Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | MRNA_PROCESSING_GO_0006397 |
| Enrichment Score (ES) | -0.53468585 |
| Normalized Enrichment Score (NES) | -1.6870881 |
| Nominal p-value | 0.006423983 |
| FDR q-value | 0.16614953 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 977 | 0.123 | -0.0164 | No |
| 2 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1068 | 0.116 | 0.0306 | No |
| 3 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 3810 | 0.033 | -0.1599 | No |
| 4 | SLU7 | SLU7 Entrez, Source | - | 4976 | 0.016 | -0.2403 | No |
| 5 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 5567 | 0.007 | -0.2812 | No |
| 6 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6461 | -0.004 | -0.3465 | No |
| 7 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 6720 | -0.007 | -0.3624 | No |
| 8 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 7120 | -0.012 | -0.3868 | No |
| 9 | SF3A2 | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 7150 | -0.012 | -0.3832 | No |
| 10 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 7205 | -0.013 | -0.3812 | No |
| 11 | GRSF1 | GRSF1 Entrez, Source | G-rich RNA sequence binding factor 1 | 7484 | -0.016 | -0.3945 | No |
| 12 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 7775 | -0.020 | -0.4069 | No |
| 13 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8111 | -0.025 | -0.4204 | No |
| 14 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 8696 | -0.034 | -0.4488 | No |
| 15 | CPSF3 | CPSF3 Entrez, Source | cleavage and polyadenylation specific factor 3, 73kDa | 8954 | -0.037 | -0.4510 | No |
| 16 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 10069 | -0.055 | -0.5094 | Yes |
| 17 | GEMIN6 | GEMIN6 Entrez, Source | gem (nuclear organelle) associated protein 6 | 10170 | -0.056 | -0.4909 | Yes |
| 18 | CRNKL1 | CRNKL1 Entrez, Source | Crn, crooked neck-like 1 (Drosophila) | 10445 | -0.061 | -0.4833 | Yes |
| 19 | CDC2L1 | CDC2L1 Entrez, Source | cell division cycle 2-like 1 (PITSLRE proteins) | 10741 | -0.067 | -0.4744 | Yes |
| 20 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 10794 | -0.068 | -0.4468 | Yes |
| 21 | SRPK1 | SRPK1 Entrez, Source | SFRS protein kinase 1 | 10895 | -0.071 | -0.4217 | Yes |
| 22 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 10990 | -0.073 | -0.3950 | Yes |
| 23 | DDX20 | DDX20 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 11083 | -0.075 | -0.3671 | Yes |
| 24 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 11170 | -0.077 | -0.3378 | Yes |
| 25 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 11203 | -0.078 | -0.3039 | Yes |
| 26 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11343 | -0.083 | -0.2762 | Yes |
| 27 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 11513 | -0.087 | -0.2488 | Yes |
| 28 | DDX39 | DDX39 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 | 11591 | -0.089 | -0.2136 | Yes |
| 29 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 11660 | -0.090 | -0.1769 | Yes |
| 30 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 11792 | -0.095 | -0.1427 | Yes |
| 31 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 11902 | -0.099 | -0.1050 | Yes |
| 32 | CSTF1 | CSTF1 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 11951 | -0.101 | -0.0620 | Yes |
| 33 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12122 | -0.108 | -0.0247 | Yes |
| 34 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 13196 | -0.252 | 0.0110 | Yes |
