Details for gene set HYPOXIA_NORMAL

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in class	double_gel_8d
GeneSet	HYPOXIA_NORMAL_UP
Enrichment Score (ES)	0.4995823
Normalized Enrichment Score (NES)	1.8623369
Nominal p-value	0.0
FDR q-value	0.021877332
FWER p-Value	0.812

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SERPINE1	SERPINE1 Entrez, Source	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	12	0.803	0.0640	Yes
2	CORO1A	CORO1A Entrez, Source	coronin, actin binding protein, 1A	41	0.620	0.1120	Yes
3	GPRC5A	GPRC5A Entrez, Source	G protein-coupled receptor, family C, group 5, member A	49	0.587	0.1590	Yes
4	LOX	LOX Entrez, Source	lysyl oxidase	82	0.465	0.1942	Yes
5	ITGB4	ITGB4 Entrez, Source	integrin, beta 4	121	0.401	0.2238	Yes
6	CITED2	CITED2 Entrez, Source	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	145	0.367	0.2517	Yes
7	ANGPTL4	ANGPTL4 Entrez, Source	angiopoietin-like 4	147	0.365	0.2811	Yes
8	TSC22D3	TSC22D3 Entrez, Source	TSC22 domain family, member 3	276	0.263	0.2927	Yes
9	CD9	CD9 Entrez, Source	CD9 molecule	299	0.250	0.3113	Yes
10	NOL3	NOL3 Entrez, Source	nucleolar protein 3 (apoptosis repressor with CARD domain)	325	0.238	0.3286	Yes
11	CFD	CFD Entrez, Source	complement factor D (adipsin)	337	0.234	0.3467	Yes
12	KLF6	KLF6 Entrez, Source	Kruppel-like factor 6	364	0.225	0.3629	Yes
13	FEZ1	FEZ1 Entrez, Source	fasciculation and elongation protein zeta 1 (zygin I)	468	0.190	0.3705	Yes
14	SGCE	SGCE Entrez, Source	sarcoglycan, epsilon	484	0.185	0.3843	Yes
15	CLDN3	CLDN3 Entrez, Source	claudin 3	504	0.181	0.3976	Yes
16	IFNGR1	IFNGR1 Entrez, Source	interferon gamma receptor 1	529	0.177	0.4101	Yes
17	ADFP	ADFP Entrez, Source	adipose differentiation-related protein	550	0.172	0.4225	Yes
18	CPD	CPD Entrez, Source	carboxypeptidase D	565	0.171	0.4352	Yes
19	IGFBP3	IGFBP3 Entrez, Source	insulin-like growth factor binding protein 3	567	0.170	0.4489	Yes
20	ANXA4	ANXA4 Entrez, Source	annexin A4	722	0.148	0.4492	Yes
21	KHDRBS3	KHDRBS3 Entrez, Source	KH domain containing, RNA binding, signal transduction associated 3	745	0.145	0.4593	Yes
22	NFKBIA	NFKBIA Entrez, Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	888	0.130	0.4591	Yes
23	YPEL5	YPEL5 Entrez, Source	yippee-like 5 (Drosophila)	1026	0.119	0.4583	Yes
24	GADD45B	GADD45B Entrez, Source	growth arrest and DNA-damage-inducible, beta	1045	0.118	0.4665	Yes
25	CHPT1	CHPT1 Entrez, Source	choline phosphotransferase 1	1080	0.116	0.4733	Yes
26	BNIP3	BNIP3 Entrez, Source	BCL2/adenovirus E1B 19kDa interacting protein 3	1177	0.111	0.4750	Yes
27	SLC2A1	SLC2A1 Entrez, Source	solute carrier family 2 (facilitated glucose transporter), member 1	1212	0.109	0.4812	Yes
28	CKB	CKB Entrez, Source	creatine kinase, brain	1226	0.108	0.4890	Yes
29	DUSP1	DUSP1 Entrez, Source	dual specificity phosphatase 1	1297	0.104	0.4921	Yes
30	ZFP36L1	ZFP36L1 Entrez, Source	zinc finger protein 36, C3H type-like 1	1350	0.101	0.4964	Yes
31	MFGE8	MFGE8 Entrez, Source	milk fat globule-EGF factor 8 protein	1496	0.094	0.4930	Yes
32	CAPG	CAPG Entrez, Source	capping protein (actin filament), gelsolin-like	1510	0.093	0.4996	Yes
33	BNIP3L	BNIP3L Entrez, Source	BCL2/adenovirus E1B 19kDa interacting protein 3-like	1863	0.078	0.4792	No
34	PLCD1	PLCD1 Entrez, Source	phospholipase C, delta 1	1899	0.077	0.4828	No
35	STC2	STC2 Entrez, Source	stanniocalcin 2	2009	0.073	0.4804	No
36	VAPB	VAPB Entrez, Source	VAMP (vesicle-associated membrane protein)-associated protein B and C	2232	0.066	0.4690	No
37	SLIT1	SLIT1 Entrez, Source	slit homolog 1 (Drosophila)	2578	0.058	0.4476	No
38	MYOD1	MYOD1 Entrez, Source	myogenic differentiation 1	2669	0.056	0.4452	No
39	RALGDS	RALGDS Entrez, Source	ral guanine nucleotide dissociation stimulator	2700	0.055	0.4474	No
40	IL9R	IL9R Entrez, Source	interleukin 9 receptor	2818	0.052	0.4428	No
41	NIT1	NIT1 Entrez, Source	nitrilase 1	2859	0.052	0.4440	No
42	LSR	LSR Entrez, Source	lipolysis stimulated lipoprotein receptor	2866	0.051	0.4477	No
43	ARL1	ARL1 Entrez, Source	ADP-ribosylation factor-like 1	2908	0.051	0.4487	No
44	H3F3B	H3F3B Entrez, Source	H3 histone, family 3B (H3.3B)	3095	0.047	0.4384	No
45	TIMP1	TIMP1 Entrez, Source	TIMP metallopeptidase inhibitor 1	3256	0.044	0.4298	No
46	UPP1	UPP1 Entrez, Source	uridine phosphorylase 1	3489	0.039	0.4153	No
47	PDGFC	PDGFC Entrez, Source	platelet derived growth factor C	3584	0.037	0.4112	No
48	TMEM30A	TMEM30A Entrez, Source	transmembrane protein 30A	3803	0.033	0.3974	No
49	BSG	BSG Entrez, Source	basigin (Ok blood group)	3928	0.031	0.3906	No
50	SNX10	SNX10 Entrez, Source	sorting nexin 10	3945	0.031	0.3919	No
51	RNF146	RNF146 Entrez, Source	ring finger protein 146	4005	0.030	0.3899	No
52	MESDC1	MESDC1 Entrez, Source	mesoderm development candidate 1	4058	0.029	0.3883	No
53	SDCBP	SDCBP Entrez, Source	syndecan binding protein (syntenin)	4064	0.029	0.3903	No
54	STXBP2	STXBP2 Entrez, Source	syntaxin binding protein 2	4370	0.024	0.3692	No
55	ADAM10	ADAM10 Entrez, Source	ADAM metallopeptidase domain 10	4533	0.022	0.3587	No
56	NDUFA5	NDUFA5 Entrez, Source	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa	4637	0.020	0.3525	No
57	TOMM20	TOMM20 Entrez, Source	translocase of outer mitochondrial membrane 20 homolog (yeast)	4757	0.019	0.3451	No
58	DDX19B	DDX19B Entrez, Source	DEAD (Asp-Glu-Ala-As) box polypeptide 19B	4858	0.017	0.3389	No
59	HIF1A	HIF1A Entrez, Source	hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	4892	0.017	0.3378	No
60	NMT1	NMT1 Entrez, Source	N-myristoyltransferase 1	4905	0.017	0.3382	No
61	SCD	SCD Entrez, Source	stearoyl-CoA desaturase (delta-9-desaturase)	5035	0.015	0.3296	No
62	STAMBP	STAMBP Entrez, Source	STAM binding protein	5159	0.013	0.3214	No
63	PJA2	PJA2 Entrez, Source	praja 2, RING-H2 motif containing	5198	0.013	0.3195	No
64	CDC42	CDC42 Entrez, Source	cell division cycle 42 (GTP binding protein, 25kDa)	5202	0.013	0.3203	No
65	SPATA20	SPATA20 Entrez, Source	spermatogenesis associated 20	5270	0.011	0.3162	No
66	MAP2K6	MAP2K6 Entrez, Source	mitogen-activated protein kinase kinase 6	5505	0.008	0.2991	No
67	AP3M2	AP3M2 Entrez, Source	adaptor-related protein complex 3, mu 2 subunit	5555	0.007	0.2960	No
68	ALDOC	ALDOC Entrez, Source	aldolase C, fructose-bisphosphate	5585	0.007	0.2944	No
69	STOM	STOM Entrez, Source	stomatin	5982	0.002	0.2646	No
70	IFI30	IFI30 Entrez, Source	interferon, gamma-inducible protein 30	6191	-0.000	0.2489	No
71	ATP1B3	ATP1B3 Entrez, Source	ATPase, Na+/K+ transporting, beta 3 polypeptide	6301	-0.002	0.2409	No
72	MAPK7	MAPK7 Entrez, Source	mitogen-activated protein kinase 7	6376	-0.003	0.2355	No
73	KCMF1	KCMF1 Entrez, Source	potassium channel modulatory factor 1	6430	-0.004	0.2317	No
74	SYF2	SYF2 Entrez, Source	SYF2 homolog, RNA splicing factor (S. cerevisiae)	6446	-0.004	0.2309	No
75	CANX	CANX Entrez, Source	calnexin	6492	-0.004	0.2279	No
76	HSPA5	HSPA5 Entrez, Source	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	6557	-0.005	0.2234	No
77	HEMGN	HEMGN Entrez, Source	hemogen	6620	-0.006	0.2192	No
78	NDRG1	NDRG1 Entrez, Source	N-myc downstream regulated gene 1	6962	-0.010	0.1942	No
79	TFG	TFG Entrez, Source	TRK-fused gene	7017	-0.011	0.1910	No
80	ACTC1	ACTC1 Entrez, Source	actin, alpha, cardiac muscle 1	7393	-0.015	0.1639	No
81	AKAP12	AKAP12 Entrez, Source	A kinase (PRKA) anchor protein (gravin) 12	7409	-0.015	0.1640	No
82	UGCG	UGCG Entrez, Source	UDP-glucose ceramide glucosyltransferase	7435	-0.016	0.1634	No
83	ALPL	ALPL Entrez, Source	alkaline phosphatase, liver/bone/kidney	7438	-0.016	0.1645	No
84	MTUS1	MTUS1 Entrez, Source	mitochondrial tumor suppressor 1	7445	-0.016	0.1654	No
85	GRSF1	GRSF1 Entrez, Source	G-rich RNA sequence binding factor 1	7484	-0.016	0.1638	No
86	SERTAD2	SERTAD2 Entrez, Source	SERTA domain containing 2	7501	-0.017	0.1640	No
87	RFX3	RFX3 Entrez, Source	regulatory factor X, 3 (influences HLA class II expression)	7612	-0.018	0.1571	No
88	HOOK2	HOOK2 Entrez, Source	hook homolog 2 (Drosophila)	7713	-0.020	0.1511	No
89	SYT13	SYT13 Entrez, Source	synaptotagmin XIII	7782	-0.021	0.1476	No
90	PTPRU	PTPRU Entrez, Source	protein tyrosine phosphatase, receptor type, U	7795	-0.021	0.1484	No
91	ADD3	ADD3 Entrez, Source	adducin 3 (gamma)	7901	-0.022	0.1422	No
92	NEK6	NEK6 Entrez, Source	NIMA (never in mitosis gene a)-related kinase 6	8247	-0.027	0.1183	No
93	STAU1	STAU1 Entrez, Source	staufen, RNA binding protein, homolog 1 (Drosophila)	8255	-0.027	0.1200	No
94	EIF2S2	EIF2S2 Entrez, Source	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa	8326	-0.028	0.1170	No
95	PSMD6	PSMD6 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	8376	-0.029	0.1156	No
96	MVK	MVK Entrez, Source	mevalonate kinase (mevalonic aciduria)	8632	-0.033	0.0989	No
97	KCNMA1	KCNMA1 Entrez, Source	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	8797	-0.035	0.0893	No
98	ADAR	ADAR Entrez, Source	adenosine deaminase, RNA-specific	8925	-0.036	0.0827	No
99	SERBP1	SERBP1 Entrez, Source	SERPINE1 mRNA binding protein 1	8948	-0.037	0.0840	No
100	TRSPAP1	TRSPAP1 Entrez, Source	tRNA selenocysteine associated protein 1	8952	-0.037	0.0868	No
101	FBXL10	FBXL10 Entrez, Source	F-box and leucine-rich repeat protein 10	9032	-0.038	0.0839	No
102	XPNPEP1	XPNPEP1 Entrez, Source	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	9226	-0.041	0.0725	No
103	PTPN12	PTPN12 Entrez, Source	protein tyrosine phosphatase, non-receptor type 12	9303	-0.042	0.0702	No
104	DHCR7	DHCR7 Entrez, Source	7-dehydrocholesterol reductase	9455	-0.044	0.0623	No
105	SQLE	SQLE Entrez, Source	squalene epoxidase	9644	-0.048	0.0519	No
106	TGM2	TGM2 Entrez, Source	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	9694	-0.049	0.0521	No
107	PRODH	PRODH Entrez, Source	proline dehydrogenase (oxidase) 1	9764	-0.050	0.0509	No
108	HLF	HLF Entrez, Source	hepatic leukemia factor	9889	-0.052	0.0457	No
109	NARS	NARS Entrez, Source	asparaginyl-tRNA synthetase	10017	-0.054	0.0405	No
110	FBXO8	FBXO8 Entrez, Source	F-box protein 8	10173	-0.056	0.0333	No
111	ARHGEF2	ARHGEF2 Entrez, Source	rho/rac guanine nucleotide exchange factor (GEF) 2	10190	-0.057	0.0367	No
112	LRP1	LRP1 Entrez, Source	low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)	10559	-0.063	0.0139	No
113	P4HB	P4HB Entrez, Source	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide	10713	-0.066	0.0077	No
114	PFKFB4	PFKFB4 Entrez, Source	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	10770	-0.068	0.0090	No
115	EXOSC7	EXOSC7 Entrez, Source	exosome component 7	10861	-0.070	0.0078	No
116	MDK	MDK Entrez, Source	midkine (neurite growth-promoting factor 2)	10954	-0.072	0.0067	No
117	TCEA3	TCEA3 Entrez, Source	transcription elongation factor A (SII), 3	11146	-0.077	-0.0015	No
118	SC4MOL	SC4MOL Entrez, Source	sterol-C4-methyl oxidase-like	11182	-0.078	0.0021	No
119	NT5E	NT5E Entrez, Source	5'-nucleotidase, ecto (CD73)	11299	-0.081	-0.0001	No
120	SNTA1	SNTA1 Entrez, Source	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	11602	-0.089	-0.0158	No
121	UGP2	UGP2 Entrez, Source	UDP-glucose pyrophosphorylase 2	11694	-0.092	-0.0152	No
122	SIRPA	SIRPA Entrez, Source	signal-regulatory protein alpha	11784	-0.095	-0.0143	No
123	KPNB1	KPNB1 Entrez, Source	karyopherin (importin) beta 1	11995	-0.103	-0.0219	No
124	HMOX1	HMOX1 Entrez, Source	heme oxygenase (decycling) 1	12319	-0.117	-0.0369	No
125	GTPBP2	GTPBP2 Entrez, Source	GTP binding protein 2	12459	-0.124	-0.0374	No
126	GM2A	GM2A Entrez, Source	GM2 ganglioside activator	12760	-0.148	-0.0481	No
127	SLC3A2	SLC3A2 Entrez, Source	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	13019	-0.189	-0.0524	No
128	SLC30A1	SLC30A1 Entrez, Source	solute carrier family 30 (zinc transporter), member 1	13228	-0.276	-0.0458	No
129	FASN	FASN Entrez, Source	fatty acid synthase	13241	-0.288	-0.0234	No
130	PPP1R3C	PPP1R3C Entrez, Source	protein phosphatase 1, regulatory (inhibitor) subunit 3C	13293	-0.383	0.0037	No