Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LEE_E2F1_UP |
| Enrichment Score (ES) | 0.5775422 |
| Normalized Enrichment Score (NES) | 1.7966993 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.032680802 |
| FWER p-Value | 0.972 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 10 | 0.815 | 0.0937 | Yes |
| 2 | LPL | LPL Entrez, Source | lipoprotein lipase | 24 | 0.680 | 0.1715 | Yes |
| 3 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 28 | 0.668 | 0.2487 | Yes |
| 4 | DEFB1 | DEFB1 Entrez, Source | defensin, beta 1 | 158 | 0.356 | 0.2803 | Yes |
| 5 | GSTM2 | GSTM2 Entrez, Source | glutathione S-transferase M2 (muscle) | 186 | 0.331 | 0.3166 | Yes |
| 6 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 200 | 0.321 | 0.3528 | Yes |
| 7 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 234 | 0.297 | 0.3847 | Yes |
| 8 | TM4SF4 | TM4SF4 Entrez, Source | transmembrane 4 L six family member 4 | 312 | 0.244 | 0.4072 | Yes |
| 9 | ACTG2 | ACTG2 Entrez, Source | actin, gamma 2, smooth muscle, enteric | 391 | 0.212 | 0.4259 | Yes |
| 10 | FMO3 | FMO3 Entrez, Source | flavin containing monooxygenase 3 | 416 | 0.205 | 0.4479 | Yes |
| 11 | IGFBP1 | IGFBP1 Entrez, Source | insulin-like growth factor binding protein 1 | 531 | 0.177 | 0.4598 | Yes |
| 12 | CTSE | CTSE Entrez, Source | cathepsin E | 580 | 0.167 | 0.4756 | Yes |
| 13 | CPE | CPE Entrez, Source | carboxypeptidase E | 589 | 0.167 | 0.4943 | Yes |
| 14 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 638 | 0.159 | 0.5091 | Yes |
| 15 | LEPR | LEPR Entrez, Source | leptin receptor | 711 | 0.149 | 0.5210 | Yes |
| 16 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 738 | 0.146 | 0.5359 | Yes |
| 17 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 785 | 0.141 | 0.5488 | Yes |
| 18 | PALMD | PALMD Entrez, Source | palmdelphin | 958 | 0.125 | 0.5503 | Yes |
| 19 | PLSCR1 | PLSCR1 Entrez, Source | phospholipid scramblase 1 | 1073 | 0.116 | 0.5551 | Yes |
| 20 | GSTM1 | GSTM1 Entrez, Source | glutathione S-transferase M1 | 1149 | 0.112 | 0.5625 | Yes |
| 21 | BCL2A1 | BCL2A1 Entrez, Source | BCL2-related protein A1 | 1231 | 0.108 | 0.5689 | Yes |
| 22 | MFGE8 | MFGE8 Entrez, Source | milk fat globule-EGF factor 8 protein | 1496 | 0.094 | 0.5600 | Yes |
| 23 | NUCB2 | NUCB2 Entrez, Source | nucleobindin 2 | 1503 | 0.094 | 0.5704 | Yes |
| 24 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 1550 | 0.092 | 0.5775 | Yes |
| 25 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 1825 | 0.079 | 0.5661 | No |
| 26 | CXADR | CXADR Entrez, Source | coxsackie virus and adenovirus receptor | 2231 | 0.066 | 0.5434 | No |
| 27 | GPC3 | GPC3 Entrez, Source | glypican 3 | 2514 | 0.059 | 0.5290 | No |
| 28 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 4307 | 0.025 | 0.3972 | No |
| 29 | LCN2 | LCN2 Entrez, Source | lipocalin 2 (oncogene 24p3) | 4934 | 0.016 | 0.3520 | No |
| 30 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 5434 | 0.009 | 0.3155 | No |
| 31 | CD63 | CD63 Entrez, Source | CD63 molecule | 6300 | -0.002 | 0.2507 | No |
| 32 | SPON2 | SPON2 Entrez, Source | spondin 2, extracellular matrix protein | 6569 | -0.005 | 0.2312 | No |
| 33 | CSTB | CSTB Entrez, Source | cystatin B (stefin B) | 7027 | -0.011 | 0.1981 | No |
| 34 | TAGLN2 | TAGLN2 Entrez, Source | transgelin 2 | 7600 | -0.018 | 0.1572 | No |
| 35 | TFF3 | TFF3 Entrez, Source | trefoil factor 3 (intestinal) | 8741 | -0.034 | 0.0754 | No |
| 36 | NT5E | NT5E Entrez, Source | 5'-nucleotidase, ecto (CD73) | 11299 | -0.081 | -0.1075 | No |
| 37 | IFIT2 | IFIT2 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 2 | 11566 | -0.088 | -0.1173 | No |
| 38 | CTSS | CTSS Entrez, Source | cathepsin S | 12022 | -0.104 | -0.1395 | No |
| 39 | SPINK1 | SPINK1 Entrez, Source | serine peptidase inhibitor, Kazal type 1 | 12063 | -0.106 | -0.1303 | No |
| 40 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12441 | -0.123 | -0.1443 | No |
| 41 | IFI44 | IFI44 Entrez, Source | interferon-induced protein 44 | 12681 | -0.140 | -0.1461 | No |
| 42 | USP18 | USP18 Entrez, Source | ubiquitin specific peptidase 18 | 12833 | -0.156 | -0.1393 | No |
| 43 | XDH | XDH Entrez, Source | xanthine dehydrogenase | 13126 | -0.217 | -0.1361 | No |
| 44 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 13279 | -0.344 | -0.1077 | No |
| 45 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 13311 | -0.439 | -0.0591 | No |
| 46 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 13324 | -0.530 | 0.0014 | No |
