Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HIF1_TARGETS |
| Enrichment Score (ES) | 0.60527223 |
| Normalized Enrichment Score (NES) | 1.7848637 |
| Nominal p-value | 0.0035460992 |
| FDR q-value | 0.03378839 |
| FWER p-Value | 0.984 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 12 | 0.803 | 0.1608 | Yes |
| 2 | ADM | ADM Entrez, Source | adrenomedullin | 34 | 0.649 | 0.2898 | Yes |
| 3 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 113 | 0.410 | 0.3665 | Yes |
| 4 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 145 | 0.367 | 0.4381 | Yes |
| 5 | HK1 | HK1 Entrez, Source | hexokinase 1 | 197 | 0.323 | 0.4993 | Yes |
| 6 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 480 | 0.186 | 0.5156 | Yes |
| 7 | IGFBP1 | IGFBP1 Entrez, Source | insulin-like growth factor binding protein 1 | 531 | 0.177 | 0.5474 | Yes |
| 8 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 567 | 0.170 | 0.5791 | Yes |
| 9 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 699 | 0.150 | 0.5995 | Yes |
| 10 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 1177 | 0.111 | 0.5859 | Yes |
| 11 | SLC2A1 | SLC2A1 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 1 | 1212 | 0.109 | 0.6053 | Yes |
| 12 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 2140 | 0.069 | 0.5495 | No |
| 13 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 3325 | 0.042 | 0.4690 | No |
| 14 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 3915 | 0.032 | 0.4311 | No |
| 15 | GAPDH | GAPDH Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase | 4797 | 0.018 | 0.3686 | No |
| 16 | AK3 | AK3 Entrez, Source | adenylate kinase 3 | 4820 | 0.018 | 0.3705 | No |
| 17 | EPO | EPO Entrez, Source | erythropoietin | 5541 | 0.008 | 0.3180 | No |
| 18 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 5585 | 0.007 | 0.3162 | No |
| 19 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 6700 | -0.007 | 0.2340 | No |
| 20 | HK2 | HK2 Entrez, Source | hexokinase 2 | 7823 | -0.021 | 0.1539 | No |
| 21 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 7976 | -0.023 | 0.1471 | No |
| 22 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 8794 | -0.035 | 0.0928 | No |
| 23 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 9144 | -0.039 | 0.0745 | No |
| 24 | SLC2A3 | SLC2A3 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 3 | 9985 | -0.053 | 0.0221 | No |
| 25 | CP | CP Entrez, Source | ceruloplasmin (ferroxidase) | 10079 | -0.055 | 0.0262 | No |
| 26 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 10686 | -0.066 | -0.0061 | No |
| 27 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 10957 | -0.072 | -0.0118 | No |
| 28 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 11121 | -0.076 | -0.0087 | No |
| 29 | HMOX1 | HMOX1 Entrez, Source | heme oxygenase (decycling) 1 | 12319 | -0.117 | -0.0751 | No |
| 30 | ADRA1B | ADRA1B Entrez, Source | adrenergic, alpha-1B-, receptor | 13257 | -0.310 | -0.0830 | No |
| 31 | TF | TF Entrez, Source | transferrin | 13312 | -0.444 | 0.0023 | No |
