Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HDACI_COLON_BUT24HRS_UP |
| Enrichment Score (ES) | 0.5909302 |
| Normalized Enrichment Score (NES) | 1.8085012 |
| Nominal p-value | 0.003649635 |
| FDR q-value | 0.031062672 |
| FWER p-Value | 0.962 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 12 | 0.803 | 0.1865 | Yes |
| 2 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 142 | 0.371 | 0.2632 | Yes |
| 3 | GABBR1 | GABBR1 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 1 | 432 | 0.200 | 0.2883 | Yes |
| 4 | NEU1 | NEU1 Entrez, Source | sialidase 1 (lysosomal sialidase) | 510 | 0.181 | 0.3247 | Yes |
| 5 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 567 | 0.170 | 0.3602 | Yes |
| 6 | IL17RE | IL17RE Entrez, Source | interleukin 17 receptor E | 574 | 0.168 | 0.3990 | Yes |
| 7 | ZSWIM6 | ZSWIM6 Entrez, Source | zinc finger, SWIM-type containing 6 | 600 | 0.165 | 0.4356 | Yes |
| 8 | BIRC4 | BIRC4 Entrez, Source | baculoviral IAP repeat-containing 4 | 630 | 0.161 | 0.4709 | Yes |
| 9 | PLAG1 | PLAG1 Entrez, Source | pleiomorphic adenoma gene 1 | 756 | 0.144 | 0.4951 | Yes |
| 10 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 785 | 0.141 | 0.5259 | Yes |
| 11 | PLCG2 | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 1116 | 0.114 | 0.5276 | Yes |
| 12 | SLC27A1 | SLC27A1 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 1 | 1225 | 0.108 | 0.5448 | Yes |
| 13 | PLD3 | PLD3 Entrez, Source | phospholipase D family, member 3 | 1454 | 0.096 | 0.5500 | Yes |
| 14 | ROCK1 | ROCK1 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 1 | 1513 | 0.093 | 0.5675 | Yes |
| 15 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 1550 | 0.092 | 0.5861 | Yes |
| 16 | CALCOCO1 | CALCOCO1 Entrez, Source | calcium binding and coiled-coil domain 1 | 1744 | 0.083 | 0.5909 | Yes |
| 17 | SPARCL1 | SPARCL1 Entrez, Source | SPARC-like 1 (mast9, hevin) | 1992 | 0.073 | 0.5894 | No |
| 18 | INPP5E | INPP5E Entrez, Source | inositol polyphosphate-5-phosphatase, 72 kDa | 2239 | 0.066 | 0.5864 | No |
| 19 | PSAP | PSAP Entrez, Source | prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) | 3033 | 0.048 | 0.5379 | No |
| 20 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 3256 | 0.044 | 0.5314 | No |
| 21 | CLU | CLU Entrez, Source | clusterin | 3299 | 0.043 | 0.5381 | No |
| 22 | MAP1LC3B | MAP1LC3B Entrez, Source | microtubule-associated protein 1 light chain 3 beta | 3406 | 0.040 | 0.5396 | No |
| 23 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 3681 | 0.036 | 0.5273 | No |
| 24 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 3736 | 0.035 | 0.5313 | No |
| 25 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 3739 | 0.035 | 0.5392 | No |
| 26 | GRN | GRN Entrez, Source | granulin | 3902 | 0.032 | 0.5345 | No |
| 27 | HSP90AA1 | HSP90AA1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 4655 | 0.020 | 0.4826 | No |
| 28 | DNM3 | DNM3 Entrez, Source | dynamin 3 | 4784 | 0.018 | 0.4773 | No |
| 29 | ATP6AP2 | ATP6AP2 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 2 | 6241 | -0.001 | 0.3682 | No |
| 30 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 6565 | -0.005 | 0.3451 | No |
| 31 | CD81 | CD81 Entrez, Source | CD81 molecule | 6698 | -0.007 | 0.3368 | No |
| 32 | PRDX1 | PRDX1 Entrez, Source | peroxiredoxin 1 | 6870 | -0.009 | 0.3261 | No |
| 33 | HSF1 | HSF1 Entrez, Source | heat shock transcription factor 1 | 7875 | -0.022 | 0.2557 | No |
| 34 | FLNB | FLNB Entrez, Source | filamin B, beta (actin binding protein 278) | 8603 | -0.032 | 0.2085 | No |
| 35 | PPM2C | PPM2C Entrez, Source | protein phosphatase 2C, magnesium-dependent, catalytic subunit | 8778 | -0.035 | 0.2035 | No |
| 36 | TSNAX | TSNAX Entrez, Source | translin-associated factor X | 8938 | -0.037 | 0.2002 | No |
| 37 | SMARCD3 | SMARCD3 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | 9321 | -0.042 | 0.1812 | No |
| 38 | CYP1B1 | CYP1B1 Entrez, Source | cytochrome P450, family 1, subfamily B, polypeptide 1 | 10964 | -0.073 | 0.0747 | No |
| 39 | SIPA1 | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 12263 | -0.115 | 0.0039 | No |
| 40 | SKAP2 | SKAP2 Entrez, Source | src kinase associated phosphoprotein 2 | 12646 | -0.138 | 0.0073 | No |
| 41 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 13029 | -0.193 | 0.0235 | No |
