Details for gene set IRITANI_ADPROX

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in class	double_gel_8d
GeneSet	IRITANI_ADPROX_VASC
Enrichment Score (ES)	0.5893472
Normalized Enrichment Score (NES)	2.1605918
Nominal p-value	0.0
FDR q-value	9.356478E-4
FWER p-Value	0.01

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	COL1A2	COL1A2 Entrez, Source	collagen, type I, alpha 2	3	1.046	0.0752	Yes
2	CLDN7	CLDN7 Entrez, Source	claudin 7	7	0.940	0.1427	Yes
3	SERPINE1	SERPINE1 Entrez, Source	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	12	0.803	0.2003	Yes
4	LAMC2	LAMC2 Entrez, Source	laminin, gamma 2	14	0.770	0.2557	Yes
5	PROCR	PROCR Entrez, Source	protein C receptor, endothelial (EPCR)	26	0.669	0.3031	Yes
6	LDHB	LDHB Entrez, Source	lactate dehydrogenase B	61	0.555	0.3406	Yes
7	CCL2	CCL2 Entrez, Source	chemokine (C-C motif) ligand 2	76	0.477	0.3739	Yes
8	BGN	BGN Entrez, Source	biglycan	143	0.369	0.3955	Yes
9	PRNP	PRNP Entrez, Source	prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)	171	0.348	0.4186	Yes
10	RGS4	RGS4 Entrez, Source	regulator of G-protein signalling 4	219	0.308	0.4372	Yes
11	TAGLN	TAGLN Entrez, Source	transgelin	253	0.280	0.4549	Yes
12	LPXN	LPXN Entrez, Source	leupaxin	317	0.240	0.4675	Yes
13	BTG2	BTG2 Entrez, Source	BTG family, member 2	326	0.238	0.4840	Yes
14	JUN	JUN Entrez, Source	jun oncogene	458	0.194	0.4881	Yes
15	VEGFC	VEGFC Entrez, Source	vascular endothelial growth factor C	496	0.183	0.4984	Yes
16	IGF2BP3	IGF2BP3 Entrez, Source	insulin-like growth factor 2 mRNA binding protein 3	561	0.171	0.5059	Yes
17	IER3	IER3 Entrez, Source	immediate early response 3	598	0.165	0.5151	Yes
18	FLT1	FLT1 Entrez, Source	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	699	0.150	0.5184	Yes
19	CD59	CD59 Entrez, Source	CD59 molecule, complement regulatory protein	710	0.149	0.5284	Yes
20	RHOB	RHOB Entrez, Source	ras homolog gene family, member B	785	0.141	0.5330	Yes
21	NR2F2	NR2F2 Entrez, Source	nuclear receptor subfamily 2, group F, member 2	806	0.139	0.5415	Yes
22	PLA2G4A	PLA2G4A Entrez, Source	phospholipase A2, group IVA (cytosolic, calcium-dependent)	812	0.139	0.5511	Yes
23	EIF2B2	EIF2B2 Entrez, Source	eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa	924	0.127	0.5519	Yes
24	RGS10	RGS10 Entrez, Source	regulator of G-protein signalling 10	1009	0.121	0.5542	Yes
25	BASP1	BASP1 Entrez, Source	brain abundant, membrane attached signal protein 1	1050	0.118	0.5597	Yes
26	ANXA3	ANXA3 Entrez, Source	annexin A3	1062	0.117	0.5673	Yes
27	ARL6IP5	ARL6IP5 Entrez, Source	ADP-ribosylation-like factor 6 interacting protein 5	1126	0.113	0.5707	Yes
28	PRG1	PRG1 Entrez, Source	proteoglycan 1, secretory granule	1285	0.105	0.5663	Yes
29	MMP14	MMP14 Entrez, Source	matrix metallopeptidase 14 (membrane-inserted)	1312	0.104	0.5718	Yes
30	SLC38A6	SLC38A6 Entrez, Source	solute carrier family 38, member 6	1356	0.101	0.5758	Yes
31	ACTA2	ACTA2 Entrez, Source	actin, alpha 2, smooth muscle, aorta	1439	0.096	0.5766	Yes
32	LAMP2	LAMP2 Entrez, Source	lysosomal-associated membrane protein 2	1467	0.095	0.5814	Yes
33	CAPG	CAPG Entrez, Source	capping protein (actin filament), gelsolin-like	1510	0.093	0.5850	Yes
34	CXCL1	CXCL1 Entrez, Source	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	1541	0.092	0.5893	Yes
35	LTBP2	LTBP2 Entrez, Source	latent transforming growth factor beta binding protein 2	1980	0.074	0.5616	No
36	ECE1	ECE1 Entrez, Source	endothelin converting enzyme 1	2048	0.071	0.5617	No
37	TACSTD2	TACSTD2 Entrez, Source	tumor-associated calcium signal transducer 2	2200	0.067	0.5551	No
38	CXCR4	CXCR4 Entrez, Source	chemokine (C-X-C motif) receptor 4	2597	0.058	0.5294	No
39	SLC1A1	SLC1A1 Entrez, Source	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	2638	0.057	0.5304	No
40	PKIA	PKIA Entrez, Source	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	2727	0.054	0.5277	No
41	ANXA6	ANXA6 Entrez, Source	annexin A6	2949	0.050	0.5146	No
42	CD44	CD44 Entrez, Source	CD44 molecule (Indian blood group)	3143	0.046	0.5033	No
43	LPHN2	LPHN2 Entrez, Source	latrophilin 2	3268	0.043	0.4970	No
44	CLU	CLU Entrez, Source	clusterin	3299	0.043	0.4978	No
45	UPP1	UPP1 Entrez, Source	uridine phosphorylase 1	3489	0.039	0.4864	No
46	ITGB5	ITGB5 Entrez, Source	integrin, beta 5	3714	0.035	0.4720	No
47	SELP	SELP Entrez, Source	selectin P (granule membrane protein 140kDa, antigen CD62)	3754	0.034	0.4715	No
48	ICAM2	ICAM2 Entrez, Source	intercellular adhesion molecule 2	4541	0.022	0.4137	No
49	PFKM	PFKM Entrez, Source	phosphofructokinase, muscle	4734	0.019	0.4006	No
50	ATP1B1	ATP1B1 Entrez, Source	ATPase, Na+/K+ transporting, beta 1 polypeptide	4788	0.018	0.3979	No
51	NMT2	NMT2 Entrez, Source	N-myristoyltransferase 2	4917	0.016	0.3894	No
52	IL6	IL6 Entrez, Source	interleukin 6 (interferon, beta 2)	4953	0.016	0.3879	No
53	ARHGDIB	ARHGDIB Entrez, Source	Rho GDP dissociation inhibitor (GDI) beta	5075	0.014	0.3798	No
54	MT3	MT3 Entrez, Source	metallothionein 3 (growth inhibitory factor (neurotrophic))	5102	0.014	0.3789	No
55	BMP6	BMP6 Entrez, Source	bone morphogenetic protein 6	5474	0.009	0.3515	No
56	TCN2	TCN2 Entrez, Source	transcobalamin II; macrocytic anemia	5550	0.008	0.3464	No
57	AXL	AXL Entrez, Source	AXL receptor tyrosine kinase	5649	0.006	0.3394	No
58	PFN2	PFN2 Entrez, Source	profilin 2	5738	0.005	0.3331	No
59	GADD45A	GADD45A Entrez, Source	growth arrest and DNA-damage-inducible, alpha	5788	0.005	0.3298	No
60	TPM1	TPM1 Entrez, Source	tropomyosin 1 (alpha)	5926	0.003	0.3197	No
61	NISCH	NISCH Entrez, Source	nischarin	6031	0.002	0.3119	No
62	CAP2	CAP2 Entrez, Source	CAP, adenylate cyclase-associated protein, 2 (yeast)	6076	0.001	0.3087	No
63	ENO2	ENO2 Entrez, Source	enolase 2 (gamma, neuronal)	6221	-0.001	0.2979	No
64	TGFBI	TGFBI Entrez, Source	transforming growth factor, beta-induced, 68kDa	6410	-0.003	0.2839	No
65	SRPX	SRPX Entrez, Source	sushi-repeat-containing protein, X-linked	6552	-0.005	0.2736	No
66	ALDH2	ALDH2 Entrez, Source	aldehyde dehydrogenase 2 family (mitochondrial)	6734	-0.007	0.2605	No
67	MT1A	MT1A Entrez, Source	metallothionein 1A (functional)	6871	-0.009	0.2509	No
68	LAMA5	LAMA5 Entrez, Source	laminin, alpha 5	7254	-0.014	0.2230	No
69	MAPKAPK3	MAPKAPK3 Entrez, Source	mitogen-activated protein kinase-activated protein kinase 3	7267	-0.014	0.2231	No
70	TFEC	TFEC Entrez, Source	transcription factor EC	7275	-0.014	0.2236	No
71	CDKN1A	CDKN1A Entrez, Source	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	7976	-0.023	0.1724	No
72	TXNRD2	TXNRD2 Entrez, Source	thioredoxin reductase 2	8114	-0.025	0.1639	No
73	SMAD3	SMAD3 Entrez, Source	SMAD, mothers against DPP homolog 3 (Drosophila)	8872	-0.036	0.1093	No
74	ANPEP	ANPEP Entrez, Source	alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150)	8993	-0.037	0.1029	No
75	IL4R	IL4R Entrez, Source	interleukin 4 receptor	9332	-0.042	0.0804	No
76	PGF	PGF Entrez, Source	placental growth factor, vascular endothelial growth factor-related protein	9350	-0.043	0.0822	No
77	MLLT11	MLLT11 Entrez, Source	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	9394	-0.043	0.0821	No
78	UCHL1	UCHL1 Entrez, Source	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	9466	-0.044	0.0799	No
79	CHST1	CHST1 Entrez, Source	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1	9600	-0.047	0.0733	No
80	CDH2	CDH2 Entrez, Source	cadherin 2, type 1, N-cadherin (neuronal)	9642	-0.048	0.0736	No
81	TGM2	TGM2 Entrez, Source	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	9694	-0.049	0.0733	No
82	FHL2	FHL2 Entrez, Source	four and a half LIM domains 2	9790	-0.050	0.0697	No
83	PDLIM4	PDLIM4 Entrez, Source	PDZ and LIM domain 4	10146	-0.056	0.0469	No
84	CSPG2	CSPG2 Entrez, Source	chondroitin sulfate proteoglycan 2 (versican)	10417	-0.061	0.0309	No
85	PLAU	PLAU Entrez, Source	plasminogen activator, urokinase	10548	-0.063	0.0256	No
86	MVP	MVP Entrez, Source	major vault protein	10938	-0.072	0.0014	No
87	LYL1	LYL1 Entrez, Source	lymphoblastic leukemia derived sequence 1	11347	-0.083	-0.0234	No
88	CTSC	CTSC Entrez, Source	cathepsin C	11373	-0.083	-0.0193	No
89	SLC6A8	SLC6A8 Entrez, Source	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	11625	-0.090	-0.0318	No
90	RAC2	RAC2 Entrez, Source	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	11635	-0.090	-0.0260	No
91	SORD	SORD Entrez, Source	sorbitol dehydrogenase	11977	-0.102	-0.0444	No
92	EFEMP1	EFEMP1 Entrez, Source	EGF-containing fibulin-like extracellular matrix protein 1	12182	-0.111	-0.0518	No
93	AGRIN	AGRIN Entrez, Source	agrin	12183	-0.111	-0.0439	No
94	SELE	SELE Entrez, Source	selectin E (endothelial adhesion molecule 1)	12624	-0.136	-0.0673	No
95	FAP	FAP Entrez, Source	fibroblast activation protein, alpha	12774	-0.149	-0.0678	No
96	ICAM1	ICAM1 Entrez, Source	intercellular adhesion molecule 1 (CD54), human rhinovirus receptor	12996	-0.183	-0.0713	No
97	SLC3A2	SLC3A2 Entrez, Source	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	13019	-0.189	-0.0593	No
98	NRCAM	NRCAM Entrez, Source	neuronal cell adhesion molecule	13028	-0.193	-0.0460	No
99	GBP2	GBP2 Entrez, Source	guanylate binding protein 2, interferon-inducible	13292	-0.382	-0.0384	No
100	SLC7A7	SLC7A7 Entrez, Source	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7	13328	-0.584	0.0011	No