Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | LEE_ACOX1_DN |
| Enrichment Score (ES) | -0.4680102 |
| Normalized Enrichment Score (NES) | -1.5836029 |
| Nominal p-value | 0.009478673 |
| FDR q-value | 0.2160963 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 60 | 0.555 | 0.0745 | No |
| 2 | LIPC | LIPC Entrez, Source | lipase, hepatic | 92 | 0.451 | 0.1362 | No |
| 3 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 258 | 0.276 | 0.1632 | No |
| 4 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 439 | 0.198 | 0.1778 | No |
| 5 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 581 | 0.167 | 0.1910 | No |
| 6 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 610 | 0.163 | 0.2122 | No |
| 7 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 772 | 0.143 | 0.2204 | No |
| 8 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 1492 | 0.094 | 0.1797 | No |
| 9 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 1522 | 0.093 | 0.1908 | No |
| 10 | PAH | PAH Entrez, Source | phenylalanine hydroxylase | 1638 | 0.087 | 0.1946 | No |
| 11 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 2620 | 0.057 | 0.1289 | No |
| 12 | MYH1 | MYH1 Entrez, Source | myosin, heavy chain 1, skeletal muscle, adult | 3074 | 0.047 | 0.1016 | No |
| 13 | ATP2A1 | ATP2A1 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 4573 | 0.021 | -0.0080 | No |
| 14 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 4766 | 0.019 | -0.0198 | No |
| 15 | MASP1 | MASP1 Entrez, Source | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 5174 | 0.013 | -0.0486 | No |
| 16 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 5783 | 0.005 | -0.0936 | No |
| 17 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 6249 | -0.001 | -0.1284 | No |
| 18 | SERPINA1 | SERPINA1 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 6827 | -0.008 | -0.1706 | No |
| 19 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 8552 | -0.031 | -0.2958 | No |
| 20 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 8712 | -0.034 | -0.3029 | No |
| 21 | GSTA3 | GSTA3 Entrez, Source | glutathione S-transferase A3 | 9247 | -0.041 | -0.3373 | No |
| 22 | RNASE4 | RNASE4 Entrez, Source | ribonuclease, RNase A family, 4 | 9382 | -0.043 | -0.3412 | No |
| 23 | PRODH | PRODH Entrez, Source | proline dehydrogenase (oxidase) 1 | 9764 | -0.050 | -0.3628 | No |
| 24 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 10366 | -0.060 | -0.3996 | No |
| 25 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 10401 | -0.060 | -0.3936 | No |
| 26 | SFTPD | SFTPD Entrez, Source | surfactant, pulmonary-associated protein D | 10726 | -0.067 | -0.4084 | No |
| 27 | DPP4 | DPP4 Entrez, Source | dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) | 10965 | -0.073 | -0.4160 | No |
| 28 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 11140 | -0.077 | -0.4182 | No |
| 29 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 11235 | -0.079 | -0.4140 | No |
| 30 | CPOX | CPOX Entrez, Source | coproporphyrinogen oxidase | 11247 | -0.080 | -0.4034 | No |
| 31 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 11286 | -0.081 | -0.3948 | No |
| 32 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 11607 | -0.089 | -0.4062 | No |
| 33 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 11732 | -0.093 | -0.4022 | No |
| 34 | NINJ1 | NINJ1 Entrez, Source | ninjurin 1 | 12581 | -0.133 | -0.4470 | Yes |
| 35 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 12861 | -0.160 | -0.4452 | Yes |
| 36 | AKAP11 | AKAP11 Entrez, Source | A kinase (PRKA) anchor protein 11 | 12961 | -0.175 | -0.4278 | Yes |
| 37 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 12994 | -0.182 | -0.4043 | Yes |
| 38 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 13027 | -0.192 | -0.3793 | Yes |
| 39 | CYP26A1 | CYP26A1 Entrez, Source | cytochrome P450, family 26, subfamily A, polypeptide 1 | 13188 | -0.246 | -0.3563 | Yes |
| 40 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 13189 | -0.247 | -0.3213 | Yes |
| 41 | SLCO2B1 | SLCO2B1 Entrez, Source | solute carrier organic anion transporter family, member 2B1 | 13208 | -0.258 | -0.2859 | Yes |
| 42 | KHK | KHK Entrez, Source | ketohexokinase (fructokinase) | 13261 | -0.313 | -0.2453 | Yes |
| 43 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13289 | -0.373 | -0.1943 | Yes |
| 44 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 13293 | -0.383 | -0.1400 | Yes |
| 45 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13314 | -0.464 | -0.0756 | Yes |
| 46 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 13326 | -0.545 | 0.0012 | Yes |
