Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ET743_SARCOMA_UP |
| Enrichment Score (ES) | 0.5583119 |
| Normalized Enrichment Score (NES) | 1.7586143 |
| Nominal p-value | 0.001776199 |
| FDR q-value | 0.03866385 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 10 | 0.815 | 0.1948 | Yes |
| 2 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 218 | 0.309 | 0.2534 | Yes |
| 3 | IFITM2 | IFITM2 Entrez, Source | interferon induced transmembrane protein 2 (1-8D) | 281 | 0.260 | 0.3112 | Yes |
| 4 | AKAP13 | AKAP13 Entrez, Source | A kinase (PRKA) anchor protein 13 | 336 | 0.235 | 0.3634 | Yes |
| 5 | LYZ | LYZ Entrez, Source | lysozyme (renal amyloidosis) | 424 | 0.202 | 0.4053 | Yes |
| 6 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 866 | 0.132 | 0.4039 | Yes |
| 7 | HSBP1 | HSBP1 Entrez, Source | heat shock factor binding protein 1 | 877 | 0.131 | 0.4346 | Yes |
| 8 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 1045 | 0.118 | 0.4503 | Yes |
| 9 | WBP1 | WBP1 Entrez, Source | WW domain binding protein 1 | 1181 | 0.110 | 0.4666 | Yes |
| 10 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 1285 | 0.105 | 0.4840 | Yes |
| 11 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 1444 | 0.096 | 0.4952 | Yes |
| 12 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 1550 | 0.092 | 0.5092 | Yes |
| 13 | GUK1 | GUK1 Entrez, Source | guanylate kinase 1 | 1568 | 0.091 | 0.5297 | Yes |
| 14 | LAPTM4A | LAPTM4A Entrez, Source | lysosomal-associated protein transmembrane 4 alpha | 1569 | 0.091 | 0.5514 | Yes |
| 15 | DKK3 | DKK3 Entrez, Source | dickkopf homolog 3 (Xenopus laevis) | 1742 | 0.083 | 0.5583 | Yes |
| 16 | ITGAE | ITGAE Entrez, Source | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 2093 | 0.070 | 0.5488 | No |
| 17 | SERTAD1 | SERTAD1 Entrez, Source | SERTA domain containing 1 | 3172 | 0.045 | 0.4785 | No |
| 18 | SKP1A | SKP1A Entrez, Source | S-phase kinase-associated protein 1A (p19A) | 3287 | 0.043 | 0.4802 | No |
| 19 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 3372 | 0.041 | 0.4838 | No |
| 20 | GNAS | GNAS Entrez, Source | GNAS complex locus | 3379 | 0.041 | 0.4931 | No |
| 21 | UQCRB | UQCRB Entrez, Source | ubiquinol-cytochrome c reductase binding protein | 3490 | 0.039 | 0.4941 | No |
| 22 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 3739 | 0.035 | 0.4838 | No |
| 23 | COX8A | COX8A Entrez, Source | cytochrome c oxidase subunit 8A (ubiquitous) | 4033 | 0.030 | 0.4689 | No |
| 24 | COX7A2 | COX7A2 Entrez, Source | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 4338 | 0.025 | 0.4520 | No |
| 25 | DNM1L | DNM1L Entrez, Source | dynamin 1-like | 4783 | 0.018 | 0.4230 | No |
| 26 | PDIA3 | PDIA3 Entrez, Source | protein disulfide isomerase family A, member 3 | 4843 | 0.018 | 0.4228 | No |
| 27 | PPGB | PPGB Entrez, Source | protective protein for beta-galactosidase (galactosialidosis) | 5068 | 0.014 | 0.4094 | No |
| 28 | GNG10 | GNG10 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 10 | 5367 | 0.010 | 0.3894 | No |
| 29 | SCG5 | SCG5 Entrez, Source | secretogranin V (7B2 protein) | 5677 | 0.006 | 0.3676 | No |
| 30 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 5737 | 0.005 | 0.3644 | No |
| 31 | CDC37 | CDC37 Entrez, Source | CDC37 cell division cycle 37 homolog (S. cerevisiae) | 5747 | 0.005 | 0.3650 | No |
| 32 | FKBP1A | FKBP1A Entrez, Source | FK506 binding protein 1A, 12kDa | 6282 | -0.002 | 0.3253 | No |
| 33 | IGFBP6 | IGFBP6 Entrez, Source | insulin-like growth factor binding protein 6 | 6428 | -0.004 | 0.3152 | No |
| 34 | ITM2B | ITM2B Entrez, Source | integral membrane protein 2B | 7038 | -0.011 | 0.2721 | No |
| 35 | HDAC3 | HDAC3 Entrez, Source | histone deacetylase 3 | 7165 | -0.013 | 0.2656 | No |
| 36 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7962 | -0.023 | 0.2113 | No |
| 37 | SOCS1 | SOCS1 Entrez, Source | suppressor of cytokine signaling 1 | 8877 | -0.036 | 0.1511 | No |
| 38 | VKORC1 | VKORC1 Entrez, Source | vitamin K epoxide reductase complex, subunit 1 | 8958 | -0.037 | 0.1540 | No |
| 39 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 9144 | -0.039 | 0.1495 | No |
| 40 | NDUFA1 | NDUFA1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | 10602 | -0.064 | 0.0554 | No |
| 41 | ARL2 | ARL2 Entrez, Source | ADP-ribosylation factor-like 2 | 11242 | -0.080 | 0.0264 | No |
| 42 | RPS27 | RPS27 Entrez, Source | ribosomal protein S27 (metallopanstimulin 1) | 11258 | -0.080 | 0.0445 | No |
| 43 | GLO1 | GLO1 Entrez, Source | glyoxalase I | 11333 | -0.082 | 0.0587 | No |
| 44 | UBA52 | UBA52 Entrez, Source | ubiquitin A-52 residue ribosomal protein fusion product 1 | 11752 | -0.094 | 0.0497 | No |
| 45 | IFITM3 | IFITM3 Entrez, Source | interferon induced transmembrane protein 3 (1-8U) | 11860 | -0.098 | 0.0652 | No |
| 46 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 13029 | -0.193 | 0.0235 | No |
