Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ESR_FIBROBLAST_UP |
| Enrichment Score (ES) | 0.73773736 |
| Normalized Enrichment Score (NES) | 2.2078114 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.4363853E-4 |
| FWER p-Value | 0.0020 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VIM | VIM Entrez, Source | vimentin | 6 | 0.953 | 0.1900 | Yes |
| 2 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 10 | 0.815 | 0.3526 | Yes |
| 3 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 15 | 0.737 | 0.4996 | Yes |
| 4 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 32 | 0.660 | 0.6301 | Yes |
| 5 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 118 | 0.402 | 0.7040 | Yes |
| 6 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 567 | 0.170 | 0.7043 | Yes |
| 7 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 785 | 0.141 | 0.7162 | Yes |
| 8 | ARPC1B | ARPC1B Entrez, Source | actin related protein 2/3 complex, subunit 1B, 41kDa | 1071 | 0.116 | 0.7180 | Yes |
| 9 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 1338 | 0.102 | 0.7183 | Yes |
| 10 | ZFP36L1 | ZFP36L1 Entrez, Source | zinc finger protein 36, C3H type-like 1 | 1350 | 0.101 | 0.7377 | Yes |
| 11 | BNIP3L | BNIP3L Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 1863 | 0.078 | 0.7148 | No |
| 12 | FN1 | FN1 Entrez, Source | fibronectin 1 | 2637 | 0.057 | 0.6680 | No |
| 13 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 3372 | 0.041 | 0.6211 | No |
| 14 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 3538 | 0.038 | 0.6162 | No |
| 15 | EFNB1 | EFNB1 Entrez, Source | ephrin-B1 | 3795 | 0.034 | 0.6037 | No |
| 16 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 3967 | 0.031 | 0.5970 | No |
| 17 | TBCA | TBCA Entrez, Source | tubulin-specific chaperone a | 5793 | 0.005 | 0.4608 | No |
| 18 | MARK3 | MARK3 Entrez, Source | MAP/microtubule affinity-regulating kinase 3 | 6493 | -0.004 | 0.4092 | No |
| 19 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 6962 | -0.010 | 0.3760 | No |
| 20 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 7029 | -0.011 | 0.3733 | No |
| 21 | FLOT1 | FLOT1 Entrez, Source | flotillin 1 | 7222 | -0.013 | 0.3615 | No |
| 22 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 7409 | -0.015 | 0.3506 | No |
| 23 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 7435 | -0.016 | 0.3519 | No |
| 24 | ATP5I | ATP5I Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E | 7717 | -0.020 | 0.3347 | No |
| 25 | OAZ1 | OAZ1 Entrez, Source | ornithine decarboxylase antizyme 1 | 7785 | -0.021 | 0.3338 | No |
| 26 | TPR | TPR Entrez, Source | translocated promoter region (to activated MET oncogene) | 7863 | -0.022 | 0.3323 | No |
| 27 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7962 | -0.023 | 0.3295 | No |
| 28 | TXNRD2 | TXNRD2 Entrez, Source | thioredoxin reductase 2 | 8114 | -0.025 | 0.3232 | No |
| 29 | EIF3S6IP | EIF3S6IP Entrez, Source | eukaryotic translation initiation factor 3, subunit 6 interacting protein | 8567 | -0.032 | 0.2956 | No |
| 30 | GOLPH3 | GOLPH3 Entrez, Source | golgi phosphoprotein 3 (coat-protein) | 9107 | -0.039 | 0.2629 | No |
| 31 | HGF | HGF Entrez, Source | hepatocyte growth factor (hepapoietin A; scatter factor) | 10486 | -0.062 | 0.1717 | No |
| 32 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 11781 | -0.095 | 0.0934 | No |
| 33 | FGFR4 | FGFR4 Entrez, Source | fibroblast growth factor receptor 4 | 12369 | -0.119 | 0.0731 | No |
