source | electron-transferring-flavoprotein dehydrogenase | 1310 | 0.104 | 0.1177 | No |
| 7 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2059 | 0.071 | 0.0792 | No |
| 8 | HMOX2 | HMOX2 Entrez, Source | heme oxygenase (decycling) 2 | 2775 | 0.053 | 0.0388 | No |
| 9 | CYB5R2 | CYB5R2 Entrez, Source | cytochrome b5 reductase 2 | 2875 | 0.051 | 0.0442 | No |
| 10 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 3372 | 0.041 | 0.0172 | No |
| 11 | CYB5R4 | CYB5R4 Entrez, Source | cytochrome b5 reductase 4 | 3970 | 0.031 | -0.0201 | No |
| 12 | NOX4 | NOX4 Entrez, Source | NADPH oxidase 4 | 4346 | 0.025 | -0.0421 | No |
| 13 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 4664 | 0.020 | -0.0609 | No |
| 14 | ETFA | ETFA Entrez, Source | electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) | 4825 | 0.018 | -0.0684 | No |
| 15 | NDUFS2 | NDUFS2 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 5319 | 0.011 | -0.1028 | No |
| 16 | PHGDH | PHGDH Entrez, Source | phosphoglycerate dehydrogenase | 5695 | 0.006 | -0.1296 | No |
| 17 | FDXR | FDXR Entrez, Source | ferredoxin reductase | 6479 | -0.004 | -0.1875 | No |
| 18 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 6558 | -0.005 | -0.1920 | No |
| 19 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 6671 | -0.007 | -0.1988 | No |
| 20 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 6734 | -0.007 | -0.2016 | No |
| 21 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 7060 | -0.011 | -0.2232 | No |
| 22 | NDUFS4 | NDUFS4 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 7499 | -0.017 | -0.2519 | No |
| 23 | MTRR | MTRR Entrez, Source | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 7592 | -0.018 | -0.2543 | No |
| 24 | CYB5R3 | CYB5R3 Entrez, Source | cytochrome b5 reductase 3 | 7686 | -0.019 | -0.2565 | No |
| 25 | TXNRD2 | TXNRD2 Entrez, Source | thioredoxin reductase 2 | 8114 | -0.025 | -0.2823 | No |
| 26 | ETFB | ETFB Entrez, Source | electron-transfer-flavoprotein, beta polypeptide | 8173 | -0.026 | -0.2801 | No |
| 27 | COX5A | COX5A Entrez, Source | cytochrome c oxidase subunit Va | 8314 | -0.028 | -0.2836 | No |
| 28 | CYP1A2 | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 8681 | -0.033 | -0.3028 | No |
| 29 | SARDH | SARDH Entrez, Source | sarcosine dehydrogenase | 8785 | -0.035 | -0.3018 | No |
| 30 | GPX2 | GPX2 Entrez, Source | glutathione peroxidase 2 (gastrointestinal) | 8829 | -0.035 | -0.2962 | No |
| 31 | NQO1 | NQO1 Entrez, Source | NAD(P)H dehydrogenase, quinone 1 | 9220 | -0.040 | -0.3154 | No |
| 32 | FDX1 | FDX1 Entrez, Source | ferredoxin 1 | 9287 | -0.042 | -0.3100 | No |
| 33 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 9857 | -0.051 | -0.3400 | No |
| 34 | NDUFA9 | NDUFA9 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 9915 | -0.052 | -0.3312 | No |
| 35 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 10295 | -0.058 | -0.3451 | Yes |
| 36 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 10320 | -0.059 | -0.3321 | Yes |
| 37 | NCF1 | NCF1 Entrez, Source | neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) | 10343 | -0.059 | -0.3189 | Yes |
| 38 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 10672 | -0.066 | -0.3271 | Yes |
| 39 | GSR | GSR Entrez, Source | glutathione reductase | 10698 | -0.066 | -0.3124 | Yes |
| 40 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 10870 | -0.070 | -0.3077 | Yes |
| 41 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 11025 | -0.074 | -0.3008 | Yes |
| 42 | NDUFS7 | NDUFS7 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 11060 | -0.075 | -0.2846 | Yes |
| 43 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 12067 | -0.106 | -0.3338 | Yes |
| 44 | AKR7A2 | AKR7A2 Entrez, Source | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 12358 | -0.119 | -0.3258 | Yes |
| 45 | HAAO | HAAO Entrez, Source | 3-hydroxyanthranilate 3,4-dioxygenase | 12465 | -0.125 | -0.3025 | Yes |
| 46 | AKR7A3 | AKR7A3 Entrez, Source | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 12850 | -0.159 | -0.2916 | Yes |
| 47 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 12882 | -0.162 | -0.2532 | Yes |
| 48 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 12915 | -0.167 | -0.2137 | Yes |
| 49 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 12962 | -0.175 | -0.1734 | Yes |
| 50 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 12987 | -0.180 | -0.1299 | Yes |
| 51 | NQO2 | NQO2 Entrez, Source | NAD(P)H dehydrogenase, quinone 2 | 13091 | -0.207 | -0.0857 | Yes |
| 52 | KMO | KMO Entrez, Source | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 13304 | -0.417 | 0.0029 | Yes |
