Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | ELECTRON_TRANSPORTER_ACTIVITY |
| Enrichment Score (ES) | -0.4634769 |
| Normalized Enrichment Score (NES) | -1.6997826 |
| Nominal p-value | 0.0023923444 |
| FDR q-value | 0.16563973 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GPX3 | GPX3 Entrez, Source | glutathione peroxidase 3 (plasma) | 286 | 0.256 | 0.0269 | No |
| 2 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 459 | 0.193 | 0.0506 | No |
| 3 | LOXL1 | LOXL1 Entrez, Source | lysyl oxidase-like 1 | 1137 | 0.113 | 0.0209 | No |
| 4 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 1183 | 0.110 | 0.0384 | No |
| 5 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 1245 | 0.108 | 0.0542 | No |
| 6 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2059 | 0.071 | 0.0064 | No |
| 7 | HMOX2 | HMOX2 Entrez, Source | heme oxygenase (decycling) 2 | 2775 | 0.053 | -0.0373 | No |
| 8 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 2827 | 0.052 | -0.0313 | No |
| 9 | HSD17B8 | HSD17B8 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 8 | 3145 | 0.045 | -0.0466 | No |
| 10 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 3323 | 0.042 | -0.0519 | No |
| 11 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 3372 | 0.041 | -0.0478 | No |
| 12 | GPX4 | GPX4 Entrez, Source | glutathione peroxidase 4 (phospholipid hydroperoxidase) | 3543 | 0.038 | -0.0534 | No |
| 13 | NOX4 | NOX4 Entrez, Source | NADPH oxidase 4 | 4346 | 0.025 | -0.1091 | No |
| 14 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 4664 | 0.020 | -0.1292 | No |
| 15 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 4980 | 0.015 | -0.1500 | No |
| 16 | QSCN6 | QSCN6 Entrez, Source | quiescin Q6 | 5385 | 0.010 | -0.1785 | No |
| 17 | PAM | PAM Entrez, Source | peptidylglycine alpha-amidating monooxygenase | 5501 | 0.008 | -0.1856 | No |
| 18 | PHGDH | PHGDH Entrez, Source | phosphoglycerate dehydrogenase | 5695 | 0.006 | -0.1991 | No |
| 19 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 5737 | 0.005 | -0.2012 | No |
| 20 | COX15 | COX15 Entrez, Source | COX15 homolog, cytochrome c oxidase assembly protein (yeast) | 5945 | 0.003 | -0.2162 | No |
| 21 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 6558 | -0.005 | -0.2613 | No |
| 22 | TXN2 | TXN2 Entrez, Source | thioredoxin 2 | 6588 | -0.006 | -0.2625 | No |
| 23 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 6671 | -0.007 | -0.2674 | No |
| 24 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 6734 | -0.007 | -0.2706 | No |
| 25 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 6866 | -0.009 | -0.2788 | No |
| 26 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 7060 | -0.011 | -0.2912 | No |
| 27 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 7106 | -0.012 | -0.2923 | No |
| 28 | CYP11A1 | CYP11A1 Entrez, Source | cytochrome P450, family 11, subfamily A, polypeptide 1 | 7492 | -0.017 | -0.3182 | No |
| 29 | MTRR | MTRR Entrez, Source | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 7592 | -0.018 | -0.3222 | No |
| 30 | ETFB | ETFB Entrez, Source | electron-transfer-flavoprotein, beta polypeptide | 8173 | -0.026 | -0.3609 | No |
| 31 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 8238 | -0.027 | -0.3606 | No |
| 32 | PRDX5 | PRDX5 Entrez, Source | peroxiredoxin 5 | 8294 | -0.028 | -0.3595 | No |
| 33 | COX5A | COX5A Entrez, Source | cytochrome c oxidase subunit Va | 8314 | -0.028 | -0.3556 | No |
| 34 | CYP1A2 | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 8681 | -0.033 | -0.3769 | No |
| 35 | SARDH | SARDH Entrez, Source | sarcosine dehydrogenase | 8785 | -0.035 | -0.3781 | No |
| 36 | GPX2 | GPX2 Entrez, Source | glutathione peroxidase 2 (gastrointestinal) | 8829 | -0.035 | -0.3747 | No |
| 37 | SPR | SPR Entrez, Source | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 9360 | -0.043 | -0.4065 | No |
| 38 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 9455 | -0.044 | -0.4052 | No |
| 39 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 9857 | -0.051 | -0.4257 | No |
| 40 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 10320 | -0.059 | -0.4494 | Yes |
| 41 | NCF1 | NCF1 Entrez, Source | neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) | 10343 | -0.059 | -0.4398 | Yes |
| 42 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 10414 | -0.060 | -0.4336 | Yes |
| 43 | MB | MB Entrez, Source | myoglobin | 10581 | -0.064 | -0.4340 | Yes |
| 44 | GSR | GSR Entrez, Source | glutathione reductase | 10698 | -0.066 | -0.4303 | Yes |
| 45 | P4HB | P4HB Entrez, Source | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide | 10713 | -0.066 | -0.4187 | Yes |
| 46 | CYP1B1 | CYP1B1 Entrez, Source | cytochrome P450, family 1, subfamily B, polypeptide 1 | 10964 | -0.073 | -0.4238 | Yes |
| 47 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 11025 | -0.074 | -0.4144 | Yes |
| 48 | TXNL2 | TXNL2 Entrez, Source | thioredoxin-like 2 | 11101 | -0.076 | -0.4057 | Yes |
| 49 | AKR1B10 | AKR1B10 Entrez, Source | aldo-keto reductase family 1, member B10 (aldose reductase) | 11557 | -0.088 | -0.4233 | Yes |
| 50 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 12067 | -0.106 | -0.4416 | Yes |
| 51 | AKR7A2 | AKR7A2 Entrez, Source | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 12358 | -0.119 | -0.4410 | Yes |
| 52 | BLVRA | BLVRA Entrez, Source | biliverdin reductase A | 12414 | -0.122 | -0.4220 | Yes |
| 53 | DHRS4 | DHRS4 Entrez, Source | dehydrogenase/reductase (SDR family) member 4 | 12452 | -0.124 | -0.4014 | Yes |
| 54 | HAAO | HAAO Entrez, Source | 3-hydroxyanthranilate 3,4-dioxygenase | 12465 | -0.125 | -0.3786 | Yes |
| 55 | CDO1 | CDO1 Entrez, Source | cysteine dioxygenase, type I | 12594 | -0.134 | -0.3628 | Yes |
| 56 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 12729 | -0.144 | -0.3456 | Yes |
| 57 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 12820 | -0.155 | -0.3231 | Yes |
| 58 | AKR7A3 | AKR7A3 Entrez, Source | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 12850 | -0.159 | -0.2952 | Yes |
| 59 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 12882 | -0.162 | -0.2668 | Yes |
| 60 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 12915 | -0.167 | -0.2376 | Yes |
| 61 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 12962 | -0.175 | -0.2080 | Yes |
| 62 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 12987 | -0.180 | -0.1756 | Yes |
| 63 | HNRPM | HNRPM Entrez, Source | heterogeneous nuclear ribonucleoprotein M | 13047 | -0.197 | -0.1428 | Yes |
| 64 | NQO2 | NQO2 Entrez, Source | NAD(P)H dehydrogenase, quinone 2 | 13091 | -0.207 | -0.1068 | Yes |
| 65 | CYP26A1 | CYP26A1 Entrez, Source | cytochrome P450, family 26, subfamily A, polypeptide 1 | 13188 | -0.246 | -0.0674 | Yes |
| 66 | KMO | KMO Entrez, Source | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 13304 | -0.417 | 0.0029 | Yes |
