Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | MRNA_PROCESSING |
| Enrichment Score (ES) | -0.54530615 |
| Normalized Enrichment Score (NES) | -1.5786074 |
| Nominal p-value | 0.026584867 |
| FDR q-value | 0.20866185 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 977 | 0.123 | 0.0098 | No |
| 2 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 3618 | 0.037 | -0.1638 | No |
| 3 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 3810 | 0.033 | -0.1557 | No |
| 4 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 4679 | 0.020 | -0.2074 | No |
| 5 | SLU7 | SLU7 Entrez, Source | - | 4976 | 0.016 | -0.2192 | No |
| 6 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 5567 | 0.007 | -0.2585 | No |
| 7 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 6720 | -0.007 | -0.3400 | No |
| 8 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 7120 | -0.012 | -0.3618 | No |
| 9 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 7205 | -0.013 | -0.3593 | No |
| 10 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 7775 | -0.020 | -0.3882 | No |
| 11 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8111 | -0.025 | -0.3964 | No |
| 12 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 10069 | -0.055 | -0.5066 | Yes |
| 13 | PRPF8 | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 10586 | -0.064 | -0.5023 | Yes |
| 14 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 10794 | -0.068 | -0.4719 | Yes |
| 15 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 10849 | -0.070 | -0.4290 | Yes |
| 16 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11343 | -0.083 | -0.4104 | Yes |
| 17 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 11513 | -0.087 | -0.3647 | Yes |
| 18 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 11660 | -0.090 | -0.3148 | Yes |
| 19 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 11792 | -0.095 | -0.2604 | Yes |
| 20 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 11902 | -0.099 | -0.2017 | Yes |
| 21 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13096 | -0.208 | -0.1511 | Yes |
| 22 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 13196 | -0.252 | 0.0110 | Yes |
