Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | IRITANI_ADPROX_DN |
| Enrichment Score (ES) | 0.6553881 |
| Normalized Enrichment Score (NES) | 2.0402083 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0035997382 |
| FWER p-Value | 0.106 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 12 | 0.803 | 0.1338 | Yes |
| 2 | PROCR | PROCR Entrez, Source | protein C receptor, endothelial (EPCR) | 26 | 0.669 | 0.2451 | Yes |
| 3 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 61 | 0.555 | 0.3356 | Yes |
| 4 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 76 | 0.477 | 0.4146 | Yes |
| 5 | PRNP | PRNP Entrez, Source | prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) | 171 | 0.348 | 0.4659 | Yes |
| 6 | RGS4 | RGS4 Entrez, Source | regulator of G-protein signalling 4 | 219 | 0.308 | 0.5140 | Yes |
| 7 | LPXN | LPXN Entrez, Source | leupaxin | 317 | 0.240 | 0.5470 | Yes |
| 8 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 358 | 0.227 | 0.5820 | Yes |
| 9 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 561 | 0.171 | 0.5955 | Yes |
| 10 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 710 | 0.149 | 0.6094 | Yes |
| 11 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 812 | 0.139 | 0.6251 | Yes |
| 12 | ARL6IP5 | ARL6IP5 Entrez, Source | ADP-ribosylation-like factor 6 interacting protein 5 | 1126 | 0.113 | 0.6206 | Yes |
| 13 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 1285 | 0.105 | 0.6263 | Yes |
| 14 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 1312 | 0.104 | 0.6417 | Yes |
| 15 | SLC38A6 | SLC38A6 Entrez, Source | solute carrier family 38, member 6 | 1356 | 0.101 | 0.6554 | Yes |
| 16 | LTBP2 | LTBP2 Entrez, Source | latent transforming growth factor beta binding protein 2 | 1980 | 0.074 | 0.6209 | No |
| 17 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 2949 | 0.050 | 0.5565 | No |
| 18 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 3143 | 0.046 | 0.5496 | No |
| 19 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 3304 | 0.042 | 0.5447 | No |
| 20 | SELP | SELP Entrez, Source | selectin P (granule membrane protein 140kDa, antigen CD62) | 3754 | 0.034 | 0.5167 | No |
| 21 | ICAM2 | ICAM2 Entrez, Source | intercellular adhesion molecule 2 | 4541 | 0.022 | 0.4613 | No |
| 22 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 4734 | 0.019 | 0.4501 | No |
| 23 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 4953 | 0.016 | 0.4363 | No |
| 24 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 5075 | 0.014 | 0.4296 | No |
| 25 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 5474 | 0.009 | 0.4012 | No |
| 26 | TCN2 | TCN2 Entrez, Source | transcobalamin II; macrocytic anemia | 5550 | 0.008 | 0.3968 | No |
| 27 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 5649 | 0.006 | 0.3905 | No |
| 28 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 5926 | 0.003 | 0.3702 | No |
| 29 | CAP2 | CAP2 Entrez, Source | CAP, adenylate cyclase-associated protein, 2 (yeast) | 6076 | 0.001 | 0.3592 | No |
| 30 | SRPX | SRPX Entrez, Source | sushi-repeat-containing protein, X-linked | 6552 | -0.005 | 0.3244 | No |
| 31 | MAPKAPK3 | MAPKAPK3 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 3 | 7267 | -0.014 | 0.2730 | No |
| 32 | TFEC | TFEC Entrez, Source | transcription factor EC | 7275 | -0.014 | 0.2748 | No |
| 33 | MLLT11 | MLLT11 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 9394 | -0.043 | 0.1228 | No |
| 34 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 9642 | -0.048 | 0.1123 | No |
| 35 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 10146 | -0.056 | 0.0838 | No |
| 36 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 10417 | -0.061 | 0.0737 | No |
| 37 | PLAU | PLAU Entrez, Source | plasminogen activator, urokinase | 10548 | -0.063 | 0.0745 | No |
| 38 | LYL1 | LYL1 Entrez, Source | lymphoblastic leukemia derived sequence 1 | 11347 | -0.083 | 0.0284 | No |
| 39 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 12774 | -0.149 | -0.0538 | No |
| 40 | NRCAM | NRCAM Entrez, Source | neuronal cell adhesion molecule | 13028 | -0.193 | -0.0405 | No |
| 41 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 13292 | -0.382 | 0.0038 | No |
