Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | H2O2_CSBRESCUED_UP |
| Enrichment Score (ES) | 0.61957806 |
| Normalized Enrichment Score (NES) | 1.8467538 |
| Nominal p-value | 0.0018348624 |
| FDR q-value | 0.023931855 |
| FWER p-Value | 0.865 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GDF15 | GDF15 Entrez, Source | growth differentiation factor 15 | 58 | 0.559 | 0.1240 | Yes |
| 2 | ANKRD1 | ANKRD1 Entrez, Source | ankyrin repeat domain 1 (cardiac muscle) | 63 | 0.532 | 0.2458 | Yes |
| 3 | CRYAB | CRYAB Entrez, Source | crystallin, alpha B | 141 | 0.371 | 0.3253 | Yes |
| 4 | SERPINH1 | SERPINH1 Entrez, Source | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 181 | 0.336 | 0.3995 | Yes |
| 5 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 337 | 0.234 | 0.4415 | Yes |
| 6 | PTGER4 | PTGER4 Entrez, Source | prostaglandin E receptor 4 (subtype EP4) | 361 | 0.225 | 0.4916 | Yes |
| 7 | CUTL1 | CUTL1 Entrez, Source | cut-like 1, CCAAT displacement protein (Drosophila) | 516 | 0.180 | 0.5213 | Yes |
| 8 | SLC20A1 | SLC20A1 Entrez, Source | solute carrier family 20 (phosphate transporter), member 1 | 543 | 0.173 | 0.5591 | Yes |
| 9 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 577 | 0.168 | 0.5952 | Yes |
| 10 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 710 | 0.149 | 0.6196 | Yes |
| 11 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 1285 | 0.105 | 0.6005 | No |
| 12 | HCFC1R1 | HCFC1R1 Entrez, Source | host cell factor C1 regulator 1 (XPO1 dependent) | 1668 | 0.086 | 0.5916 | No |
| 13 | CST3 | CST3 Entrez, Source | cystatin C (amyloid angiopathy and cerebral hemorrhage) | 1692 | 0.085 | 0.6094 | No |
| 14 | PKIA | PKIA Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 2727 | 0.054 | 0.5441 | No |
| 15 | ATP6V1C2 | ATP6V1C2 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | 3316 | 0.042 | 0.5096 | No |
| 16 | ATP6AP1 | ATP6AP1 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 1 | 4367 | 0.024 | 0.4363 | No |
| 17 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 4471 | 0.023 | 0.4337 | No |
| 18 | PSMC4 | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 4709 | 0.019 | 0.4204 | No |
| 19 | PPP1CA | PPP1CA Entrez, Source | protein phosphatase 1, catalytic subunit, alpha isoform | 5040 | 0.015 | 0.3990 | No |
| 20 | COX6C | COX6C Entrez, Source | cytochrome c oxidase subunit VIc | 5343 | 0.010 | 0.3787 | No |
| 21 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 5788 | 0.005 | 0.3464 | No |
| 22 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 6001 | 0.002 | 0.3309 | No |
| 23 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 6260 | -0.001 | 0.3119 | No |
| 24 | BAG4 | BAG4 Entrez, Source | BCL2-associated athanogene 4 | 6325 | -0.002 | 0.3076 | No |
| 25 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 6950 | -0.010 | 0.2630 | No |
| 26 | DNAJA1 | DNAJA1 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 1 | 7683 | -0.019 | 0.2124 | No |
| 27 | ZBTB7A | ZBTB7A Entrez, Source | zinc finger and BTB domain containing 7A | 7801 | -0.021 | 0.2084 | No |
| 28 | ENG | ENG Entrez, Source | endoglin (Osler-Rendu-Weber syndrome 1) | 8089 | -0.025 | 0.1925 | No |
| 29 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 8524 | -0.031 | 0.1670 | No |
| 30 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 8535 | -0.031 | 0.1734 | No |
| 31 | RPL5 | RPL5 Entrez, Source | ribosomal protein L5 | 9787 | -0.050 | 0.0909 | No |
| 32 | RPL31 | RPL31 Entrez, Source | ribosomal protein L31 | 10162 | -0.056 | 0.0757 | No |
| 33 | CTSB | CTSB Entrez, Source | cathepsin B | 10352 | -0.059 | 0.0751 | No |
| 34 | CCNH | CCNH Entrez, Source | cyclin H | 10973 | -0.073 | 0.0452 | No |
| 35 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 11707 | -0.092 | 0.0113 | No |
| 36 | HMOX1 | HMOX1 Entrez, Source | heme oxygenase (decycling) 1 | 12319 | -0.117 | -0.0078 | No |
| 37 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 12861 | -0.160 | -0.0117 | No |
| 38 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13096 | -0.208 | 0.0185 | No |
