Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | IFN_ANY_UP |
| Enrichment Score (ES) | -0.3973855 |
| Normalized Enrichment Score (NES) | -1.3799678 |
| Nominal p-value | 0.056603774 |
| FDR q-value | 0.48643482 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 496 | 0.183 | 0.0107 | No |
| 2 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 772 | 0.143 | 0.0275 | No |
| 3 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 920 | 0.127 | 0.0499 | No |
| 4 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 1327 | 0.103 | 0.0464 | No |
| 5 | BCLAF1 | BCLAF1 Entrez, Source | BCL2-associated transcription factor 1 | 1588 | 0.090 | 0.0504 | No |
| 6 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 1791 | 0.081 | 0.0564 | No |
| 7 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 2190 | 0.067 | 0.0442 | No |
| 8 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 2350 | 0.063 | 0.0489 | No |
| 9 | GMPR | GMPR Entrez, Source | guanosine monophosphate reductase | 2611 | 0.057 | 0.0444 | No |
| 10 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 2697 | 0.055 | 0.0526 | No |
| 11 | SKP1A | SKP1A Entrez, Source | S-phase kinase-associated protein 1A (p19A) | 3287 | 0.043 | 0.0195 | No |
| 12 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 3738 | 0.035 | -0.0052 | No |
| 13 | PPP5C | PPP5C Entrez, Source | protein phosphatase 5, catalytic subunit | 4060 | 0.029 | -0.0217 | No |
| 14 | SDCBP | SDCBP Entrez, Source | syndecan binding protein (syntenin) | 4064 | 0.029 | -0.0142 | No |
| 15 | OAS1 | OAS1 Entrez, Source | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 4150 | 0.028 | -0.0133 | No |
| 16 | CSRP3 | CSRP3 Entrez, Source | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 4369 | 0.024 | -0.0233 | No |
| 17 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 4566 | 0.022 | -0.0324 | No |
| 18 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 4616 | 0.021 | -0.0306 | No |
| 19 | BAK1 | BAK1 Entrez, Source | BCL2-antagonist/killer 1 | 4646 | 0.020 | -0.0274 | No |
| 20 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 4892 | 0.017 | -0.0414 | No |
| 21 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 4953 | 0.016 | -0.0418 | No |
| 22 | COL16A1 | COL16A1 Entrez, Source | collagen, type XVI, alpha 1 | 5051 | 0.015 | -0.0453 | No |
| 23 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 5091 | 0.014 | -0.0445 | No |
| 24 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 5268 | 0.012 | -0.0547 | No |
| 25 | EIF2B1 | EIF2B1 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | 5340 | 0.011 | -0.0573 | No |
| 26 | AP3M2 | AP3M2 Entrez, Source | adaptor-related protein complex 3, mu 2 subunit | 5555 | 0.007 | -0.0714 | No |
| 27 | EPS15 | EPS15 Entrez, Source | epidermal growth factor receptor pathway substrate 15 | 7217 | -0.013 | -0.1929 | No |
| 28 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 7272 | -0.014 | -0.1933 | No |
| 29 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 7318 | -0.014 | -0.1929 | No |
| 30 | GMFB | GMFB Entrez, Source | glia maturation factor, beta | 7835 | -0.021 | -0.2261 | No |
| 31 | FOSL1 | FOSL1 Entrez, Source | FOS-like antigen 1 | 8279 | -0.028 | -0.2522 | No |
| 32 | CTR9 | CTR9 Entrez, Source | Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 8385 | -0.029 | -0.2525 | No |
| 33 | ADAR | ADAR Entrez, Source | adenosine deaminase, RNA-specific | 8925 | -0.036 | -0.2835 | No |
| 34 | PTPN11 | PTPN11 Entrez, Source | protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) | 9881 | -0.052 | -0.3418 | No |
| 35 | MX2 | MX2 Entrez, Source | myxovirus (influenza virus) resistance 2 (mouse) | 10443 | -0.061 | -0.3679 | No |
| 36 | BBC3 | BBC3 Entrez, Source | BCL2 binding component 3 | 10590 | -0.064 | -0.3621 | No |
| 37 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10688 | -0.066 | -0.3520 | No |
| 38 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 10803 | -0.068 | -0.3426 | No |
| 39 | ELF1 | ELF1 Entrez, Source | E74-like factor 1 (ets domain transcription factor) | 11340 | -0.083 | -0.3612 | No |
| 40 | PARP4 | PARP4 Entrez, Source | poly (ADP-ribose) polymerase family, member 4 | 11822 | -0.096 | -0.3721 | Yes |
| 41 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 11880 | -0.098 | -0.3504 | Yes |
| 42 | NMI | NMI Entrez, Source | N-myc (and STAT) interactor | 11925 | -0.100 | -0.3275 | Yes |
| 43 | MAP3K10 | MAP3K10 Entrez, Source | mitogen-activated protein kinase kinase kinase 10 | 12042 | -0.105 | -0.3087 | Yes |
| 44 | ZRF1 | ZRF1 Entrez, Source | zuotin related factor 1 | 12130 | -0.108 | -0.2867 | Yes |
| 45 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 12165 | -0.110 | -0.2603 | Yes |
| 46 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 12268 | -0.115 | -0.2378 | Yes |
| 47 | VAT1 | VAT1 Entrez, Source | vesicle amine transport protein 1 homolog (T californica) | 12333 | -0.118 | -0.2117 | Yes |
| 48 | BST2 | BST2 Entrez, Source | bone marrow stromal cell antigen 2 | 12353 | -0.119 | -0.1819 | Yes |
| 49 | XRCC6 | XRCC6 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) | 12731 | -0.144 | -0.1723 | Yes |
| 50 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 12996 | -0.183 | -0.1440 | Yes |
| 51 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 12999 | -0.184 | -0.0958 | Yes |
| 52 | FUBP1 | FUBP1 Entrez, Source | far upstream element (FUSE) binding protein 1 | 13083 | -0.205 | -0.0481 | Yes |
| 53 | FAS | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 13202 | -0.257 | 0.0105 | Yes |
