Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_8d
GeneSetLEI_MYB_REGULATED_GENES
Enrichment Score (ES)0.55286777
Normalized Enrichment Score (NES)2.205032
Nominal p-value0.0
FDR q-value2.2333532E-4
FWER p-Value0.0020
Table: GSEA Results Summary



Fig 1: Enrichment plot: LEI_MYB_REGULATED_GENES   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 231.0460.0404Yes
2IGFBP7IGFBP7
Entrez,  Source
insulin-like growth factor binding protein 750.9720.0781Yes
3VIMVIM
Entrez,  Source
vimentin60.9530.1151Yes
4CLDN7CLDN7
Entrez,  Source
claudin 770.9400.1517Yes
5ANXA1ANXA1
Entrez,  Source
annexin A1100.8150.1832Yes
6CCND2CCND2
Entrez,  Source
cyclin D2110.8150.2149Yes
7SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1120.8030.2461Yes
8LAMC2LAMC2
Entrez,  Source
laminin, gamma 2140.7700.2759Yes
9CD24CD24
Entrez,  Source
CD24 molecule170.7260.3040Yes
10DAB2DAB2
Entrez,  Source
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)310.6610.3287Yes
11RGS2RGS2
Entrez,  Source
regulator of G-protein signalling 2, 24kDa420.6160.3519Yes
12LDHBLDHB
Entrez,  Source
lactate dehydrogenase B610.5550.3720Yes
13CCL2CCL2
Entrez,  Source
chemokine (C-C motif) ligand 2760.4770.3895Yes
14SERPINE2SERPINE2
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 21040.4240.4039Yes
15TNFAIP6TNFAIP6
Entrez,  Source
tumor necrosis factor, alpha-induced protein 61170.4020.4186Yes
16CRYABCRYAB
Entrez,  Source
crystallin, alpha B1410.3710.4313Yes
17HSPA4HSPA4
Entrez,  Source
heat shock 70kDa protein 41920.3280.4402Yes
18GJA1GJA1
Entrez,  Source
gap junction protein, alpha 1, 43kDa (connexin 43)1960.3240.4526Yes
19SPARCSPARC
Entrez,  Source
secreted protein, acidic, cysteine-rich (osteonectin)2340.2970.4613Yes
20MSNMSN
Entrez,  Source
moesin2480.2850.4714Yes
21PRSS23PRSS23
Entrez,  Source
protease, serine, 232510.2810.4822Yes
22PEA15PEA15
Entrez,  Source
phosphoprotein enriched in astrocytes 152520.2810.4931Yes
23DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 12570.2760.5035Yes
24TSC22D3TSC22D3
Entrez,  Source
TSC22 domain family, member 32760.2630.5124Yes
25IFITM2IFITM2
Entrez,  Source
interferon induced transmembrane protein 2 (1-8D)2810.2600.5222Yes
26TIMP3TIMP3
Entrez,  Source
TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory)4060.2080.5208Yes
27PLK2PLK2
Entrez,  Source
polo-like kinase 2 (Drosophila)4140.2060.5283Yes
28PORPOR
Entrez,  Source
P450 (cytochrome) oxidoreductase4210.2040.5358Yes
29TACSTD1TACSTD1
Entrez,  Source
tumor-associated calcium signal transducer 14220.2040.5437Yes
30CLDN3CLDN3
Entrez,  Source
claudin 35040.1810.5446Yes
31SLC20A1SLC20A1
Entrez,  Source
solute carrier family 20 (phosphate transporter), member 15430.1730.5484Yes
32BAIAP2BAIAP2
Entrez,  Source
BAI1-associated protein 25720.1690.5529Yes
33CD59CD59
Entrez,  Source
CD59 molecule, complement regulatory protein7100.1490.5483No
34EMP2EMP2
Entrez,  Source
epithelial membrane protein 28740.1320.5410No
35PTTG1IPPTTG1IP
Entrez,  Source
pituitary tumor-transforming 1 interacting protein8810.1310.5456No
36IL1BIL1B
Entrez,  Source
interleukin 1, beta10140.1210.5402No
37BASP1BASP1
Entrez,  Source
brain abundant, membrane attached signal protein 110500.1180.5422No
38ANXA3ANXA3
Entrez,  Source
annexin A310620.1170.5458No
39HSPB1HSPB1
Entrez,  Source
heat shock 27kDa protein 110840.1160.5487No
40SLC16A3SLC16A3
Entrez,  Source
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)11100.1140.5513No
41ZFP36L2ZFP36L2
Entrez,  Source
zinc finger protein 36, C3H type-like 212060.1090.5483No
42PRG1PRG1
Entrez,  Source
proteoglycan 1, secretory granule12850.1050.5464No
43DAXXDAXX
Entrez,  Source
death-associated protein 613380.1020.5464No
44SFRP1SFRP1
Entrez,  Source
secreted frizzled-related protein 113670.1000.5482No
45ACTA2ACTA2
Entrez,  Source
actin, alpha 2, smooth muscle, aorta14390.0960.5466No
46S100A10S100A10
Entrez,  Source
S100 calcium binding protein A1014440.0960.5500No
47SELENBP1SELENBP1
Entrez,  Source
selenium binding protein 114920.0940.5501No
48SERPINB5SERPINB5
Entrez,  Source
serpin peptidase inhibitor, clade B (ovalbumin), member 516610.0860.5406No
49PTTG1PTTG1
Entrez,  Source
pituitary tumor-transforming 117340.0830.5384No
50CEBPBCEBPB
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), beta17740.0820.5386No
51KLF9KLF9
Entrez,  Source
Kruppel-like factor 917810.0810.5413No
52ATP2A3ATP2A3
Entrez,  Source
ATPase, Ca++ transporting, ubiquitous18000.0800.5430No
53FGFBP1FGFBP1
Entrez,  Source
fibroblast growth factor binding protein 120720.0710.5252No
54BTG1BTG1
Entrez,  Source
B-cell translocation gene 1, anti-proliferative23500.0630.5066No
55DPM2DPM2
Entrez,  Source
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit24110.0620.5044No
56ACTR2ACTR2
Entrez,  Source
ARP2 actin-related protein 2 homolog (yeast)24840.0600.5013No
57CRABP2CRABP2
Entrez,  Source
cellular retinoic acid binding protein 225660.0580.4974No
58FN1FN1
Entrez,  Source
fibronectin 126370.0570.4942No
59CTSDCTSD
Entrez,  Source
cathepsin D (lysosomal aspartyl peptidase)27940.0530.4844No
60CDC25BCDC25B
Entrez,  Source
cell division cycle 25B30660.0470.4656No
61UBCUBC
Entrez,  Source
ubiquitin C31360.0460.4622No
62GRIP2GRIP2
Entrez,  Source
glutamate receptor interacting protein 231500.0450.4629No
63CLUCLU
Entrez,  Source
clusterin32990.0430.4533No
64PFKLPFKL
Entrez,  Source
phosphofructokinase, liver33250.0420.4530No
65MAP1LC3BMAP1LC3B
Entrez,  Source
microtubule-associated protein 1 light chain 3 beta34060.0400.4485No
66BICD2BICD2
Entrez,  Source
bicaudal D homolog 2 (Drosophila)34200.0400.4491No
67MRPL49MRPL49
Entrez,  Source
mitochondrial ribosomal protein L4934630.0390.4474No
68TRIOTRIO
Entrez,  Source
triple functional domain (PTPRF interacting)34910.0390.4469No
69KIAA0101KIAA0101
Entrez,  Source
KIAA010135930.0370.4406No
70LITAFLITAF
Entrez,  Source
lipopolysaccharide-induced TNF factor36540.0360.4375No
71SERPINB3SERPINB3
Entrez,  Source
serpin peptidase inhibitor, clade B (ovalbumin), member 337240.0350.4336No
72CDH1CDH1
Entrez,  Source
cadherin 1, type 1, E-cadherin (epithelial)37390.0350.4338No
73LTA4HLTA4H
Entrez,  Source
leukotriene A4 hydrolase37670.0340.4331No
74ELOVL5ELOVL5
Entrez,  Source
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)37870.0340.4330No
75MAOAMAOA
Entrez,  Source
monoamine oxidase A38330.0330.4308No
76PCCBPCCB
Entrez,  Source
propionyl Coenzyme A carboxylase, beta polypeptide38730.0320.4291No
77GRNGRN
Entrez,  Source
granulin39020.0320.4282No
78ASAH1ASAH1
Entrez,  Source
N-acylsphingosine amidohydrolase (acid ceramidase) 139040.0320.4294No
79TFF1TFF1
Entrez,  Source
trefoil factor 1 (breast cancer, estrogen-inducible sequence expressed in)39180.0320.4296No
80CTCFCTCF
Entrez,  Source
CCCTC-binding factor (zinc finger protein)39670.0310.4272No
81TMEM158TMEM158
Entrez,  Source
transmembrane protein 15840320.0300.4234No
82TUBG1TUBG1
Entrez,  Source
tubulin, gamma 142120.0270.4109No
83S100A8S100A8
Entrez,  Source
S100 calcium binding protein A842600.0260.4083No
84MCL1MCL1
Entrez,  Source
myeloid cell leukemia sequence 1 (BCL2-related)43070.0250.4058No
85ITPR3ITPR3
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 343440.0250.4040No
86SERPING1SERPING1
Entrez,  Source
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)45470.0220.3895No
87PTHLHPTHLH
Entrez,  Source
parathyroid hormone-like hormone45940.0210.3868No
88GOSR1GOSR1
Entrez,  Source
golgi SNAP receptor complex member 146740.0200.3816No
89LUMLUM
Entrez,  Source
lumican47280.0190.3783No
90CFLARCFLAR
Entrez,  Source
CASP8 and FADD-like apoptosis regulator48630.0170.3688No
91LCN2LCN2
Entrez,  Source
lipocalin 2 (oncogene 24p3)49340.0160.3641No
92IL6IL6
Entrez,  Source
interleukin 6 (interferon, beta 2)49530.0160.3633No
93ACBD3ACBD3
Entrez,  Source
acyl-Coenzyme A binding domain containing 349640.0160.3632No
94HSPD1HSPD1
Entrez,  Source
heat shock 60kDa protein 1 (chaperonin)51530.0130.3494No
95CTSKCTSK
Entrez,  Source
cathepsin K (pycnodysostosis)54160.0100.3298No
96AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase56490.0060.3124No
97PPIBPPIB
Entrez,  Source
peptidylprolyl isomerase B (cyclophilin B)57130.0060.3078No
98SLC9A3R1SLC9A3R1
Entrez,  Source
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 157920.0050.3021No
99BRD2BRD2
Entrez,  Source
bromodomain containing 258760.0040.2959No
100TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)59260.0030.2923No
101PCNAPCNA
Entrez,  Source
proliferating cell nuclear antigen59380.0030.2916No
102LAMA3LAMA3
Entrez,  Source
laminin, alpha 36404-0.0030.2563No
103TGFBITGFBI
Entrez,  Source
transforming growth factor, beta-induced, 68kDa6410-0.0030.2560No
104APEX1APEX1
Entrez,  Source
APEX nuclease (multifunctional DNA repair enzyme) 16464-0.0040.2522No
105LASP1LASP1
Entrez,  Source
LIM and SH3 protein 16500-0.0040.2497No
106PSMA4PSMA4
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 46523-0.0050.2482No
107GPIGPI
Entrez,  Source
glucose phosphate isomerase6561-0.0050.2456No
108EEF1A2EEF1A2
Entrez,  Source
eukaryotic translation elongation factor 1 alpha 26587-0.0060.2439No
109PTGDSPTGDS
Entrez,  Source
prostaglandin D2 synthase 21kDa (brain)6790-0.0080.2288No
110MT1AMT1A
Entrez,  Source
metallothionein 1A (functional)6871-0.0090.2231No
111ALAS1ALAS1
Entrez,  Source
aminolevulinate, delta-, synthase 16928-0.0100.2192No
112SMARCA2SMARCA2
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 26971-0.0100.2164No
113ATP5DATP5D
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit7018-0.0110.2133No
114FASTKFASTK
Entrez,  Source
Fas-activated serine/threonine kinase7022-0.0110.2135No
115ME1ME1
Entrez,  Source
malic enzyme 1, NADP(+)-dependent, cytosolic7060-0.0110.2112No
116CLEC11ACLEC11A
Entrez,  Source
C-type lectin domain family 11, member A7198-0.0130.2012No
117FLOT1FLOT1
Entrez,  Source
flotillin 17222-0.0130.2000No
118LAMA5LAMA5
Entrez,  Source
laminin, alpha 57254-0.0140.1982No
119EPOREPOR
Entrez,  Source
erythropoietin receptor7361-0.0150.1907No
120FBP1FBP1
Entrez,  Source
fructose-1,6-bisphosphatase 17433-0.0160.1859No
121CREB3L2CREB3L2
Entrez,  Source
cAMP responsive element binding protein 3-like 27447-0.0160.1856No
122HSPE1HSPE1
Entrez,  Source
heat shock 10kDa protein 1 (chaperonin 10)7672-0.0190.1693No
123DNAJA1DNAJA1
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily A, member 17683-0.0190.1692No
124MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)7715-0.0200.1676No
125GATA3GATA3
Entrez,  Source
GATA binding protein 37809-0.0210.1614No
126BHLHB2BHLHB2
Entrez,  Source
basic helix-loop-helix domain containing, class B, 27852-0.0210.1590No
127CDKN1ACDKN1A
Entrez,  Source
cyclin-dependent kinase inhibitor 1A (p21, Cip1)7976-0.0230.1505No
128SLC25A1SLC25A1
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 18088-0.0250.1431No
129FADS1FADS1
Entrez,  Source
fatty acid desaturase 18129-0.0250.1410No
130SERPINB2SERPINB2
Entrez,  Source
serpin peptidase inhibitor, clade B (ovalbumin), member 28340-0.0280.1261No
131SIAHBP1SIAHBP1
Entrez,  Source
-8490-0.0310.1160No
132CCND1CCND1
Entrez,  Source
cyclin D18524-0.0310.1147No
133TFF3TFF3
Entrez,  Source
trefoil factor 3 (intestinal)8741-0.0340.0996No
134SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)8872-0.0360.0911No
135SERBP1SERBP1
Entrez,  Source
SERPINE1 mRNA binding protein 18948-0.0370.0868No
136NDUFV1NDUFV1
Entrez,  Source
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa9093-0.0390.0774No
137EFNA3EFNA3
Entrez,  Source
ephrin-A39124-0.0390.0766No
138SH2B3SH2B3
Entrez,  Source
SH2B adaptor protein 39274-0.0410.0669No
139RRADRRAD
Entrez,  Source
Ras-related associated with diabetes9408-0.0440.0584No
140TMEM106CTMEM106C
Entrez,  Source
transmembrane protein 106C9570-0.0460.0480No
141RASA1RASA1
Entrez,  Source
RAS p21 protein activator (GTPase activating protein) 19586-0.0470.0487No
142ARF6ARF6
Entrez,  Source
ADP-ribosylation factor 69627-0.0470.0475No
143TARDBPTARDBP
Entrez,  Source
TAR DNA binding protein9687-0.0480.0448No
144TGM2TGM2
Entrez,  Source
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)9694-0.0490.0463No
145FHL2FHL2
Entrez,  Source
four and a half LIM domains 29790-0.0500.0410No
146GNG11GNG11
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma 119846-0.0510.0388No
147SLC2A3SLC2A3
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 39985-0.0530.0304No
148RPS15ARPS15A
Entrez,  Source
ribosomal protein S15a10118-0.0550.0225No
149IL1RNIL1RN
Entrez,  Source
interleukin 1 receptor antagonist10196-0.0570.0188No
150XRCC5XRCC5
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)10199-0.0570.0209No
151JUPJUP
Entrez,  Source
junction plakoglobin10241-0.0570.0200No
152STIP1STIP1
Entrez,  Source
stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein)10313-0.0590.0169No
153TUBBTUBB
Entrez,  Source
tubulin, beta10340-0.0590.0172No
154NXF1NXF1
Entrez,  Source
nuclear RNA export factor 110534-0.0630.0049No
155PPIDPPID
Entrez,  Source
peptidylprolyl isomerase D (cyclophilin D)10675-0.066-0.0032No
156ATP6V0D1ATP6V0D1
Entrez,  Source
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d110697-0.066-0.0022No
157S100A9S100A9
Entrez,  Source
S100 calcium binding protein A910706-0.066-0.0002No
158EXOSC7EXOSC7
Entrez,  Source
exosome component 710861-0.070-0.0092No
159TXNRD1TXNRD1
Entrez,  Source
thioredoxin reductase 110870-0.070-0.0071No
160SLC7A5SLC7A5
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 510889-0.071-0.0057No
161EIF3S9EIF3S9
Entrez,  Source
eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa10891-0.071-0.0031No
162LGALS3BPLGALS3BP
Entrez,  Source
lectin, galactoside-binding, soluble, 3 binding protein10919-0.071-0.0024No
163MDKMDK
Entrez,  Source
midkine (neurite growth-promoting factor 2)10954-0.072-0.0021No
164AP2A2AP2A2
Entrez,  Source
adaptor-related protein complex 2, alpha 2 subunit10959-0.0720.0004No
165CYP1B1CYP1B1
Entrez,  Source
cytochrome P450, family 1, subfamily B, polypeptide 110964-0.0730.0029No
166ANP32BANP32B
Entrez,  Source
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B11023-0.0740.0013No
167ASNSASNS
Entrez,  Source
asparagine synthetase11024-0.0740.0042No
168EEF1DEEF1D
Entrez,  Source
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)11131-0.077-0.0009No
169CDK4CDK4
Entrez,  Source
cyclin-dependent kinase 411432-0.085-0.0204No
170RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 111564-0.088-0.0270No
171TM7SF2TM7SF2
Entrez,  Source
transmembrane 7 superfamily member 211819-0.096-0.0426No
172NME1NME1
Entrez,  Source
non-metastatic cells 1, protein (NM23A) expressed in11914-0.100-0.0458No
173EBPEBP
Entrez,  Source
emopamil binding protein (sterol isomerase)11949-0.101-0.0445No
174AURKBAURKB
Entrez,  Source
aurora kinase B11998-0.103-0.0442No
175SPINK1SPINK1
Entrez,  Source
serine peptidase inhibitor, Kazal type 112063-0.106-0.0449No
176ISG20ISG20
Entrez,  Source
interferon stimulated exonuclease gene 20kDa12100-0.107-0.0435No
177IDI1IDI1
Entrez,  Source
isopentenyl-diphosphate delta isomerase 112159-0.110-0.0437No
178MCM7MCM7
Entrez,  Source
MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)12174-0.110-0.0404No
179BLCAPBLCAP
Entrez,  Source
bladder cancer associated protein12271-0.115-0.0433No
180GPR56GPR56
Entrez,  Source
G protein-coupled receptor 5612282-0.115-0.0396No
181PLEC1PLEC1
Entrez,  Source
plectin 1, intermediate filament binding protein 500kDa12297-0.116-0.0361No
182LY6G6CLY6G6C
Entrez,  Source
lymphocyte antigen 6 complex, locus G6C12312-0.117-0.0327No
183MAGED2MAGED2
Entrez,  Source
melanoma antigen family D, 212317-0.117-0.0284No
184HMOX1HMOX1
Entrez,  Source
heme oxygenase (decycling) 112319-0.117-0.0239No
185GSTO1GSTO1
Entrez,  Source
glutathione S-transferase omega 112328-0.117-0.0200No
186FEN1FEN1
Entrez,  Source
flap structure-specific endonuclease 112418-0.122-0.0220No
187NRD1NRD1
Entrez,  Source
nardilysin (N-arginine dibasic convertase)12495-0.127-0.0229No
188MUC1MUC1
Entrez,  Source
mucin 1, cell surface associated12515-0.129-0.0193No
189AURKAAURKA
Entrez,  Source
aurora kinase A12546-0.131-0.0164No
190NINJ1NINJ1
Entrez,  Source
ninjurin 112581-0.133-0.0138No
191SNRPN /// SNURF12618-0.136-0.0113No
192XBP1XBP1
Entrez,  Source
X-box binding protein 112661-0.138-0.0091No
193XRCC6XRCC6
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa)12731-0.144-0.0088No
194GM2AGM2A
Entrez,  Source
GM2 ganglioside activator12760-0.148-0.0052No
195FAPFAP
Entrez,  Source
fibroblast activation protein, alpha12774-0.149-0.0004No
196DHRS3DHRS3
Entrez,  Source
dehydrogenase/reductase (SDR family) member 312962-0.175-0.0078No
197CLIC4CLIC4
Entrez,  Source
chloride intracellular channel 413070-0.202-0.0081No
198HNRPA1HNRPA1
Entrez,  Source
heterogeneous nuclear ribonucleoprotein A113096-0.208-0.0019No
199FADS2FADS2
Entrez,  Source
fatty acid desaturase 213155-0.2260.0024No
200CRIP2CRIP2
Entrez,  Source
cysteine-rich protein 213251-0.3010.0069No
Table: GSEA details [plain text format]



Fig 2: LEI_MYB_REGULATED_GENES   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: LEI_MYB_REGULATED_GENES: Random ES distribution   
Gene set null distribution of ES for LEI_MYB_REGULATED_GENES