Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HOHENKIRK_MONOCYTE_DEND_DN |
| Enrichment Score (ES) | 0.5425084 |
| Normalized Enrichment Score (NES) | 1.9037294 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.015023651 |
| FWER p-Value | 0.601 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CORO1A | CORO1A Entrez, Source | coronin, actin binding protein, 1A | 41 | 0.620 | 0.0628 | Yes |
| 2 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 44 | 0.606 | 0.1271 | Yes |
| 3 | IL1R2 | IL1R2 Entrez, Source | interleukin 1 receptor, type II | 46 | 0.599 | 0.1907 | Yes |
| 4 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 118 | 0.402 | 0.2281 | Yes |
| 5 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 122 | 0.399 | 0.2703 | Yes |
| 6 | LGALS2 | LGALS2 Entrez, Source | lectin, galactoside-binding, soluble, 2 (galectin 2) | 176 | 0.340 | 0.3025 | Yes |
| 7 | AMPD3 | AMPD3 Entrez, Source | adenosine monophosphate deaminase (isoform E) | 180 | 0.337 | 0.3380 | Yes |
| 8 | PTK2B | PTK2B Entrez, Source | PTK2B protein tyrosine kinase 2 beta | 279 | 0.262 | 0.3585 | Yes |
| 9 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 326 | 0.238 | 0.3803 | Yes |
| 10 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 358 | 0.227 | 0.4021 | Yes |
| 11 | BCAT1 | BCAT1 Entrez, Source | branched chain aminotransferase 1, cytosolic | 396 | 0.210 | 0.4216 | Yes |
| 12 | LYZ | LYZ Entrez, Source | lysozyme (renal amyloidosis) | 424 | 0.202 | 0.4411 | Yes |
| 13 | S100A4 | S100A4 Entrez, Source | S100 calcium binding protein A4 | 450 | 0.195 | 0.4600 | Yes |
| 14 | IER3 | IER3 Entrez, Source | immediate early response 3 | 598 | 0.165 | 0.4664 | Yes |
| 15 | TAX1BP3 | TAX1BP3 Entrez, Source | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 791 | 0.140 | 0.4669 | Yes |
| 16 | PF4 | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 798 | 0.140 | 0.4813 | Yes |
| 17 | HADH2 | HADH2 Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase, type II | 876 | 0.131 | 0.4895 | Yes |
| 18 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 888 | 0.130 | 0.5025 | Yes |
| 19 | IL2RG | IL2RG Entrez, Source | interleukin 2 receptor, gamma (severe combined immunodeficiency) | 927 | 0.127 | 0.5131 | Yes |
| 20 | IL1B | IL1B Entrez, Source | interleukin 1, beta | 1014 | 0.121 | 0.5194 | Yes |
| 21 | PLSCR1 | PLSCR1 Entrez, Source | phospholipid scramblase 1 | 1073 | 0.116 | 0.5274 | Yes |
| 22 | ZFP36L2 | ZFP36L2 Entrez, Source | zinc finger protein 36, C3H type-like 2 | 1206 | 0.109 | 0.5291 | Yes |
| 23 | ITPR1 | ITPR1 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 1 | 1235 | 0.108 | 0.5384 | Yes |
| 24 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 1327 | 0.103 | 0.5425 | Yes |
| 25 | ITGAL | ITGAL Entrez, Source | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 1462 | 0.096 | 0.5425 | Yes |
| 26 | ATP2A3 | ATP2A3 Entrez, Source | ATPase, Ca++ transporting, ubiquitous | 1800 | 0.080 | 0.5256 | No |
| 27 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 1832 | 0.079 | 0.5317 | No |
| 28 | SOS2 | SOS2 Entrez, Source | son of sevenless homolog 2 (Drosophila) | 2013 | 0.073 | 0.5258 | No |
| 29 | LGMN | LGMN Entrez, Source | legumain | 2054 | 0.071 | 0.5304 | No |
| 30 | CD14 | CD14 Entrez, Source | CD14 molecule | 2182 | 0.068 | 0.5280 | No |
| 31 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 2770 | 0.053 | 0.4894 | No |
| 32 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 3143 | 0.046 | 0.4662 | No |
| 33 | RTN1 | RTN1 Entrez, Source | reticulon 1 | 3317 | 0.042 | 0.4576 | No |
| 34 | DNAJC8 | DNAJC8 Entrez, Source | DnaJ (Hsp40) homolog, subfamily C, member 8 | 3556 | 0.038 | 0.4436 | No |
| 35 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 3618 | 0.037 | 0.4429 | No |
| 36 | LTA4H | LTA4H Entrez, Source | leukotriene A4 hydrolase | 3767 | 0.034 | 0.4354 | No |
| 37 | HTRA1 | HTRA1 Entrez, Source | HtrA serine peptidase 1 | 3790 | 0.034 | 0.4373 | No |
| 38 | CTBP1 | CTBP1 Entrez, Source | C-terminal binding protein 1 | 3848 | 0.033 | 0.4365 | No |
| 39 | TXNIP | TXNIP Entrez, Source | thioredoxin interacting protein | 3975 | 0.031 | 0.4302 | No |
| 40 | S100A8 | S100A8 Entrez, Source | S100 calcium binding protein A8 | 4260 | 0.026 | 0.4116 | No |
| 41 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 4288 | 0.026 | 0.4122 | No |
| 42 | ADAM10 | ADAM10 Entrez, Source | ADAM metallopeptidase domain 10 | 4533 | 0.022 | 0.3962 | No |
| 43 | SLC1A3 | SLC1A3 Entrez, Source | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 5237 | 0.012 | 0.3444 | No |
| 44 | CYBB | CYBB Entrez, Source | cytochrome b-245, beta polypeptide (chronic granulomatous disease) | 5548 | 0.008 | 0.3218 | No |
| 45 | PPBP | PPBP Entrez, Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 5643 | 0.006 | 0.3154 | No |
| 46 | PPIB | PPIB Entrez, Source | peptidylprolyl isomerase B (cyclophilin B) | 5713 | 0.006 | 0.3108 | No |
| 47 | BST1 | BST1 Entrez, Source | bone marrow stromal cell antigen 1 | 5735 | 0.005 | 0.3098 | No |
| 48 | BRD2 | BRD2 Entrez, Source | bromodomain containing 2 | 5876 | 0.004 | 0.2996 | No |
| 49 | PPIF | PPIF Entrez, Source | peptidylprolyl isomerase F (cyclophilin F) | 5913 | 0.003 | 0.2972 | No |
| 50 | NAP1L4 | NAP1L4 Entrez, Source | nucleosome assembly protein 1-like 4 | 5935 | 0.003 | 0.2959 | No |
| 51 | NFYC | NFYC Entrez, Source | nuclear transcription factor Y, gamma | 6397 | -0.003 | 0.2615 | No |
| 52 | LST1 | LST1 Entrez, Source | leukocyte specific transcript 1 | 6454 | -0.004 | 0.2577 | No |
| 53 | SERPINA1 | SERPINA1 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 6827 | -0.008 | 0.2305 | No |
| 54 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 7060 | -0.011 | 0.2142 | No |
| 55 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 7289 | -0.014 | 0.1985 | No |
| 56 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 7433 | -0.016 | 0.1894 | No |
| 57 | DOK1 | DOK1 Entrez, Source | docking protein 1, 62kDa (downstream of tyrosine kinase 1) | 7469 | -0.016 | 0.1885 | No |
| 58 | FGL2 | FGL2 Entrez, Source | fibrinogen-like 2 | 7684 | -0.019 | 0.1744 | No |
| 59 | SIAHBP1 | SIAHBP1 Entrez, Source | - | 8490 | -0.031 | 0.1170 | No |
| 60 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 8599 | -0.032 | 0.1122 | No |
| 61 | C3 | C3 Entrez, Source | complement component 3 | 8749 | -0.034 | 0.1046 | No |
| 62 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 8926 | -0.036 | 0.0952 | No |
| 63 | CCR2 | CCR2 Entrez, Source | chemokine (C-C motif) receptor 2 | 8978 | -0.037 | 0.0953 | No |
| 64 | ANPEP | ANPEP Entrez, Source | alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) | 8993 | -0.037 | 0.0982 | No |
| 65 | DHX8 | DHX8 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 9187 | -0.040 | 0.0880 | No |
| 66 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 9367 | -0.043 | 0.0790 | No |
| 67 | IRF7 | IRF7 Entrez, Source | interferon regulatory factor 7 | 9469 | -0.045 | 0.0761 | No |
| 68 | C5AR1 | C5AR1 Entrez, Source | complement component 5a receptor 1 | 9594 | -0.047 | 0.0717 | No |
| 69 | CHI3L1 | CHI3L1 Entrez, Source | chitinase 3-like 1 (cartilage glycoprotein-39) | 9869 | -0.051 | 0.0565 | No |
| 70 | TSC22D1 | TSC22D1 Entrez, Source | TSC22 domain family, member 1 | 9967 | -0.053 | 0.0548 | No |
| 71 | CD37 | CD37 Entrez, Source | CD37 molecule | 10171 | -0.056 | 0.0455 | No |
| 72 | PBEF1 | PBEF1 Entrez, Source | pre-B-cell colony enhancing factor 1 | 10279 | -0.058 | 0.0436 | No |
| 73 | NCF1 | NCF1 Entrez, Source | neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) | 10343 | -0.059 | 0.0452 | No |
| 74 | GSR | GSR Entrez, Source | glutathione reductase | 10698 | -0.066 | 0.0255 | No |
| 75 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 10706 | -0.066 | 0.0320 | No |
| 76 | RASA3 | RASA3 Entrez, Source | RAS p21 protein activator 3 | 11084 | -0.075 | 0.0116 | No |
| 77 | PPP2R5D | PPP2R5D Entrez, Source | protein phosphatase 2, regulatory subunit B (B56), delta isoform | 11192 | -0.078 | 0.0118 | No |
| 78 | CSF1R | CSF1R Entrez, Source | colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog | 11365 | -0.083 | 0.0076 | No |
| 79 | PDLIM7 | PDLIM7 Entrez, Source | PDZ and LIM domain 7 (enigma) | 11377 | -0.083 | 0.0157 | No |
| 80 | SDC2 | SDC2 Entrez, Source | syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) | 11419 | -0.084 | 0.0216 | No |
| 81 | SPINK1 | SPINK1 Entrez, Source | serine peptidase inhibitor, Kazal type 1 | 12063 | -0.106 | -0.0157 | No |
| 82 | BAT2 | BAT2 Entrez, Source | HLA-B associated transcript 2 | 12105 | -0.107 | -0.0074 | No |
| 83 | ALG3 | ALG3 Entrez, Source | asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase) | 12125 | -0.108 | 0.0027 | No |
| 84 | NINJ1 | NINJ1 Entrez, Source | ninjurin 1 | 12581 | -0.133 | -0.0174 | No |
| 85 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 12642 | -0.137 | -0.0074 | No |
| 86 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 12736 | -0.145 | 0.0010 | No |
| 87 | CES1 | CES1 Entrez, Source | carboxylesterase 1 (monocyte/macrophage serine esterase 1) | 13305 | -0.420 | 0.0028 | No |
