Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_8d
GeneSetIGLESIAS_E2FMINUS_UP
Enrichment Score (ES)0.6595451
Normalized Enrichment Score (NES)2.3932543
Nominal p-value0.0
FDR q-value0.0
FWER p-Value0.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: IGLESIAS_E2FMINUS_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 231.0460.0653Yes
2ANXA1ANXA1
Entrez,  Source
annexin A1100.8150.1159Yes
3CCND2CCND2
Entrez,  Source
cyclin D2110.8150.1670Yes
4COL3A1COL3A1
Entrez,  Source
collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)150.7370.2130Yes
5LPLLPL
Entrez,  Source
lipoprotein lipase240.6800.2550Yes
6COL5A2COL5A2
Entrez,  Source
collagen, type V, alpha 2280.6680.2966Yes
7DAB2DAB2
Entrez,  Source
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)310.6610.3379Yes
8EMP1EMP1
Entrez,  Source
epithelial membrane protein 1440.6060.3749Yes
9LGALS1LGALS1
Entrez,  Source
lectin, galactoside-binding, soluble, 1 (galectin 1)470.5970.4122Yes
10COL4A1COL4A1
Entrez,  Source
collagen, type IV, alpha 1500.5780.4482Yes
11SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4560.5620.4830Yes
12SERPINH1SERPINH1
Entrez,  Source
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)1810.3360.4947Yes
13GJA1GJA1
Entrez,  Source
gap junction protein, alpha 1, 43kDa (connexin 43)1960.3240.5139Yes
14SERPINB6A2270.3020.5305Yes
15SPARCSPARC
Entrez,  Source
secreted protein, acidic, cysteine-rich (osteonectin)2340.2970.5487Yes
16CD9CD9
Entrez,  Source
CD9 molecule2990.2500.5595Yes
17CFDCFD
Entrez,  Source
complement factor D (adipsin)3370.2340.5714Yes
18S100A6S100A6
Entrez,  Source
S100 calcium binding protein A64020.2090.5797Yes
19GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)4170.2050.5915Yes
20TMSB4XTMSB4X
Entrez,  Source
thymosin, beta 4, X-linked4270.2020.6034Yes
21COL6A2COL6A2
Entrez,  Source
collagen, type VI, alpha 24600.1930.6131Yes
22IGSF4IGSF4
Entrez,  Source
immunoglobulin superfamily, member 45170.1800.6201Yes
23S100A11S100A11
Entrez,  Source
S100 calcium binding protein A115600.1710.6276Yes
24CTSECTSE
Entrez,  Source
cathepsin E5800.1670.6367Yes
25GNAI2GNAI2
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 26560.1570.6408Yes
26COL1A1COL1A1
Entrez,  Source
collagen, type I, alpha 17380.1460.6438Yes
27RHOBRHOB
Entrez,  Source
ras homolog gene family, member B7850.1410.6492Yes
28NFKBIANFKBIA
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha8880.1300.6496Yes
29ACADLACADL
Entrez,  Source
acyl-Coenzyme A dehydrogenase, long chain8920.1300.6575Yes
30GADD45BGADD45B
Entrez,  Source
growth arrest and DNA-damage-inducible, beta10450.1180.6534Yes
31ANXA3ANXA3
Entrez,  Source
annexin A310620.1170.6595Yes
32ACTA2ACTA2
Entrez,  Source
actin, alpha 2, smooth muscle, aorta14390.0960.6372No
33S100A10S100A10
Entrez,  Source
S100 calcium binding protein A1014440.0960.6429No
34LAPTM4ALAPTM4A
Entrez,  Source
lysosomal-associated protein transmembrane 4 alpha15690.0910.6392No
35CLK1CLK1
Entrez,  Source
CDC-like kinase 115970.0890.6428No
36FBLN2FBLN2
Entrez,  Source
fibulin 217140.0840.6393No
37ANXA2ANXA2
Entrez,  Source
annexin A218250.0790.6359No
38NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)19250.0750.6332No
39ALAS2ALAS2
Entrez,  Source
aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia)21000.0700.6244No
40APOEAPOE
Entrez,  Source
apolipoprotein E23450.0630.6099No
41IGFBP5IGFBP5
Entrez,  Source
insulin-like growth factor binding protein 527130.0550.5856No
42NPTNNPTN
Entrez,  Source
neuroplastin29250.0500.5728No
43DCNDCN
Entrez,  Source
decorin30290.0480.5681No
44NFIBNFIB
Entrez,  Source
nuclear factor I/B30570.0470.5690No
45COL18A1COL18A1
Entrez,  Source
collagen, type XVIII, alpha 132490.0440.5573No
46SS18SS18
Entrez,  Source
synovial sarcoma translocation, chromosome 1832590.0430.5593No
47SKP1ASKP1A
Entrez,  Source
S-phase kinase-associated protein 1A (p19A)32870.0430.5600No
48PMP22PMP22
Entrez,  Source
peripheral myelin protein 2234640.0390.5492No
49CAPZA2CAPZA2
Entrez,  Source
capping protein (actin filament) muscle Z-line, alpha 237500.0340.5298No
50RBBP7RBBP7
Entrez,  Source
retinoblastoma binding protein 737930.0340.5287No
51COL15A1COL15A1
Entrez,  Source
collagen, type XV, alpha 142340.0260.4971No
52CALM2CALM2
Entrez,  Source
calmodulin 2 (phosphorylase kinase, delta)46990.0200.4633No
53LUMLUM
Entrez,  Source
lumican47280.0190.4624No
54ARSAARSA
Entrez,  Source
arylsulfatase A49410.0160.4474No
55B2MB2M
Entrez,  Source
beta-2-microglobulin49920.0150.4445No
56DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)50070.0150.4444No
57CD47CD47
Entrez,  Source
CD47 molecule50660.0140.4410No
58CDC42CDC42
Entrez,  Source
cell division cycle 42 (GTP binding protein, 25kDa)52020.0130.4315No
59ADIPOQADIPOQ
Entrez,  Source
adiponectin, C1Q and collagen domain containing52040.0130.4323No
60TYROBPTYROBP
Entrez,  Source
TYRO protein tyrosine kinase binding protein53880.0100.4191No
61CD53CD53
Entrez,  Source
CD53 molecule55020.0080.4110No
62LMNALMNA
Entrez,  Source
lamin A/C58050.0040.3885No
63PCNAPCNA
Entrez,  Source
proliferating cell nuclear antigen59380.0030.3787No
64NID1NID1
Entrez,  Source
nidogen 161330.0000.3641No
65ITGB1ITGB1
Entrez,  Source
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)6253-0.0010.3552No
66EVLEVL
Entrez,  Source
Enah/Vasp-like6399-0.0030.3444No
67GAS6GAS6
Entrez,  Source
growth arrest-specific 66432-0.0040.3422No
68SMAD1SMAD1
Entrez,  Source
SMAD, mothers against DPP homolog 1 (Drosophila)6658-0.0070.3256No
69ITM2BITM2B
Entrez,  Source
integral membrane protein 2B7038-0.0110.2977No
70LAPTM5LAPTM5
Entrez,  Source
lysosomal associated multispanning membrane protein 57239-0.0140.2834No
71SEPT2SEPT2
Entrez,  Source
septin 27427-0.0160.2703No
72ACADMACADM
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain7437-0.0160.2706No
73MORF4L1MORF4L1
Entrez,  Source
mortality factor 4 like 17518-0.0170.2656No
74HBA-A17558-0.0170.2637No
75DNAJA1DNAJA1
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily A, member 17683-0.0190.2556No
76GNB1GNB1
Entrez,  Source
guanine nucleotide binding protein (G protein), beta polypeptide 17870-0.0220.2429No
77APLP2APLP2
Entrez,  Source
amyloid beta (A4) precursor-like protein 27920-0.0220.2406No
78CCNG1CCNG1
Entrez,  Source
cyclin G18130-0.0260.2264No
79KITLGKITLG
Entrez,  Source
KIT ligand8254-0.0270.2188No
80BAXBAX
Entrez,  Source
BCL2-associated X protein8544-0.0310.1989No
81BZW1BZW1
Entrez,  Source
basic leucine zipper and W2 domains 18626-0.0330.1948No
82ELNELN
Entrez,  Source
elastin (supravalvular aortic stenosis, Williams-Beuren syndrome)8687-0.0330.1924No
83SCG2SCG2
Entrez,  Source
secretogranin II (chromogranin C)8730-0.0340.1914No
84CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)8731-0.0340.1935No
85C3C3
Entrez,  Source
complement component 38749-0.0340.1943No
86CNN3CNN3
Entrez,  Source
calponin 3, acidic8886-0.0360.1863No
87SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 18926-0.0360.1857No
88CACYBPCACYBP
Entrez,  Source
calcyclin binding protein9476-0.0450.1470No
89ANGPTL2ANGPTL2
Entrez,  Source
angiopoietin-like 29536-0.0460.1454No
90CTSZCTSZ
Entrez,  Source
cathepsin Z9975-0.0530.1156No
91TIMM22TIMM22
Entrez,  Source
translocase of inner mitochondrial membrane 22 homolog (yeast)10027-0.0540.1152No
92RPS14RPS14
Entrez,  Source
ribosomal protein S1410205-0.0570.1053No
93TUBBTUBB
Entrez,  Source
tubulin, beta10340-0.0590.0989No
94C1QBC1QB
Entrez,  Source
complement component 1, q subcomponent, B chain10939-0.0720.0582No
95LYL1LYL1
Entrez,  Source
lymphoblastic leukemia derived sequence 111347-0.0830.0327No
96CTSSCTSS
Entrez,  Source
cathepsin S12022-0.104-0.0118No
97MCM7MCM7
Entrez,  Source
MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)12174-0.110-0.0162No
98LCP1LCP1
Entrez,  Source
lymphocyte cytosolic protein 1 (L-plastin)12229-0.113-0.0133No
99CES3CES3
Entrez,  Source
carboxylesterase 3 (brain)12329-0.117-0.0134No
100CSRP1CSRP1
Entrez,  Source
cysteine and glycine-rich protein 112583-0.134-0.0241No
101CDO1CDO1
Entrez,  Source
cysteine dioxygenase, type I12594-0.134-0.0165No
102IGFBP4IGFBP4
Entrez,  Source
insulin-like growth factor binding protein 412663-0.138-0.0129No
103RBP1RBP1
Entrez,  Source
retinol binding protein 1, cellular12674-0.139-0.0050No
104UGDHUGDH
Entrez,  Source
UDP-glucose dehydrogenase12882-0.162-0.0104No
105ID2ID2
Entrez,  Source
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein13029-0.193-0.0094No
106FMO1FMO1
Entrez,  Source
flavin containing monooxygenase 113185-0.244-0.0058No
107ENPP2ENPP2
Entrez,  Source
ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)13234-0.2810.0082No
Table: GSEA details [plain text format]



Fig 2: IGLESIAS_E2FMINUS_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: IGLESIAS_E2FMINUS_UP: Random ES distribution   
Gene set null distribution of ES for IGLESIAS_E2FMINUS_UP