Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HOFMANN_MDS_CD34_LOW_RISK |
| Enrichment Score (ES) | 0.62221974 |
| Normalized Enrichment Score (NES) | 1.7736992 |
| Nominal p-value | 0.0036101083 |
| FDR q-value | 0.03616673 |
| FWER p-Value | 0.994 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GPRC5A | GPRC5A Entrez, Source | G protein-coupled receptor, family C, group 5, member A | 49 | 0.587 | 0.1820 | Yes |
| 2 | GDF15 | GDF15 Entrez, Source | growth differentiation factor 15 | 58 | 0.559 | 0.3582 | Yes |
| 3 | HSPA4 | HSPA4 Entrez, Source | heat shock 70kDa protein 4 | 192 | 0.328 | 0.4518 | Yes |
| 4 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 218 | 0.309 | 0.5477 | Yes |
| 5 | IER3 | IER3 Entrez, Source | immediate early response 3 | 598 | 0.165 | 0.5714 | Yes |
| 6 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 610 | 0.163 | 0.6222 | Yes |
| 7 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 1825 | 0.079 | 0.5561 | No |
| 8 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 2441 | 0.061 | 0.5292 | No |
| 9 | DNM2 | DNM2 Entrez, Source | dynamin 2 | 2662 | 0.056 | 0.5304 | No |
| 10 | TUBB2B | TUBB2B Entrez, Source | tubulin, beta 2B | 2837 | 0.052 | 0.5337 | No |
| 11 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 3006 | 0.048 | 0.5363 | No |
| 12 | CAPNS1 | CAPNS1 Entrez, Source | calpain, small subunit 1 | 4237 | 0.026 | 0.4523 | No |
| 13 | MSX1 | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 4536 | 0.022 | 0.4368 | No |
| 14 | NCLN | NCLN Entrez, Source | nicalin homolog (zebrafish) | 6359 | -0.003 | 0.3008 | No |
| 15 | MALL | MALL Entrez, Source | mal, T-cell differentiation protein-like | 6400 | -0.003 | 0.2988 | No |
| 16 | TOB2 | TOB2 Entrez, Source | transducer of ERBB2, 2 | 7124 | -0.012 | 0.2483 | No |
| 17 | ZMYM3 | ZMYM3 Entrez, Source | zinc finger, MYM-type 3 | 7561 | -0.018 | 0.2211 | No |
| 18 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 7568 | -0.018 | 0.2262 | No |
| 19 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 7976 | -0.023 | 0.2030 | No |
| 20 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 8524 | -0.031 | 0.1717 | No |
| 21 | TSPAN1 | TSPAN1 Entrez, Source | tetraspanin 1 | 8574 | -0.032 | 0.1781 | No |
| 22 | DLK1 | DLK1 Entrez, Source | delta-like 1 homolog (Drosophila) | 8739 | -0.034 | 0.1766 | No |
| 23 | PTPN7 | PTPN7 Entrez, Source | protein tyrosine phosphatase, non-receptor type 7 | 10142 | -0.056 | 0.0889 | No |
| 24 | STIP1 | STIP1 Entrez, Source | stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein) | 10313 | -0.059 | 0.0947 | No |
| 25 | COIL | COIL Entrez, Source | coilin | 10471 | -0.062 | 0.1024 | No |
| 26 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 10870 | -0.070 | 0.0947 | No |
| 27 | PRKCB1 | PRKCB1 Entrez, Source | protein kinase C, beta 1 | 10982 | -0.073 | 0.1094 | No |
| 28 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 11134 | -0.077 | 0.1222 | No |
| 29 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12652 | -0.138 | 0.0518 | No |
