Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | MOREAUX_TACI_HI_VS_LOW_DN |
| Enrichment Score (ES) | -0.4426774 |
| Normalized Enrichment Score (NES) | -1.5887294 |
| Nominal p-value | 0.004914005 |
| FDR q-value | 0.21989764 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 832 | 0.136 | -0.0341 | No |
| 2 | IHPK2 | IHPK2 Entrez, Source | inositol hexaphosphate kinase 2 | 835 | 0.136 | -0.0058 | No |
| 3 | TRIB1 | TRIB1 Entrez, Source | tribbles homolog 1 (Drosophila) | 1067 | 0.116 | 0.0012 | No |
| 4 | IREB2 | IREB2 Entrez, Source | iron-responsive element binding protein 2 | 1211 | 0.109 | 0.0132 | No |
| 5 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 1434 | 0.097 | 0.0167 | No |
| 6 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 1672 | 0.086 | 0.0169 | No |
| 7 | TMEM165 | TMEM165 Entrez, Source | transmembrane protein 165 | 1933 | 0.075 | 0.0130 | No |
| 8 | C3ORF64 | C3ORF64 Entrez, Source | chromosome 3 open reading frame 64 | 1963 | 0.074 | 0.0264 | No |
| 9 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 2441 | 0.061 | 0.0032 | No |
| 10 | MINPP1 | MINPP1 Entrez, Source | multiple inositol polyphosphate histidine phosphatase, 1 | 3052 | 0.047 | -0.0327 | No |
| 11 | WDR61 | WDR61 Entrez, Source | WD repeat domain 61 | 4368 | 0.024 | -0.1267 | No |
| 12 | PSMC4 | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 4709 | 0.019 | -0.1482 | No |
| 13 | NMT1 | NMT1 Entrez, Source | N-myristoyltransferase 1 | 4905 | 0.017 | -0.1594 | No |
| 14 | NADSYN1 | NADSYN1 Entrez, Source | NAD synthetase 1 | 5953 | 0.003 | -0.2377 | No |
| 15 | UPF3A | UPF3A Entrez, Source | UPF3 regulator of nonsense transcripts homolog A (yeast) | 6085 | 0.001 | -0.2474 | No |
| 16 | STAM2 | STAM2 Entrez, Source | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 6329 | -0.002 | -0.2652 | No |
| 17 | NCLN | NCLN Entrez, Source | nicalin homolog (zebrafish) | 6359 | -0.003 | -0.2668 | No |
| 18 | FIBP | FIBP Entrez, Source | fibroblast growth factor (acidic) intracellular binding protein | 7184 | -0.013 | -0.3262 | No |
| 19 | BUB3 | BUB3 Entrez, Source | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) | 7602 | -0.018 | -0.3538 | No |
| 20 | RAN | RAN Entrez, Source | RAN, member RAS oncogene family | 7972 | -0.023 | -0.3767 | No |
| 21 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 7980 | -0.023 | -0.3724 | No |
| 22 | IFT74 | IFT74 Entrez, Source | intraflagellar transport 74 homolog (Chlamydomonas) | 8022 | -0.024 | -0.3705 | No |
| 23 | CCT2 | CCT2 Entrez, Source | chaperonin containing TCP1, subunit 2 (beta) | 8167 | -0.026 | -0.3759 | No |
| 24 | ZCCHC10 | ZCCHC10 Entrez, Source | zinc finger, CCHC domain containing 10 | 8571 | -0.032 | -0.3995 | No |
| 25 | GCSH | GCSH Entrez, Source | glycine cleavage system protein H (aminomethyl carrier) | 8961 | -0.037 | -0.4211 | No |
| 26 | HNRPAB | HNRPAB Entrez, Source | heterogeneous nuclear ribonucleoprotein A/B | 9101 | -0.039 | -0.4234 | No |
| 27 | SSBP1 | SSBP1 Entrez, Source | single-stranded DNA binding protein 1 | 9358 | -0.043 | -0.4337 | Yes |
| 28 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 9386 | -0.043 | -0.4267 | Yes |
| 29 | CCT5 | CCT5 Entrez, Source | chaperonin containing TCP1, subunit 5 (epsilon) | 9486 | -0.045 | -0.4248 | Yes |
| 30 | SLC33A1 | SLC33A1 Entrez, Source | solute carrier family 33 (acetyl-CoA transporter), member 1 | 9585 | -0.047 | -0.4224 | Yes |
| 31 | G3BP | G3BP Entrez, Source | - | 9801 | -0.050 | -0.4281 | Yes |
| 32 | KEAP1 | KEAP1 Entrez, Source | kelch-like ECH-associated protein 1 | 9860 | -0.051 | -0.4217 | Yes |
| 33 | MATR3 | MATR3 Entrez, Source | matrin 3 | 9874 | -0.051 | -0.4119 | Yes |
| 34 | MRPL19 | MRPL19 Entrez, Source | mitochondrial ribosomal protein L19 | 10051 | -0.054 | -0.4138 | Yes |
| 35 | IK | IK Entrez, Source | IK cytokine, down-regulator of HLA II | 10126 | -0.056 | -0.4077 | Yes |
| 36 | RUVBL2 | RUVBL2 Entrez, Source | RuvB-like 2 (E. coli) | 10227 | -0.057 | -0.4033 | Yes |
| 37 | DARS | DARS Entrez, Source | aspartyl-tRNA synthetase | 10246 | -0.057 | -0.3926 | Yes |
| 38 | SMARCA4 | SMARCA4 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 10677 | -0.066 | -0.4112 | Yes |
| 39 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 10993 | -0.073 | -0.4196 | Yes |
| 40 | CIRH1A | CIRH1A Entrez, Source | cirrhosis, autosomal recessive 1A (cirhin) | 11001 | -0.073 | -0.4048 | Yes |
| 41 | MINA | MINA Entrez, Source | MYC induced nuclear antigen | 11107 | -0.076 | -0.3968 | Yes |
| 42 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 11170 | -0.077 | -0.3852 | Yes |
| 43 | EIF3S4 | EIF3S4 Entrez, Source | eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa | 11289 | -0.081 | -0.3771 | Yes |
| 44 | DDX18 | DDX18 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 11433 | -0.085 | -0.3702 | Yes |
| 45 | C1QBP | C1QBP Entrez, Source | complement component 1, q subcomponent binding protein | 11506 | -0.086 | -0.3575 | Yes |
| 46 | EBNA1BP2 | EBNA1BP2 Entrez, Source | EBNA1 binding protein 2 | 11605 | -0.089 | -0.3462 | Yes |
| 47 | NUDCD2 | NUDCD2 Entrez, Source | NudC domain containing 2 | 11804 | -0.096 | -0.3411 | Yes |
| 48 | ACTL6A | ACTL6A Entrez, Source | actin-like 6A | 11873 | -0.098 | -0.3256 | Yes |
| 49 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 11880 | -0.098 | -0.3054 | Yes |
| 50 | TAF2 | TAF2 Entrez, Source | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 11894 | -0.099 | -0.2857 | Yes |
| 51 | CDC23 | CDC23 Entrez, Source | CDC23 (cell division cycle 23, yeast, homolog) | 11974 | -0.102 | -0.2703 | Yes |
| 52 | SLC16A1 | SLC16A1 Entrez, Source | solute carrier family 16, member 1 (monocarboxylic acid transporter 1) | 12082 | -0.106 | -0.2561 | Yes |
| 53 | BTBD1 | BTBD1 Entrez, Source | BTB (POZ) domain containing 1 | 12240 | -0.113 | -0.2442 | Yes |
| 54 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 12396 | -0.121 | -0.2305 | Yes |
| 55 | PAPD4 | PAPD4 Entrez, Source | PAP associated domain containing 4 | 12428 | -0.123 | -0.2072 | Yes |
| 56 | CCDC5 | CCDC5 Entrez, Source | coiled-coil domain containing 5 (spindle associated) | 12482 | -0.127 | -0.1846 | Yes |
| 57 | NUDT5 | NUDT5 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 5 | 12497 | -0.127 | -0.1590 | Yes |
| 58 | THYN1 | THYN1 Entrez, Source | thymocyte nuclear protein 1 | 12592 | -0.134 | -0.1380 | Yes |
| 59 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12652 | -0.138 | -0.1136 | Yes |
| 60 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12677 | -0.140 | -0.0861 | Yes |
| 61 | GLT8D1 | GLT8D1 Entrez, Source | glycosyltransferase 8 domain containing 1 | 12783 | -0.150 | -0.0626 | Yes |
| 62 | CEP57 | CEP57 Entrez, Source | centrosomal protein 57kDa | 12793 | -0.151 | -0.0315 | Yes |
| 63 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 12945 | -0.172 | -0.0068 | Yes |
| 64 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 12964 | -0.175 | 0.0285 | Yes |
