Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_8d
GeneSetLI_FETAL_VS_WT_KIDNEY_UP
Enrichment Score (ES)0.5130945
Normalized Enrichment Score (NES)1.8808174
Nominal p-value0.0
FDR q-value0.018866729
FWER p-Value0.731
Table: GSEA Results Summary



Fig 1: Enrichment plot: LI_FETAL_VS_WT_KIDNEY_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 231.0460.0816Yes
2IGFBP7IGFBP7
Entrez,  Source
insulin-like growth factor binding protein 750.9720.1576Yes
3DAB2DAB2
Entrez,  Source
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)310.6610.2075Yes
4MAFMAF
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)730.4840.2423Yes
5CRYABCRYAB
Entrez,  Source
crystallin, alpha B1410.3710.2663Yes
6AHNAKAHNAK
Entrez,  Source
AHNAK nucleoprotein (desmoyokin)1650.3500.2919Yes
7PRNPPRNP
Entrez,  Source
prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)1710.3480.3188Yes
8SLC22A5SLC22A5
Entrez,  Source
solute carrier family 22 (organic cation transporter), member 52040.3190.3413Yes
9ENPEPENPEP
Entrez,  Source
glutamyl aminopeptidase (aminopeptidase A)3380.2340.3495Yes
10CX3CL1CX3CL1
Entrez,  Source
chemokine (C-X3-C motif) ligand 13750.2180.3638Yes
11CDS1CDS1
Entrez,  Source
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 14090.2070.3776Yes
12HERPUD1HERPUD1
Entrez,  Source
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 14300.2010.3918Yes
13CLDN3CLDN3
Entrez,  Source
claudin 35040.1810.4004Yes
14TPST1TPST1
Entrez,  Source
tyrosylprotein sulfotransferase 15870.1670.4073Yes
15CREBL2CREBL2
Entrez,  Source
cAMP responsive element binding protein-like 25950.1660.4197Yes
16ALCAMALCAM
Entrez,  Source
activated leukocyte cell adhesion molecule6460.1580.4283Yes
17LEPRLEPR
Entrez,  Source
leptin receptor7110.1490.4352Yes
18ANXA4ANXA4
Entrez,  Source
annexin A47220.1480.4460Yes
19IMPA2IMPA2
Entrez,  Source
inositol(myo)-1(or 4)-monophosphatase 27350.1460.4566Yes
20TFPITFPI
Entrez,  Source
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)8250.1370.4605Yes
21TSPOTSPO
Entrez,  Source
translocator protein (18kDa)8360.1360.4704Yes
22DYNC2LI1DYNC2LI1
Entrez,  Source
dynein, cytoplasmic 2, light intermediate chain 18710.1320.4782Yes
23FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)9210.1270.4844Yes
24ANXA3ANXA3
Entrez,  Source
annexin A310620.1170.4830Yes
25SPP1SPP1
Entrez,  Source
secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)11050.1140.4888Yes
26PLCG2PLCG2
Entrez,  Source
phospholipase C, gamma 2 (phosphatidylinositol-specific)11160.1140.4969Yes
27SCP2SCP2
Entrez,  Source
sterol carrier protein 211700.1110.5016Yes
28ALDH1A1ALDH1A1
Entrez,  Source
aldehyde dehydrogenase 1 family, member A111830.1100.5093Yes
29CASTCAST
Entrez,  Source
calpastatin12580.1070.5120Yes
30S100A10S100A10
Entrez,  Source
S100 calcium binding protein A1014440.0960.5056Yes
31LAMP2LAMP2
Entrez,  Source
lysosomal-associated membrane protein 214670.0950.5114Yes
32TGOLN2TGOLN2
Entrez,  Source
trans-golgi network protein 217180.0840.4991Yes
33DUSP9DUSP9
Entrez,  Source
dual specificity phosphatase 917230.0840.5053Yes
34KIFC3KIFC3
Entrez,  Source
kinesin family member C317240.0840.5119Yes
35SERINC5SERINC5
Entrez,  Source
serine incorporator 518580.0780.5079Yes
36TRIM2TRIM2
Entrez,  Source
tripartite motif-containing 218710.0780.5131Yes
37TMED5TMED5
Entrez,  Source
transmembrane emp24 protein transport domain containing 520900.0700.5021No
38CAV2CAV2
Entrez,  Source
caveolin 221510.0690.5029No
39TACSTD2TACSTD2
Entrez,  Source
tumor-associated calcium signal transducer 222000.0670.5046No
40PEX7PEX7
Entrez,  Source
peroxisomal biogenesis factor 723000.0640.5021No
41APOEAPOE
Entrez,  Source
apolipoprotein E23450.0630.5038No
42GNAI1GNAI1
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 124240.0610.5027No
43CYB5ACYB5A
Entrez,  Source
cytochrome b5 type A (microsomal)25950.0580.4943No
44SMPDL3ASMPDL3A
Entrez,  Source
sphingomyelin phosphodiesterase, acid-like 3A26870.0550.4918No
45GUCY1A3GUCY1A3
Entrez,  Source
guanylate cyclase 1, soluble, alpha 331070.0460.4638No
46ACSL1ACSL1
Entrez,  Source
acyl-CoA synthetase long-chain family member 132160.0440.4591No
47CLUCLU
Entrez,  Source
clusterin32990.0430.4562No
48PMP22PMP22
Entrez,  Source
peripheral myelin protein 2234640.0390.4469No
49SYNGR2SYNGR2
Entrez,  Source
synaptogyrin 236120.0370.4386No
50CDH1CDH1
Entrez,  Source
cadherin 1, type 1, E-cadherin (epithelial)37390.0350.4318No
51ZFHX1BZFHX1B
Entrez,  Source
zinc finger homeobox 1b38020.0330.4298No
52PPAP2APPAP2A
Entrez,  Source
phosphatidic acid phosphatase type 2A38510.0330.4287No
53ASAH1ASAH1
Entrez,  Source
N-acylsphingosine amidohydrolase (acid ceramidase) 139040.0320.4272No
54ALDH6A1ALDH6A1
Entrez,  Source
aldehyde dehydrogenase 6 family, member A143550.0250.3951No
55ATP1A1ATP1A1
Entrez,  Source
ATPase, Na+/K+ transporting, alpha 1 polypeptide46400.0200.3753No
56IL1R1IL1R1
Entrez,  Source
interleukin 1 receptor, type I46660.0200.3750No
57KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)46940.0200.3745No
58ATP1B1ATP1B1
Entrez,  Source
ATPase, Na+/K+ transporting, beta 1 polypeptide47880.0180.3689No
59DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)50070.0150.3536No
60CEBPDCEBPD
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), delta52680.0120.3348No
61TGFBR2TGFBR2
Entrez,  Source
transforming growth factor, beta receptor II (70/80kDa)52980.0110.3335No
62CTSHCTSH
Entrez,  Source
cathepsin H53870.0100.3276No
63BPGMBPGM
Entrez,  Source
2,3-bisphosphoglycerate mutase56000.0070.3122No
64HRSP12HRSP12
Entrez,  Source
heat-responsive protein 1256210.0070.3112No
65AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase56490.0060.3096No
66GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha57880.0050.2996No
67PLS3PLS3
Entrez,  Source
plastin 3 (T isoform)58530.0040.2950No
68MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase59550.0030.2876No
69FPGTFPGT
Entrez,  Source
fucose-1-phosphate guanylyltransferase59680.0030.2869No
70SLC37A4SLC37A4
Entrez,  Source
solute carrier family 37 (glycerol-6-phosphate transporter), member 46249-0.0010.2659No
71FAM3CFAM3C
Entrez,  Source
family with sequence similarity 3, member C6544-0.0050.2440No
72SDHDSDHD
Entrez,  Source
succinate dehydrogenase complex, subunit D, integral membrane protein6671-0.0070.2350No
73PDE8APDE8A
Entrez,  Source
phosphodiesterase 8A6843-0.0090.2228No
74TCF21TCF21
Entrez,  Source
transcription factor 216846-0.0090.2233No
75ERGERG
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog (avian)6929-0.0100.2179No
76SEPP1SEPP1
Entrez,  Source
selenoprotein P, plasma, 16950-0.0100.2171No
77ITM2BITM2B
Entrez,  Source
integral membrane protein 2B7038-0.0110.2114No
78UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase7435-0.0160.1828No
79TOB1TOB1
Entrez,  Source
transducer of ERBB2, 18322-0.0280.1180No
80PGRMC2PGRMC2
Entrez,  Source
progesterone receptor membrane component 28438-0.0300.1116No
81SLC35A3SLC35A3
Entrez,  Source
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A38545-0.0310.1061No
82CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)8731-0.0340.0948No
83SEPHS2SEPHS2
Entrez,  Source
selenophosphate synthetase 28918-0.0360.0836No
84SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 18926-0.0360.0859No
85HPNHPN
Entrez,  Source
hepsin (transmembrane protease, serine 1)8962-0.0370.0861No
86ANGPT1ANGPT1
Entrez,  Source
angiopoietin 19136-0.0390.0761No
87ANK3ANK3
Entrez,  Source
ankyrin 3, node of Ranvier (ankyrin G)9444-0.0440.0564No
88GNG12GNG12
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma 129617-0.0470.0471No
89APOMAPOM
Entrez,  Source
apolipoprotein M9750-0.0490.0410No
90GNG11GNG11
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma 119846-0.0510.0378No
91MAGI2MAGI2
Entrez,  Source
membrane associated guanylate kinase, WW and PDZ domain containing 210184-0.0560.0167No
92CRYZCRYZ
Entrez,  Source
crystallin, zeta (quinone reductase)10382-0.0600.0065No
93ST3GAL6ST3GAL6
Entrez,  Source
ST3 beta-galactoside alpha-2,3-sialyltransferase 610450-0.0610.0063No
94PLAUPLAU
Entrez,  Source
plasminogen activator, urokinase10548-0.0630.0039No
95VEGFVEGF
Entrez,  Source
vascular endothelial growth factor10686-0.066-0.0013No
96IFIT1IFIT1
Entrez,  Source
interferon-induced protein with tetratricopeptide repeats 111053-0.074-0.0232No
97SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like11182-0.078-0.0267No
98NR3C1NR3C1
Entrez,  Source
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)11271-0.081-0.0271No
99ELF1ELF1
Entrez,  Source
E74-like factor 1 (ets domain transcription factor)11340-0.083-0.0258No
100NCOA3NCOA3
Entrez,  Source
nuclear receptor coactivator 311477-0.086-0.0293No
101PODXLPODXL
Entrez,  Source
podocalyxin-like12132-0.109-0.0703No
102AGRINAGRIN
Entrez,  Source
agrin12183-0.111-0.0654No
103LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog12283-0.115-0.0638No
104MYH9MYH9
Entrez,  Source
myosin, heavy chain 9, non-muscle12494-0.127-0.0698No
105XBP1XBP1
Entrez,  Source
X-box binding protein 112661-0.138-0.0715No
106FGFR3FGFR3
Entrez,  Source
fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)12848-0.158-0.0731No
107PRPS2PRPS2
Entrez,  Source
phosphoribosyl pyrophosphate synthetase 212857-0.160-0.0613No
108ACSM3ACSM3
Entrez,  Source
acyl-CoA synthetase medium-chain family member 313224-0.273-0.0676No
109SLC30A1SLC30A1
Entrez,  Source
solute carrier family 30 (zinc transporter), member 113228-0.276-0.0462No
110VLDLRVLDLR
Entrez,  Source
very low density lipoprotein receptor13265-0.315-0.0242No
111PPP1R3CPPP1R3C
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 3C13293-0.3830.0037No
Table: GSEA details [plain text format]



Fig 2: LI_FETAL_VS_WT_KIDNEY_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: LI_FETAL_VS_WT_KIDNEY_UP: Random ES distribution   
Gene set null distribution of ES for LI_FETAL_VS_WT_KIDNEY_UP