Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ET743_HELA_UP |
| Enrichment Score (ES) | 0.61093044 |
| Normalized Enrichment Score (NES) | 1.9111567 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0143143935 |
| FWER p-Value | 0.569 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 5 | 0.972 | 0.1320 | Yes |
| 2 | CLDN7 | CLDN7 Entrez, Source | claudin 7 | 7 | 0.940 | 0.2599 | Yes |
| 3 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 10 | 0.815 | 0.3709 | Yes |
| 4 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 42 | 0.616 | 0.4524 | Yes |
| 5 | EML2 | EML2 Entrez, Source | echinoderm microtubule associated protein like 2 | 139 | 0.373 | 0.4959 | Yes |
| 6 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 218 | 0.309 | 0.5322 | Yes |
| 7 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 337 | 0.234 | 0.5552 | Yes |
| 8 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 553 | 0.172 | 0.5625 | Yes |
| 9 | CPE | CPE Entrez, Source | carboxypeptidase E | 589 | 0.167 | 0.5825 | Yes |
| 10 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 722 | 0.148 | 0.5927 | Yes |
| 11 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 744 | 0.145 | 0.6109 | Yes |
| 12 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 1245 | 0.108 | 0.5880 | No |
| 13 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 1285 | 0.105 | 0.5993 | No |
| 14 | NUCB2 | NUCB2 Entrez, Source | nucleobindin 2 | 1503 | 0.094 | 0.5958 | No |
| 15 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 1925 | 0.075 | 0.5744 | No |
| 16 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2059 | 0.071 | 0.5741 | No |
| 17 | ARL6IP1 | ARL6IP1 Entrez, Source | ADP-ribosylation factor-like 6 interacting protein 1 | 2527 | 0.059 | 0.5470 | No |
| 18 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 2597 | 0.058 | 0.5497 | No |
| 19 | CBS | CBS Entrez, Source | cystathionine-beta-synthase | 2663 | 0.056 | 0.5524 | No |
| 20 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 3143 | 0.046 | 0.5226 | No |
| 21 | FOLR1 | FOLR1 Entrez, Source | folate receptor 1 (adult) | 3240 | 0.044 | 0.5214 | No |
| 22 | CLU | CLU Entrez, Source | clusterin | 3299 | 0.043 | 0.5228 | No |
| 23 | GSTA4 | GSTA4 Entrez, Source | glutathione S-transferase A4 | 3997 | 0.030 | 0.4745 | No |
| 24 | AES | AES Entrez, Source | amino-terminal enhancer of split | 4269 | 0.026 | 0.4576 | No |
| 25 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 4953 | 0.016 | 0.4084 | No |
| 26 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 5788 | 0.005 | 0.3464 | No |
| 27 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 6410 | -0.003 | 0.3001 | No |
| 28 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 6766 | -0.008 | 0.2745 | No |
| 29 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 7435 | -0.016 | 0.2264 | No |
| 30 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 7491 | -0.017 | 0.2246 | No |
| 31 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 7976 | -0.023 | 0.1913 | No |
| 32 | PROS1 | PROS1 Entrez, Source | protein S (alpha) | 8724 | -0.034 | 0.1398 | No |
| 33 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 10156 | -0.056 | 0.0398 | No |
| 34 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 10861 | -0.070 | -0.0036 | No |
| 35 | ASNS | ASNS Entrez, Source | asparagine synthetase | 11024 | -0.074 | -0.0057 | No |
| 36 | FGG | FGG Entrez, Source | fibrinogen gamma chain | 11249 | -0.080 | -0.0117 | No |
| 37 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 11841 | -0.097 | -0.0428 | No |
| 38 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 12406 | -0.122 | -0.0687 | No |
| 39 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 12861 | -0.160 | -0.0810 | No |
| 40 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 13070 | -0.202 | -0.0692 | No |
| 41 | CSRP2 | CSRP2 Entrez, Source | cysteine and glycine-rich protein 2 | 13262 | -0.313 | -0.0409 | No |
| 42 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 13279 | -0.344 | 0.0047 | No |
