Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HADDAD_HSC_CD7_DN |
| Enrichment Score (ES) | 0.5401443 |
| Normalized Enrichment Score (NES) | 1.7472587 |
| Nominal p-value | 0.0016977929 |
| FDR q-value | 0.04164347 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ARMCX2 | ARMCX2 Entrez, Source | armadillo repeat containing, X-linked 2 | 19 | 0.707 | 0.1416 | Yes |
| 2 | LOX | LOX Entrez, Source | lysyl oxidase | 82 | 0.465 | 0.2311 | Yes |
| 3 | FOXO1A | FOXO1A Entrez, Source | forkhead box O1A (rhabdomyosarcoma) | 213 | 0.311 | 0.2842 | Yes |
| 4 | GRK5 | GRK5 Entrez, Source | G protein-coupled receptor kinase 5 | 401 | 0.209 | 0.3125 | Yes |
| 5 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 406 | 0.208 | 0.3543 | Yes |
| 6 | F2RL1 | F2RL1 Entrez, Source | coagulation factor II (thrombin) receptor-like 1 | 508 | 0.181 | 0.3833 | Yes |
| 7 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 744 | 0.145 | 0.3950 | Yes |
| 8 | MLLT3 | MLLT3 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 808 | 0.139 | 0.4183 | Yes |
| 9 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 1084 | 0.116 | 0.4210 | Yes |
| 10 | PTPRD | PTPRD Entrez, Source | protein tyrosine phosphatase, receptor type, D | 1088 | 0.116 | 0.4442 | Yes |
| 11 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 1183 | 0.110 | 0.4594 | Yes |
| 12 | ARG2 | ARG2 Entrez, Source | arginase, type II | 1251 | 0.107 | 0.4761 | Yes |
| 13 | PRG2 | PRG2 Entrez, Source | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 1362 | 0.100 | 0.4882 | Yes |
| 14 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 1404 | 0.098 | 0.5049 | Yes |
| 15 | HMGA2 | HMGA2 Entrez, Source | high mobility group AT-hook 2 | 1465 | 0.096 | 0.5197 | Yes |
| 16 | BCLAF1 | BCLAF1 Entrez, Source | BCL2-associated transcription factor 1 | 1588 | 0.090 | 0.5287 | Yes |
| 17 | KLF9 | KLF9 Entrez, Source | Kruppel-like factor 9 | 1781 | 0.081 | 0.5307 | Yes |
| 18 | GP1BB /// SEPT5 | 1865 | 0.078 | 0.5401 | Yes | ||
| 19 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 2181 | 0.068 | 0.5302 | No |
| 20 | PLCB4 | PLCB4 Entrez, Source | phospholipase C, beta 4 | 2437 | 0.061 | 0.5234 | No |
| 21 | BEX1 | BEX1 Entrez, Source | brain expressed, X-linked 1 | 3322 | 0.042 | 0.4653 | No |
| 22 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 3405 | 0.040 | 0.4673 | No |
| 23 | SERPINI1 | SERPINI1 Entrez, Source | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 5393 | 0.010 | 0.3198 | No |
| 24 | INPP4B | INPP4B Entrez, Source | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5469 | 0.009 | 0.3159 | No |
| 25 | BAG3 | BAG3 Entrez, Source | BCL2-associated athanogene 3 | 5477 | 0.009 | 0.3171 | No |
| 26 | PDZD2 | PDZD2 Entrez, Source | PDZ domain containing 2 | 5562 | 0.007 | 0.3123 | No |
| 27 | CACNB2 | CACNB2 Entrez, Source | calcium channel, voltage-dependent, beta 2 subunit | 5571 | 0.007 | 0.3132 | No |
| 28 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 5926 | 0.003 | 0.2872 | No |
| 29 | FAM3C | FAM3C Entrez, Source | family with sequence similarity 3, member C | 6544 | -0.005 | 0.2417 | No |
| 30 | HSPA5 | HSPA5 Entrez, Source | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 6557 | -0.005 | 0.2419 | No |
| 31 | HTR1F | HTR1F Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 1F | 6727 | -0.007 | 0.2307 | No |
| 32 | SMARCA2 | SMARCA2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 6971 | -0.010 | 0.2145 | No |
| 33 | TJP2 | TJP2 Entrez, Source | tight junction protein 2 (zona occludens 2) | 7094 | -0.012 | 0.2077 | No |
| 34 | CRHBP | CRHBP Entrez, Source | corticotropin releasing hormone binding protein | 7209 | -0.013 | 0.2018 | No |
| 35 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 7809 | -0.021 | 0.1609 | No |
| 36 | PPM1H | PPM1H Entrez, Source | protein phosphatase 1H (PP2C domain containing) | 7856 | -0.021 | 0.1618 | No |
| 37 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 7943 | -0.023 | 0.1599 | No |
| 38 | STCH | STCH Entrez, Source | stress 70 protein chaperone, microsome-associated, 60kDa | 8120 | -0.025 | 0.1518 | No |
| 39 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 8235 | -0.027 | 0.1486 | No |
| 40 | CFH | CFH Entrez, Source | complement factor H | 8669 | -0.033 | 0.1228 | No |
| 41 | DLK1 | DLK1 Entrez, Source | delta-like 1 homolog (Drosophila) | 8739 | -0.034 | 0.1245 | No |
| 42 | LAPTM4B | LAPTM4B Entrez, Source | lysosomal associated protein transmembrane 4 beta | 8874 | -0.036 | 0.1216 | No |
| 43 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 9416 | -0.044 | 0.0897 | No |
| 44 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 9444 | -0.044 | 0.0966 | No |
| 45 | PDE4B | PDE4B Entrez, Source | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) | 9537 | -0.046 | 0.0990 | No |
| 46 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 9586 | -0.047 | 0.1048 | No |
| 47 | HLF | HLF Entrez, Source | hepatic leukemia factor | 9889 | -0.052 | 0.0925 | No |
| 48 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10688 | -0.066 | 0.0458 | No |
| 49 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 10954 | -0.072 | 0.0405 | No |
| 50 | CHN2 | CHN2 Entrez, Source | chimerin (chimaerin) 2 | 11079 | -0.075 | 0.0464 | No |
| 51 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 11674 | -0.091 | 0.0201 | No |
| 52 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12652 | -0.138 | -0.0256 | No |
| 53 | PHLPP | PHLPP Entrez, Source | PH domain and leucine rich repeat protein phosphatase | 12870 | -0.161 | -0.0092 | No |
| 54 | MPDZ | MPDZ Entrez, Source | multiple PDZ domain protein | 13135 | -0.221 | 0.0156 | No |
