Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | H2O2_CSBRESCUED_C1_UP |
| Enrichment Score (ES) | 0.61885834 |
| Normalized Enrichment Score (NES) | 1.82146 |
| Nominal p-value | 0.003508772 |
| FDR q-value | 0.029367201 |
| FWER p-Value | 0.938 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GDF15 | GDF15 Entrez, Source | growth differentiation factor 15 | 58 | 0.559 | 0.1451 | Yes |
| 2 | ANKRD1 | ANKRD1 Entrez, Source | ankyrin repeat domain 1 (cardiac muscle) | 63 | 0.532 | 0.2868 | Yes |
| 3 | CRYAB | CRYAB Entrez, Source | crystallin, alpha B | 141 | 0.371 | 0.3802 | Yes |
| 4 | SERPINH1 | SERPINH1 Entrez, Source | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 181 | 0.336 | 0.4670 | Yes |
| 5 | PTGER4 | PTGER4 Entrez, Source | prostaglandin E receptor 4 (subtype EP4) | 361 | 0.225 | 0.5138 | Yes |
| 6 | SLC20A1 | SLC20A1 Entrez, Source | solute carrier family 20 (phosphate transporter), member 1 | 543 | 0.173 | 0.5464 | Yes |
| 7 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 577 | 0.168 | 0.5888 | Yes |
| 8 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 710 | 0.149 | 0.6189 | Yes |
| 9 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 1285 | 0.105 | 0.6038 | No |
| 10 | HCFC1R1 | HCFC1R1 Entrez, Source | host cell factor C1 regulator 1 (XPO1 dependent) | 1668 | 0.086 | 0.5981 | No |
| 11 | PKIA | PKIA Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 2727 | 0.054 | 0.5331 | No |
| 12 | ATP6V1C2 | ATP6V1C2 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | 3316 | 0.042 | 0.5002 | No |
| 13 | ATP6AP1 | ATP6AP1 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 1 | 4367 | 0.024 | 0.4278 | No |
| 14 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 4471 | 0.023 | 0.4261 | No |
| 15 | PSMC4 | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 4709 | 0.019 | 0.4135 | No |
| 16 | PPP1CA | PPP1CA Entrez, Source | protein phosphatase 1, catalytic subunit, alpha isoform | 5040 | 0.015 | 0.3927 | No |
| 17 | COX6C | COX6C Entrez, Source | cytochrome c oxidase subunit VIc | 5343 | 0.010 | 0.3728 | No |
| 18 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 6001 | 0.002 | 0.3240 | No |
| 19 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 6260 | -0.001 | 0.3050 | No |
| 20 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 6950 | -0.010 | 0.2560 | No |
| 21 | ZBTB7A | ZBTB7A Entrez, Source | zinc finger and BTB domain containing 7A | 7801 | -0.021 | 0.1977 | No |
| 22 | ENG | ENG Entrez, Source | endoglin (Osler-Rendu-Weber syndrome 1) | 8089 | -0.025 | 0.1828 | No |
| 23 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 8535 | -0.031 | 0.1577 | No |
| 24 | RPL5 | RPL5 Entrez, Source | ribosomal protein L5 | 9787 | -0.050 | 0.0771 | No |
| 25 | CTSB | CTSB Entrez, Source | cathepsin B | 10352 | -0.059 | 0.0506 | No |
| 26 | CCNH | CCNH Entrez, Source | cyclin H | 10973 | -0.073 | 0.0234 | No |
| 27 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 11707 | -0.092 | -0.0070 | No |
| 28 | HMOX1 | HMOX1 Entrez, Source | heme oxygenase (decycling) 1 | 12319 | -0.117 | -0.0217 | No |
| 29 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 12861 | -0.160 | -0.0195 | No |
| 30 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13096 | -0.208 | 0.0185 | No |
