Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | HSA00260_GLYCINE_SERINE_AND_THREONINE_METABOLISM |
| Enrichment Score (ES) | -0.4085121 |
| Normalized Enrichment Score (NES) | -1.2642486 |
| Nominal p-value | 0.14651163 |
| FDR q-value | 0.61174285 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GNMT | GNMT Entrez, Source | glycine N-methyltransferase | 236 | 0.293 | 0.0786 | No |
| 2 | SDS | SDS Entrez, Source | serine dehydratase | 507 | 0.181 | 0.1179 | No |
| 3 | CHDH | CHDH Entrez, Source | choline dehydrogenase | 760 | 0.144 | 0.1463 | No |
| 4 | DMGDH | DMGDH Entrez, Source | dimethylglycine dehydrogenase | 1276 | 0.105 | 0.1422 | No |
| 5 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 2100 | 0.070 | 0.1033 | No |
| 6 | CBS | CBS Entrez, Source | cystathionine-beta-synthase | 2663 | 0.056 | 0.0795 | No |
| 7 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 3833 | 0.033 | 0.0024 | No |
| 8 | AGXT | AGXT Entrez, Source | alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) | 4309 | 0.025 | -0.0249 | No |
| 9 | CHKB | CHKB Entrez, Source | choline kinase beta | 5538 | 0.008 | -0.1147 | No |
| 10 | PHGDH | PHGDH Entrez, Source | phosphoglycerate dehydrogenase | 5695 | 0.006 | -0.1245 | No |
| 11 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 6337 | -0.002 | -0.1719 | No |
| 12 | HSD3B7 | HSD3B7 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 6860 | -0.009 | -0.2082 | No |
| 13 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 6928 | -0.010 | -0.2100 | No |
| 14 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 7106 | -0.012 | -0.2194 | No |
| 15 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 8485 | -0.031 | -0.3128 | No |
| 16 | SARDH | SARDH Entrez, Source | sarcosine dehydrogenase | 8785 | -0.035 | -0.3239 | No |
| 17 | AMT | AMT Entrez, Source | aminomethyltransferase | 9912 | -0.052 | -0.3914 | Yes |
| 18 | AGXT2 | AGXT2 Entrez, Source | alanine-glyoxylate aminotransferase 2 | 10038 | -0.054 | -0.3829 | Yes |
| 19 | RDH11 | RDH11 Entrez, Source | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 10096 | -0.055 | -0.3691 | Yes |
| 20 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 10295 | -0.058 | -0.3648 | Yes |
| 21 | PEMT | PEMT Entrez, Source | phosphatidylethanolamine N-methyltransferase | 10459 | -0.061 | -0.3568 | Yes |
| 22 | CHKA | CHKA Entrez, Source | choline kinase alpha | 10678 | -0.066 | -0.3515 | Yes |
| 23 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 11324 | -0.082 | -0.3730 | Yes |
| 24 | TARS | TARS Entrez, Source | threonyl-tRNA synthetase | 11414 | -0.084 | -0.3519 | Yes |
| 25 | AKR1B10 | AKR1B10 Entrez, Source | aldo-keto reductase family 1, member B10 (aldose reductase) | 11557 | -0.088 | -0.3336 | Yes |
| 26 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 11841 | -0.097 | -0.3229 | Yes |
| 27 | PSAT1 | PSAT1 Entrez, Source | phosphoserine aminotransferase 1 | 12104 | -0.107 | -0.3072 | Yes |
| 28 | SHMT2 | SHMT2 Entrez, Source | serine hydroxymethyltransferase 2 (mitochondrial) | 12164 | -0.110 | -0.2754 | Yes |
| 29 | CTH | CTH Entrez, Source | cystathionase (cystathionine gamma-lyase) | 12543 | -0.131 | -0.2606 | Yes |
| 30 | SHMT1 | SHMT1 Entrez, Source | serine hydroxymethyltransferase 1 (soluble) | 12628 | -0.136 | -0.2221 | Yes |
| 31 | GAMT | GAMT Entrez, Source | guanidinoacetate N-methyltransferase | 12960 | -0.175 | -0.1895 | Yes |
| 32 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 12987 | -0.180 | -0.1321 | Yes |
| 33 | GCAT | GCAT Entrez, Source | glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase) | 13084 | -0.205 | -0.0718 | Yes |
| 34 | PSPH | PSPH Entrez, Source | phosphoserine phosphatase | 13229 | -0.277 | 0.0085 | Yes |
