Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | HYPOXIA_RCC_UP |
| Enrichment Score (ES) | -0.36596867 |
| Normalized Enrichment Score (NES) | -1.2863089 |
| Nominal p-value | 0.11401425 |
| FDR q-value | 0.5690442 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 1045 | 0.118 | -0.0437 | No |
| 2 | HIRIP3 | HIRIP3 Entrez, Source | HIRA interacting protein 3 | 1048 | 0.118 | -0.0089 | No |
| 3 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 1333 | 0.102 | 0.0000 | No |
| 4 | KIFC3 | KIFC3 Entrez, Source | kinesin family member C3 | 1724 | 0.084 | -0.0045 | No |
| 5 | CD276 | CD276 Entrez, Source | CD276 molecule | 2055 | 0.071 | -0.0083 | No |
| 6 | DPM2 | DPM2 Entrez, Source | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit | 2411 | 0.062 | -0.0167 | No |
| 7 | PRPF19 | PRPF19 Entrez, Source | PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) | 2625 | 0.057 | -0.0158 | No |
| 8 | RAB14 | RAB14 Entrez, Source | RAB14, member RAS oncogene family | 2806 | 0.053 | -0.0137 | No |
| 9 | TES | TES Entrez, Source | testis derived transcript (3 LIM domains) | 3036 | 0.048 | -0.0168 | No |
| 10 | MRPL41 | MRPL41 Entrez, Source | mitochondrial ribosomal protein L41 | 3076 | 0.047 | -0.0058 | No |
| 11 | GTF2A2 | GTF2A2 Entrez, Source | general transcription factor IIA, 2, 12kDa | 3615 | 0.037 | -0.0354 | No |
| 12 | RHOT2 | RHOT2 Entrez, Source | ras homolog gene family, member T2 | 3862 | 0.032 | -0.0443 | No |
| 13 | PPM1F | PPM1F Entrez, Source | protein phosphatase 1F (PP2C domain containing) | 4026 | 0.030 | -0.0477 | No |
| 14 | PECR | PECR Entrez, Source | peroxisomal trans-2-enoyl-CoA reductase | 4812 | 0.018 | -0.1014 | No |
| 15 | SSU72 | SSU72 Entrez, Source | SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) | 4943 | 0.016 | -0.1065 | No |
| 16 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 5266 | 0.012 | -0.1273 | No |
| 17 | ATP5G3 | ATP5G3 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) | 5742 | 0.005 | -0.1615 | No |
| 18 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 6464 | -0.004 | -0.2145 | No |
| 19 | GADD45GIP1 | GADD45GIP1 Entrez, Source | growth arrest and DNA-damage-inducible, gamma interacting protein 1 | 7055 | -0.011 | -0.2556 | No |
| 20 | LRRC48 | LRRC48 Entrez, Source | leucine rich repeat containing 48 | 7446 | -0.016 | -0.2802 | No |
| 21 | GMFB | GMFB Entrez, Source | glia maturation factor, beta | 7835 | -0.021 | -0.3031 | No |
| 22 | YIPF5 | YIPF5 Entrez, Source | Yip1 domain family, member 5 | 7900 | -0.022 | -0.3014 | No |
| 23 | APLP2 | APLP2 Entrez, Source | amyloid beta (A4) precursor-like protein 2 | 7920 | -0.022 | -0.2962 | No |
| 24 | WDR6 | WDR6 Entrez, Source | WD repeat domain 6 | 8108 | -0.025 | -0.3028 | No |
| 25 | SERBP1 | SERBP1 Entrez, Source | SERPINE1 mRNA binding protein 1 | 8948 | -0.037 | -0.3550 | Yes |
| 26 | TRSPAP1 | TRSPAP1 Entrez, Source | tRNA selenocysteine associated protein 1 | 8952 | -0.037 | -0.3443 | Yes |
| 27 | ARF5 | ARF5 Entrez, Source | ADP-ribosylation factor 5 | 9169 | -0.040 | -0.3487 | Yes |
| 28 | TMEM5 | TMEM5 Entrez, Source | transmembrane protein 5 | 9173 | -0.040 | -0.3371 | Yes |
| 29 | RPL3 | RPL3 Entrez, Source | ribosomal protein L3 | 9257 | -0.041 | -0.3312 | Yes |
| 30 | GNG12 | GNG12 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 12 | 9617 | -0.047 | -0.3441 | Yes |
| 31 | RPL37 | RPL37 Entrez, Source | ribosomal protein L37 | 9799 | -0.050 | -0.3429 | Yes |
| 32 | MRPL13 | MRPL13 Entrez, Source | mitochondrial ribosomal protein L13 | 9917 | -0.052 | -0.3362 | Yes |
| 33 | RPS15A | RPS15A Entrez, Source | ribosomal protein S15a | 10118 | -0.055 | -0.3348 | Yes |
| 34 | EWSR1 | EWSR1 Entrez, Source | Ewing sarcoma breakpoint region 1 | 10419 | -0.061 | -0.3394 | Yes |
| 35 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 10434 | -0.061 | -0.3224 | Yes |
| 36 | PARL | PARL Entrez, Source | presenilin associated, rhomboid-like | 10455 | -0.061 | -0.3057 | Yes |
| 37 | METTL3 | METTL3 Entrez, Source | methyltransferase like 3 | 10544 | -0.063 | -0.2936 | Yes |
| 38 | CNTN5 | CNTN5 Entrez, Source | contactin 5 | 10556 | -0.063 | -0.2756 | Yes |
| 39 | CAND1 | CAND1 Entrez, Source | cullin-associated and neddylation-dissociated 1 | 10608 | -0.065 | -0.2603 | Yes |
| 40 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10927 | -0.072 | -0.2631 | Yes |
| 41 | SCYE1 | SCYE1 Entrez, Source | small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) | 11138 | -0.077 | -0.2561 | Yes |
| 42 | PPP2R5D | PPP2R5D Entrez, Source | protein phosphatase 2, regulatory subunit B (B56), delta isoform | 11192 | -0.078 | -0.2369 | Yes |
| 43 | CTSC | CTSC Entrez, Source | cathepsin C | 11373 | -0.083 | -0.2258 | Yes |
| 44 | PDLIM7 | PDLIM7 Entrez, Source | PDZ and LIM domain 7 (enigma) | 11377 | -0.083 | -0.2012 | Yes |
| 45 | CEACAM1 | CEACAM1 Entrez, Source | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 11634 | -0.090 | -0.1939 | Yes |
| 46 | RPL22 | RPL22 Entrez, Source | ribosomal protein L22 | 12075 | -0.106 | -0.1956 | Yes |
| 47 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 12159 | -0.110 | -0.1692 | Yes |
| 48 | SCARB2 | SCARB2 Entrez, Source | scavenger receptor class B, member 2 | 12277 | -0.115 | -0.1440 | Yes |
| 49 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12447 | -0.123 | -0.1201 | Yes |
| 50 | SLC3A2 | SLC3A2 Entrez, Source | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 13019 | -0.189 | -0.1070 | Yes |
| 51 | RPL39 | RPL39 Entrez, Source | ribosomal protein L39 | 13115 | -0.215 | -0.0505 | Yes |
| 52 | KIF1B | KIF1B Entrez, Source | kinesin family member 1B | 13158 | -0.228 | 0.0138 | Yes |
