Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | GLYCOLYSIS_AND_GLUCONEOGENESIS |
| Enrichment Score (ES) | 0.59074605 |
| Normalized Enrichment Score (NES) | 1.8196031 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.029476073 |
| FWER p-Value | 0.945 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 52 | 0.576 | 0.1208 | Yes |
| 2 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 59 | 0.557 | 0.2409 | Yes |
| 3 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 60 | 0.555 | 0.3610 | Yes |
| 4 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 61 | 0.555 | 0.4811 | Yes |
| 5 | HK1 | HK1 Entrez, Source | hexokinase 1 | 197 | 0.323 | 0.5410 | Yes |
| 6 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 439 | 0.198 | 0.5658 | Yes |
| 7 | DLAT | DLAT Entrez, Source | dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) | 766 | 0.143 | 0.5723 | Yes |
| 8 | PC | PC Entrez, Source | pyruvate carboxylase | 895 | 0.130 | 0.5907 | Yes |
| 9 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 2140 | 0.069 | 0.5121 | No |
| 10 | PGAM2 | PGAM2 Entrez, Source | phosphoglycerate mutase 2 (muscle) | 2529 | 0.059 | 0.4957 | No |
| 11 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 3325 | 0.042 | 0.4451 | No |
| 12 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 3915 | 0.032 | 0.4076 | No |
| 13 | GAPDHS | GAPDHS Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | 4301 | 0.025 | 0.3842 | No |
| 14 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 4734 | 0.019 | 0.3559 | No |
| 15 | GAPDH | GAPDH Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase | 4797 | 0.018 | 0.3552 | No |
| 16 | PGAM1 | PGAM1 Entrez, Source | phosphoglycerate mutase 1 (brain) | 5246 | 0.012 | 0.3241 | No |
| 17 | FBP2 | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 5353 | 0.010 | 0.3183 | No |
| 18 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 5519 | 0.008 | 0.3077 | No |
| 19 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 5585 | 0.007 | 0.3043 | No |
| 20 | ENO2 | ENO2 Entrez, Source | enolase 2 (gamma, neuronal) | 6221 | -0.001 | 0.2568 | No |
| 21 | PDHA1 | PDHA1 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 1 | 6412 | -0.003 | 0.2433 | No |
| 22 | GPI | GPI Entrez, Source | glucose phosphate isomerase | 6561 | -0.005 | 0.2333 | No |
| 23 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 7433 | -0.016 | 0.1712 | No |
| 24 | HK2 | HK2 Entrez, Source | hexokinase 2 | 7823 | -0.021 | 0.1465 | No |
| 25 | LDHAL6B | LDHAL6B Entrez, Source | lactate dehydrogenase A-like 6B | 8588 | -0.032 | 0.0961 | No |
| 26 | PDHB | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 8709 | -0.034 | 0.0944 | No |
| 27 | MDH2 | MDH2 Entrez, Source | malate dehydrogenase 2, NAD (mitochondrial) | 8772 | -0.034 | 0.0972 | No |
| 28 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 8794 | -0.035 | 0.1031 | No |
| 29 | MDH1 | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 9065 | -0.038 | 0.0912 | No |
| 30 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 9144 | -0.039 | 0.0938 | No |
| 31 | ENO3 | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 9266 | -0.041 | 0.0936 | No |
| 32 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 9509 | -0.045 | 0.0852 | No |
| 33 | LDHC | LDHC Entrez, Source | lactate dehydrogenase C | 10141 | -0.056 | 0.0499 | No |
| 34 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 10295 | -0.058 | 0.0510 | No |
| 35 | PDHA2 | PDHA2 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 2 | 10385 | -0.060 | 0.0573 | No |
| 36 | GCK | GCK Entrez, Source | glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | 13266 | -0.315 | -0.0909 | No |
| 37 | PKLR | PKLR Entrez, Source | pyruvate kinase, liver and RBC | 13313 | -0.446 | 0.0022 | No |
