Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | IDX_TSA_DN_CLUSTER2 |
| Enrichment Score (ES) | 0.5592467 |
| Normalized Enrichment Score (NES) | 1.7933515 |
| Nominal p-value | 0.0017953322 |
| FDR q-value | 0.033134762 |
| FWER p-Value | 0.974 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LOX | LOX Entrez, Source | lysyl oxidase | 82 | 0.465 | 0.0813 | Yes |
| 2 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 89 | 0.456 | 0.1666 | Yes |
| 3 | PGCP | PGCP Entrez, Source | - | 159 | 0.356 | 0.2283 | Yes |
| 4 | FXYD5 | FXYD5 Entrez, Source | FXYD domain containing ion transport regulator 5 | 217 | 0.309 | 0.2822 | Yes |
| 5 | MSN | MSN Entrez, Source | moesin | 248 | 0.285 | 0.3336 | Yes |
| 6 | PRSS23 | PRSS23 Entrez, Source | protease, serine, 23 | 251 | 0.281 | 0.3863 | Yes |
| 7 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 358 | 0.227 | 0.4210 | Yes |
| 8 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 697 | 0.150 | 0.4239 | Yes |
| 9 | PDPN | PDPN Entrez, Source | podoplanin | 724 | 0.148 | 0.4497 | Yes |
| 10 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 1062 | 0.117 | 0.4462 | Yes |
| 11 | ZFP36L2 | ZFP36L2 Entrez, Source | zinc finger protein 36, C3H type-like 2 | 1206 | 0.109 | 0.4561 | Yes |
| 12 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 1267 | 0.106 | 0.4714 | Yes |
| 13 | TMSB10 | TMSB10 Entrez, Source | thymosin, beta 10 | 1292 | 0.105 | 0.4893 | Yes |
| 14 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 1439 | 0.096 | 0.4965 | Yes |
| 15 | PLD3 | PLD3 Entrez, Source | phospholipase D family, member 3 | 1454 | 0.096 | 0.5135 | Yes |
| 16 | LAMP2 | LAMP2 Entrez, Source | lysosomal-associated membrane protein 2 | 1467 | 0.095 | 0.5305 | Yes |
| 17 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 1510 | 0.093 | 0.5450 | Yes |
| 18 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 1550 | 0.092 | 0.5592 | Yes |
| 19 | CD276 | CD276 Entrez, Source | CD276 molecule | 2055 | 0.071 | 0.5347 | No |
| 20 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 2842 | 0.052 | 0.4853 | No |
| 21 | SCPEP1 | SCPEP1 Entrez, Source | serine carboxypeptidase 1 | 2876 | 0.051 | 0.4925 | No |
| 22 | TES | TES Entrez, Source | testis derived transcript (3 LIM domains) | 3036 | 0.048 | 0.4895 | No |
| 23 | SERTAD1 | SERTAD1 Entrez, Source | SERTA domain containing 1 | 3172 | 0.045 | 0.4878 | No |
| 24 | MAP1LC3B | MAP1LC3B Entrez, Source | microtubule-associated protein 1 light chain 3 beta | 3406 | 0.040 | 0.4779 | No |
| 25 | LEPROT | LEPROT Entrez, Source | leptin receptor overlapping transcript | 3656 | 0.036 | 0.4659 | No |
| 26 | SLC38A4 | SLC38A4 Entrez, Source | solute carrier family 38, member 4 | 3698 | 0.035 | 0.4695 | No |
| 27 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 3736 | 0.035 | 0.4732 | No |
| 28 | TWIST2 | TWIST2 Entrez, Source | twist homolog 2 (Drosophila) | 3829 | 0.033 | 0.4725 | No |
| 29 | CD99 | CD99 Entrez, Source | CD99 molecule | 3891 | 0.032 | 0.4739 | No |
| 30 | ASAH1 | ASAH1 Entrez, Source | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 3904 | 0.032 | 0.4790 | No |
| 31 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 5007 | 0.015 | 0.3989 | No |
| 32 | PPGB | PPGB Entrez, Source | protective protein for beta-galactosidase (galactosialidosis) | 5068 | 0.014 | 0.3971 | No |
| 33 | NCAM1 | NCAM1 Entrez, Source | neural cell adhesion molecule 1 | 5249 | 0.012 | 0.3858 | No |
| 34 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 5875 | 0.004 | 0.3395 | No |
| 35 | GNB1 | GNB1 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 7870 | -0.022 | 0.1936 | No |
| 36 | BAX | BAX Entrez, Source | BCL2-associated X protein | 8544 | -0.031 | 0.1488 | No |
| 37 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 8926 | -0.036 | 0.1270 | No |
| 38 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 9012 | -0.038 | 0.1277 | No |
| 39 | SLC1A4 | SLC1A4 Entrez, Source | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 9073 | -0.038 | 0.1305 | No |
| 40 | TINP1 | TINP1 Entrez, Source | - | 9744 | -0.049 | 0.0893 | No |
| 41 | PLXNB2 | PLXNB2 Entrez, Source | plexin B2 | 9773 | -0.050 | 0.0966 | No |
| 42 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 10889 | -0.071 | 0.0260 | No |
| 43 | PDLIM7 | PDLIM7 Entrez, Source | PDZ and LIM domain 7 (enigma) | 11377 | -0.083 | 0.0050 | No |
| 44 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 11781 | -0.095 | -0.0075 | No |
| 45 | TSPAN6 | TSPAN6 Entrez, Source | tetraspanin 6 | 12432 | -0.123 | -0.0333 | No |
| 46 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 12494 | -0.127 | -0.0139 | No |
| 47 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 13085 | -0.205 | -0.0197 | No |
| 48 | NQO2 | NQO2 Entrez, Source | NAD(P)H dehydrogenase, quinone 2 | 13091 | -0.207 | 0.0189 | No |
