Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | HSA00790_FOLATE_BIOSYNTHESIS |
| Enrichment Score (ES) | -0.632425 |
| Normalized Enrichment Score (NES) | -1.7629392 |
| Nominal p-value | 0.0021505377 |
| FDR q-value | 0.15559667 |
| FWER p-Value | 0.976 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ALPI | ALPI Entrez, Source | alkaline phosphatase, intestinal | 5194 | 0.013 | -0.3802 | No |
| 2 | ERCC3 | ERCC3 Entrez, Source | excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) | 5284 | 0.011 | -0.3783 | No |
| 3 | DDX50 | DDX50 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | 6275 | -0.002 | -0.4513 | No |
| 4 | SMARCA2 | SMARCA2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 6971 | -0.010 | -0.4957 | No |
| 5 | DDX47 | DDX47 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 | 7436 | -0.016 | -0.5185 | No |
| 6 | ALPL | ALPL Entrez, Source | alkaline phosphatase, liver/bone/kidney | 7438 | -0.016 | -0.5065 | No |
| 7 | DDX52 | DDX52 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 | 8560 | -0.032 | -0.5666 | No |
| 8 | PTS | PTS Entrez, Source | 6-pyruvoyltetrahydropterin synthase | 8826 | -0.035 | -0.5598 | No |
| 9 | SPR | SPR Entrez, Source | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 9360 | -0.043 | -0.5674 | No |
| 10 | RUVBL2 | RUVBL2 Entrez, Source | RuvB-like 2 (E. coli) | 10227 | -0.057 | -0.5891 | Yes |
| 11 | DDX56 | DDX56 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 | 10784 | -0.068 | -0.5792 | Yes |
| 12 | DDX18 | DDX18 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 11433 | -0.085 | -0.5636 | Yes |
| 13 | DHFR | DHFR Entrez, Source | dihydrofolate reductase | 11751 | -0.094 | -0.5163 | Yes |
| 14 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 12067 | -0.106 | -0.4599 | Yes |
| 15 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12441 | -0.123 | -0.3944 | Yes |
| 16 | NUDT5 | NUDT5 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 5 | 12497 | -0.127 | -0.3018 | Yes |
| 17 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 12570 | -0.133 | -0.2065 | Yes |
| 18 | EP400 | EP400 Entrez, Source | E1A binding protein p400 | 12926 | -0.168 | -0.1056 | Yes |
| 19 | ASCC3L1 | ASCC3L1 Entrez, Source | activating signal cointegrator 1 complex subunit 3-like 1 | 12985 | -0.180 | 0.0268 | Yes |
