Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | MRNA_PROCESSING_REACTOME |
| Enrichment Score (ES) | -0.47028187 |
| Normalized Enrichment Score (NES) | -1.7038345 |
| Nominal p-value | 0.004750594 |
| FDR q-value | 0.19018424 |
| FWER p-Value | 0.998 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 389 | 0.213 | 0.0274 | No |
| 2 | HNRPA3 | HNRPA3 Entrez, Source | heterogeneous nuclear ribonucleoprotein A3 | 1631 | 0.088 | -0.0427 | No |
| 3 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 2854 | 0.052 | -0.1210 | No |
| 4 | DNAJC8 | DNAJC8 Entrez, Source | DnaJ (Hsp40) homolog, subfamily C, member 8 | 3556 | 0.038 | -0.1637 | No |
| 5 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 3618 | 0.037 | -0.1586 | No |
| 6 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 3810 | 0.033 | -0.1641 | No |
| 7 | GIPC1 | GIPC1 Entrez, Source | GIPC PDZ domain containing family, member 1 | 4151 | 0.028 | -0.1823 | No |
| 8 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 4679 | 0.020 | -0.2167 | No |
| 9 | SF3B1 | SF3B1 Entrez, Source | splicing factor 3b, subunit 1, 155kDa | 4753 | 0.019 | -0.2171 | No |
| 10 | SUPT5H | SUPT5H Entrez, Source | suppressor of Ty 5 homolog (S. cerevisiae) | 5215 | 0.012 | -0.2485 | No |
| 11 | CUGBP2 | CUGBP2 Entrez, Source | CUG triplet repeat, RNA binding protein 2 | 5461 | 0.009 | -0.2646 | No |
| 12 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 5569 | 0.007 | -0.2707 | No |
| 13 | CLK3 | CLK3 Entrez, Source | CDC-like kinase 3 | 6374 | -0.003 | -0.3305 | No |
| 14 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6461 | -0.004 | -0.3359 | No |
| 15 | SF4 | SF4 Entrez, Source | splicing factor 4 | 6480 | -0.004 | -0.3362 | No |
| 16 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 6720 | -0.007 | -0.3522 | No |
| 17 | PPM1G | PPM1G Entrez, Source | protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform | 6810 | -0.008 | -0.3567 | No |
| 18 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 7120 | -0.012 | -0.3767 | No |
| 19 | SF3A2 | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 7150 | -0.012 | -0.3756 | No |
| 20 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 7205 | -0.013 | -0.3762 | No |
| 21 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 7584 | -0.018 | -0.3999 | No |
| 22 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 7775 | -0.020 | -0.4088 | No |
| 23 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 7790 | -0.021 | -0.4043 | No |
| 24 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8111 | -0.025 | -0.4217 | No |
| 25 | CLK4 | CLK4 Entrez, Source | CDC-like kinase 4 | 8518 | -0.031 | -0.4440 | No |
| 26 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 8696 | -0.034 | -0.4484 | No |
| 27 | CPSF3 | CPSF3 Entrez, Source | cleavage and polyadenylation specific factor 3, 73kDa | 8954 | -0.037 | -0.4579 | Yes |
| 28 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 8997 | -0.038 | -0.4511 | Yes |
| 29 | PABPN1 | PABPN1 Entrez, Source | poly(A) binding protein, nuclear 1 | 9064 | -0.038 | -0.4459 | Yes |
| 30 | HNRPAB | HNRPAB Entrez, Source | heterogeneous nuclear ribonucleoprotein A/B | 9101 | -0.039 | -0.4382 | Yes |
| 31 | HNRPC | HNRPC Entrez, Source | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 9106 | -0.039 | -0.4282 | Yes |
| 32 | DHX8 | DHX8 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 9187 | -0.040 | -0.4235 | Yes |
| 33 | RBM5 | RBM5 Entrez, Source | RNA binding motif protein 5 | 9487 | -0.045 | -0.4341 | Yes |
| 34 | PRPF4 | PRPF4 Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog (yeast) | 9579 | -0.046 | -0.4286 | Yes |
| 35 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 10069 | -0.055 | -0.4508 | Yes |
| 36 | DHX16 | DHX16 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 10268 | -0.058 | -0.4503 | Yes |
| 37 | NXF1 | NXF1 Entrez, Source | nuclear RNA export factor 1 | 10534 | -0.063 | -0.4535 | Yes |
| 38 | METTL3 | METTL3 Entrez, Source | methyltransferase like 3 | 10544 | -0.063 | -0.4374 | Yes |
| 39 | HNRPL | HNRPL Entrez, Source | heterogeneous nuclear ribonucleoprotein L | 10566 | -0.064 | -0.4221 | Yes |
| 40 | PRPF8 | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 10586 | -0.064 | -0.4065 | Yes |
| 41 | SNRPN | SNRPN Entrez, Source | small nuclear ribonucleoprotein polypeptide N | 10762 | -0.067 | -0.4017 | Yes |
| 42 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 10849 | -0.070 | -0.3897 | Yes |
| 43 | SRPK1 | SRPK1 Entrez, Source | SFRS protein kinase 1 | 10895 | -0.071 | -0.3743 | Yes |
| 44 | RBM17 | RBM17 Entrez, Source | RNA binding motif protein 17 | 10968 | -0.073 | -0.3604 | Yes |
| 45 | DDX20 | DDX20 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 11083 | -0.075 | -0.3489 | Yes |
| 46 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 11203 | -0.078 | -0.3371 | Yes |
| 47 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11343 | -0.083 | -0.3255 | Yes |
| 48 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 11660 | -0.090 | -0.3253 | Yes |
| 49 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 11792 | -0.095 | -0.3098 | Yes |
| 50 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 11880 | -0.098 | -0.2901 | Yes |
| 51 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 11902 | -0.099 | -0.2653 | Yes |
| 52 | CSTF1 | CSTF1 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 11951 | -0.101 | -0.2421 | Yes |
| 53 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12122 | -0.108 | -0.2261 | Yes |
| 54 | HNRPH1 | HNRPH1 Entrez, Source | heterogeneous nuclear ribonucleoprotein H1 (H) | 12186 | -0.111 | -0.2013 | Yes |
| 55 | FUS | FUS Entrez, Source | fusion (involved in t(12;16) in malignant liposarcoma) | 12205 | -0.112 | -0.1730 | Yes |
| 56 | PTBP2 | PTBP2 Entrez, Source | polypyrimidine tract binding protein 2 | 12364 | -0.119 | -0.1532 | Yes |
| 57 | HNRPU | HNRPU Entrez, Source | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 12429 | -0.123 | -0.1254 | Yes |
| 58 | SNRPN /// SNURF | 12618 | -0.136 | -0.1034 | Yes | ||
| 59 | SNRPA | SNRPA Entrez, Source | small nuclear ribonucleoprotein polypeptide A | 12683 | -0.140 | -0.0709 | Yes |
| 60 | DICER1 | DICER1 Entrez, Source | Dicer1, Dcr-1 homolog (Drosophila) | 13152 | -0.225 | -0.0462 | Yes |
| 61 | DDIT3 | DDIT3 Entrez, Source | DNA-damage-inducible transcript 3 | 13156 | -0.227 | 0.0140 | Yes |
