Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA01430_CELL_COMMUNICATION |
| Enrichment Score (ES) | 0.73702466 |
| Normalized Enrichment Score (NES) | 2.3760314 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 3 | 1.046 | 0.1238 | Yes |
| 2 | VIM | VIM Entrez, Source | vimentin | 6 | 0.953 | 0.2367 | Yes |
| 3 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 14 | 0.770 | 0.3276 | Yes |
| 4 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 15 | 0.737 | 0.4150 | Yes |
| 5 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 28 | 0.668 | 0.4934 | Yes |
| 6 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 50 | 0.578 | 0.5603 | Yes |
| 7 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 121 | 0.401 | 0.6026 | Yes |
| 8 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 196 | 0.324 | 0.6354 | Yes |
| 9 | LAMC1 | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 224 | 0.303 | 0.6693 | Yes |
| 10 | GJB5 | GJB5 Entrez, Source | gap junction protein, beta 5 (connexin 31.1) | 322 | 0.239 | 0.6904 | Yes |
| 11 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 351 | 0.229 | 0.7155 | Yes |
| 12 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 460 | 0.193 | 0.7302 | Yes |
| 13 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 738 | 0.146 | 0.7266 | Yes |
| 14 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 1105 | 0.114 | 0.7127 | Yes |
| 15 | COL4A4 | COL4A4 Entrez, Source | collagen, type IV, alpha 4 | 1373 | 0.100 | 0.7045 | Yes |
| 16 | GJB1 | GJB1 Entrez, Source | gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked) | 1380 | 0.100 | 0.7158 | Yes |
| 17 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 1404 | 0.098 | 0.7257 | Yes |
| 18 | DES | DES Entrez, Source | desmin | 1409 | 0.098 | 0.7370 | Yes |
| 19 | NES | NES Entrez, Source | nestin | 2342 | 0.063 | 0.6744 | No |
| 20 | COL11A1 | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 2472 | 0.060 | 0.6719 | No |
| 21 | FN1 | FN1 Entrez, Source | fibronectin 1 | 2637 | 0.057 | 0.6663 | No |
| 22 | THBS4 | THBS4 Entrez, Source | thrombospondin 4 | 2746 | 0.054 | 0.6646 | No |
| 23 | GJB3 | GJB3 Entrez, Source | gap junction protein, beta 3, 31kDa (connexin 31) | 2912 | 0.051 | 0.6581 | No |
| 24 | GJB4 | GJB4 Entrez, Source | gap junction protein, beta 4 (connexin 30.3) | 3665 | 0.036 | 0.6058 | No |
| 25 | IBSP | IBSP Entrez, Source | integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II) | 3929 | 0.031 | 0.5898 | No |
| 26 | ACTB | ACTB Entrez, Source | actin, beta | 4714 | 0.019 | 0.5331 | No |
| 27 | VTN | VTN Entrez, Source | vitronectin | 5129 | 0.014 | 0.5036 | No |
| 28 | RELN | RELN Entrez, Source | reelin | 5458 | 0.009 | 0.4799 | No |
| 29 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 5569 | 0.007 | 0.4725 | No |
| 30 | LMNA | LMNA Entrez, Source | lamin A/C | 5805 | 0.004 | 0.4554 | No |
| 31 | DSC2 | DSC2 Entrez, Source | desmocollin 2 | 6067 | 0.001 | 0.4359 | No |
| 32 | KRT25 | KRT25 Entrez, Source | keratin 25 | 6092 | 0.001 | 0.4342 | No |
| 33 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 6323 | -0.002 | 0.4172 | No |
| 34 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 6404 | -0.003 | 0.4115 | No |
| 35 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 6967 | -0.010 | 0.3705 | No |
| 36 | KRT20 | KRT20 Entrez, Source | keratin 20 | 7155 | -0.013 | 0.3579 | No |
| 37 | LAMA5 | LAMA5 Entrez, Source | laminin, alpha 5 | 7254 | -0.014 | 0.3521 | No |
| 38 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 7411 | -0.015 | 0.3422 | No |
| 39 | GJA3 | GJA3 Entrez, Source | gap junction protein, alpha 3, 46kDa (connexin 46) | 7759 | -0.020 | 0.3185 | No |
| 40 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 8471 | -0.031 | 0.2687 | No |
| 41 | VWF | VWF Entrez, Source | von Willebrand factor | 9242 | -0.041 | 0.2156 | No |
| 42 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 9270 | -0.041 | 0.2185 | No |
| 43 | GJA5 | GJA5 Entrez, Source | gap junction protein, alpha 5, 40kDa (connexin 40) | 9982 | -0.053 | 0.1713 | No |
| 44 | COMP | COMP Entrez, Source | cartilage oligomeric matrix protein | 10344 | -0.059 | 0.1511 | No |
| 45 | TNR | TNR Entrez, Source | tenascin R (restrictin, janusin) | 11126 | -0.076 | 0.1015 | No |
| 46 | CHAD | CHAD Entrez, Source | chondroadherin | 11454 | -0.085 | 0.0870 | No |
| 47 | GJB6 | GJB6 Entrez, Source | gap junction protein, beta 6 (connexin 30) | 11891 | -0.099 | 0.0659 | No |
| 48 | GJB2 | GJB2 Entrez, Source | gap junction protein, beta 2, 26kDa (connexin 26) | 12323 | -0.117 | 0.0474 | No |
| 49 | COL5A3 | COL5A3 Entrez, Source | collagen, type V, alpha 3 | 13187 | -0.246 | 0.0117 | No |
