Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | NETPATH_ANDROGEN_RECEPTOR_PATHWAY_DOWN |
| Enrichment Score (ES) | 0.49187678 |
| Normalized Enrichment Score (NES) | 1.7991856 |
| Nominal p-value | 0.0016611295 |
| FDR q-value | 0.032256823 |
| FWER p-Value | 0.969 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CYP17A1 | CYP17A1 Entrez, Source | cytochrome P450, family 17, subfamily A, polypeptide 1 | 8 | 0.860 | 0.0700 | Yes |
| 2 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 11 | 0.815 | 0.1368 | Yes |
| 3 | LPL | LPL Entrez, Source | lipoprotein lipase | 24 | 0.680 | 0.1917 | Yes |
| 4 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 28 | 0.668 | 0.2463 | Yes |
| 5 | TIMP2 | TIMP2 Entrez, Source | TIMP metallopeptidase inhibitor 2 | 35 | 0.642 | 0.2986 | Yes |
| 6 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 145 | 0.367 | 0.3204 | Yes |
| 7 | CRAT | CRAT Entrez, Source | carnitine acetyltransferase | 170 | 0.348 | 0.3472 | Yes |
| 8 | PKIB | PKIB Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor beta | 237 | 0.292 | 0.3661 | Yes |
| 9 | JAG1 | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 323 | 0.239 | 0.3793 | Yes |
| 10 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 326 | 0.238 | 0.3987 | Yes |
| 11 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 367 | 0.223 | 0.4140 | Yes |
| 12 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 372 | 0.219 | 0.4317 | Yes |
| 13 | CX3CL1 | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 375 | 0.218 | 0.4494 | Yes |
| 14 | JUN | JUN Entrez, Source | jun oncogene | 458 | 0.194 | 0.4591 | Yes |
| 15 | CUTL1 | CUTL1 Entrez, Source | cut-like 1, CCAAT displacement protein (Drosophila) | 516 | 0.180 | 0.4696 | Yes |
| 16 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 567 | 0.170 | 0.4798 | Yes |
| 17 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 832 | 0.136 | 0.4710 | Yes |
| 18 | ACAT1 | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 990 | 0.123 | 0.4692 | Yes |
| 19 | RALB | RALB Entrez, Source | v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) | 1019 | 0.120 | 0.4769 | Yes |
| 20 | ERBB2 | ERBB2 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 1072 | 0.116 | 0.4825 | Yes |
| 21 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 1105 | 0.114 | 0.4895 | Yes |
| 22 | CAMK2N2 | CAMK2N2 Entrez, Source | calcium/calmodulin-dependent protein kinase II inhibitor 2 | 1252 | 0.107 | 0.4872 | Yes |
| 23 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 1492 | 0.094 | 0.4769 | Yes |
| 24 | NUCB2 | NUCB2 Entrez, Source | nucleobindin 2 | 1503 | 0.094 | 0.4839 | Yes |
| 25 | PLA2G2A | PLA2G2A Entrez, Source | phospholipase A2, group IIA (platelets, synovial fluid) | 1578 | 0.090 | 0.4857 | Yes |
| 26 | HMGCL | HMGCL Entrez, Source | 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria) | 1594 | 0.089 | 0.4919 | Yes |
| 27 | P2RY2 | P2RY2 Entrez, Source | purinergic receptor P2Y, G-protein coupled, 2 | 1862 | 0.078 | 0.4781 | No |
| 28 | P4HA1 | P4HA1 Entrez, Source | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I | 2075 | 0.071 | 0.4679 | No |
| 29 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 2079 | 0.071 | 0.4734 | No |
| 30 | AGC1 | AGC1 Entrez, Source | aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) | 2474 | 0.060 | 0.4486 | No |
| 31 | STXBP1 | STXBP1 Entrez, Source | syntaxin binding protein 1 | 2596 | 0.058 | 0.4442 | No |
| 32 | FN1 | FN1 Entrez, Source | fibronectin 1 | 2637 | 0.057 | 0.4458 | No |
| 33 | NFIX | NFIX Entrez, Source | nuclear factor I/X (CCAAT-binding transcription factor) | 2946 | 0.050 | 0.4266 | No |
| 34 | OXT | OXT Entrez, Source | oxytocin, prepro- (neurophysin I) | 3031 | 0.048 | 0.4242 | No |
| 35 | MINPP1 | MINPP1 Entrez, Source | multiple inositol polyphosphate histidine phosphatase, 1 | 3052 | 0.047 | 0.4266 | No |
| 36 | SDC4 | SDC4 Entrez, Source | syndecan 4 (amphiglycan, ryudocan) | 3195 | 0.045 | 0.4195 | No |
| 37 | SQSTM1 | SQSTM1 Entrez, Source | sequestosome 1 | 3270 | 0.043 | 0.4175 | No |
| 38 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 3274 | 0.043 | 0.4208 | No |
| 39 | CLU | CLU Entrez, Source | clusterin | 3299 | 0.043 | 0.4225 | No |
| 40 | SNX1 | SNX1 Entrez, Source | sorting nexin 1 | 3339 | 0.042 | 0.4229 | No |
| 41 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 3391 | 0.041 | 0.4224 | No |
| 42 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 3414 | 0.040 | 0.4241 | No |
| 43 | SMPD1 | SMPD1 Entrez, Source | sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase) | 3434 | 0.040 | 0.4259 | No |
| 44 | PDK2 | PDK2 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 2 | 3456 | 0.040 | 0.4275 | No |
| 45 | CTBP1 | CTBP1 Entrez, Source | C-terminal binding protein 1 | 3848 | 0.033 | 0.4007 | No |
| 46 | GRN | GRN Entrez, Source | granulin | 3902 | 0.032 | 0.3993 | No |
| 47 | BSG | BSG Entrez, Source | basigin (Ok blood group) | 3928 | 0.031 | 0.4000 | No |
| 48 | TXNIP | TXNIP Entrez, Source | thioredoxin interacting protein | 3975 | 0.031 | 0.3990 | No |
| 49 | GLI3 | GLI3 Entrez, Source | GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome) | 4066 | 0.029 | 0.3946 | No |
| 50 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 4251 | 0.026 | 0.3828 | No |
| 51 | PAMCI | PAMCI Entrez, Source | peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor | 4324 | 0.025 | 0.3794 | No |
| 52 | CACNB3 | CACNB3 Entrez, Source | calcium channel, voltage-dependent, beta 3 subunit | 4613 | 0.021 | 0.3594 | No |
| 53 | FLOT2 | FLOT2 Entrez, Source | flotillin 2 | 4869 | 0.017 | 0.3415 | No |
| 54 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 4953 | 0.016 | 0.3365 | No |
| 55 | PPP2R2A | PPP2R2A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform | 4968 | 0.016 | 0.3368 | No |
| 56 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 5035 | 0.015 | 0.3330 | No |
| 57 | SULT2A1 | SULT2A1 Entrez, Source | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 5283 | 0.011 | 0.3153 | No |
| 58 | ATP2B1 | ATP2B1 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 1 | 5288 | 0.011 | 0.3159 | No |
| 59 | SCNN1A | SCNN1A Entrez, Source | sodium channel, nonvoltage-gated 1 alpha | 5333 | 0.011 | 0.3134 | No |
| 60 | SERPINI1 | SERPINI1 Entrez, Source | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 5393 | 0.010 | 0.3098 | No |
| 61 | SFRP4 | SFRP4 Entrez, Source | secreted frizzled-related protein 4 | 5484 | 0.009 | 0.3037 | No |
| 62 | PAM | PAM Entrez, Source | peptidylglycine alpha-amidating monooxygenase | 5501 | 0.008 | 0.3032 | No |
| 63 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 6001 | 0.002 | 0.2656 | No |
| 64 | NOTCH1 | NOTCH1 Entrez, Source | Notch homolog 1, translocation-associated (Drosophila) | 6141 | 0.000 | 0.2551 | No |
| 65 | ENO2 | ENO2 Entrez, Source | enolase 2 (gamma, neuronal) | 6221 | -0.001 | 0.2492 | No |
| 66 | HRG | HRG Entrez, Source | histidine-rich glycoprotein | 6224 | -0.001 | 0.2492 | No |
| 67 | CNTFR | CNTFR Entrez, Source | ciliary neurotrophic factor receptor | 6526 | -0.005 | 0.2268 | No |
| 68 | LRRN1 | LRRN1 Entrez, Source | leucine rich repeat neuronal 1 | 6617 | -0.006 | 0.2205 | No |
| 69 | PDYN | PDYN Entrez, Source | prodynorphin | 6659 | -0.007 | 0.2179 | No |
| 70 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 6663 | -0.007 | 0.2182 | No |
| 71 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 6734 | -0.007 | 0.2136 | No |
| 72 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 6766 | -0.008 | 0.2119 | No |
| 73 | KLK3 | KLK3 Entrez, Source | kallikrein 3, (prostate specific antigen) | 6910 | -0.010 | 0.2018 | No |
| 74 | ACPP | ACPP Entrez, Source | acid phosphatase, prostate | 7380 | -0.015 | 0.1676 | No |
| 75 | CAMK2N1 | CAMK2N1 Entrez, Source | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 7381 | -0.015 | 0.1689 | No |
| 76 | KIF5B | KIF5B Entrez, Source | kinesin family member 5B | 7649 | -0.019 | 0.1502 | No |
| 77 | GCHFR | GCHFR Entrez, Source | GTP cyclohydrolase I feedback regulator | 7685 | -0.019 | 0.1492 | No |
| 78 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 7715 | -0.020 | 0.1486 | No |
| 79 | PLEKHB1 | PLEKHB1 Entrez, Source | pleckstrin homology domain containing, family B (evectins) member 1 | 7867 | -0.022 | 0.1389 | No |
| 80 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 7976 | -0.023 | 0.1327 | No |
| 81 | STAR | STAR Entrez, Source | steroidogenic acute regulator | 8512 | -0.031 | 0.0948 | No |
| 82 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 8513 | -0.031 | 0.0973 | No |
| 83 | BAMBI | BAMBI Entrez, Source | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) | 8540 | -0.031 | 0.0979 | No |
| 84 | ACP6 | ACP6 Entrez, Source | acid phosphatase 6, lysophosphatidic | 8685 | -0.033 | 0.0898 | No |
| 85 | GATA2 | GATA2 Entrez, Source | GATA binding protein 2 | 8903 | -0.036 | 0.0764 | No |
| 86 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 9039 | -0.038 | 0.0693 | No |
| 87 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 9252 | -0.041 | 0.0566 | No |
| 88 | SMARCD3 | SMARCD3 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | 9321 | -0.042 | 0.0549 | No |
| 89 | ST7 | ST7 Entrez, Source | suppression of tumorigenicity 7 | 9348 | -0.042 | 0.0565 | No |
| 90 | RNASE4 | RNASE4 Entrez, Source | ribonuclease, RNase A family, 4 | 9382 | -0.043 | 0.0575 | No |
| 91 | CGA | CGA Entrez, Source | glycoprotein hormones, alpha polypeptide | 9437 | -0.044 | 0.0570 | No |
| 92 | PCTK1 | PCTK1 Entrez, Source | PCTAIRE protein kinase 1 | 9584 | -0.047 | 0.0498 | No |
| 93 | MBTPS1 | MBTPS1 Entrez, Source | membrane-bound transcription factor peptidase, site 1 | 9595 | -0.047 | 0.0529 | No |
| 94 | SNRK | SNRK Entrez, Source | SNF related kinase | 9708 | -0.049 | 0.0484 | No |
| 95 | COLEC12 | COLEC12 Entrez, Source | collectin sub-family member 12 | 9996 | -0.053 | 0.0311 | No |
| 96 | ACSL5 | ACSL5 Entrez, Source | acyl-CoA synthetase long-chain family member 5 | 10100 | -0.055 | 0.0279 | No |
| 97 | NET1 | NET1 Entrez, Source | neuroepithelial cell transforming gene 1 | 10614 | -0.065 | -0.0056 | No |
| 98 | PRKD1 | PRKD1 Entrez, Source | protein kinase D1 | 10693 | -0.066 | -0.0061 | No |
| 99 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 10954 | -0.072 | -0.0198 | No |
| 100 | ASNS | ASNS Entrez, Source | asparagine synthetase | 11024 | -0.074 | -0.0189 | No |
| 101 | FOXQ1 | FOXQ1 Entrez, Source | forkhead box Q1 | 11748 | -0.094 | -0.0659 | No |
| 102 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 11985 | -0.102 | -0.0754 | No |
| 103 | FZD3 | FZD3 Entrez, Source | frizzled homolog 3 (Drosophila) | 12326 | -0.117 | -0.0914 | No |
| 104 | MMP16 | MMP16 Entrez, Source | matrix metallopeptidase 16 (membrane-inserted) | 12615 | -0.135 | -0.1021 | No |
| 105 | SLC12A2 | SLC12A2 Entrez, Source | solute carrier family 12 (sodium/potassium/chloride transporters), member 2 | 12841 | -0.158 | -0.1061 | No |
| 106 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 13027 | -0.192 | -0.1043 | No |
| 107 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 13029 | -0.193 | -0.0885 | No |
| 108 | BCHE | BCHE Entrez, Source | butyrylcholinesterase | 13061 | -0.200 | -0.0745 | No |
| 109 | SLC44A1 | SLC44A1 Entrez, Source | solute carrier family 44, member 1 | 13078 | -0.203 | -0.0590 | No |
| 110 | CEBPA | CEBPA Entrez, Source | CCAAT/enhancer binding protein (C/EBP), alpha | 13105 | -0.210 | -0.0437 | No |
| 111 | SLC20A2 | SLC20A2 Entrez, Source | solute carrier family 20 (phosphate transporter), member 2 | 13149 | -0.225 | -0.0285 | No |
| 112 | GSTA2 | GSTA2 Entrez, Source | glutathione S-transferase A2 | 13322 | -0.524 | 0.0015 | No |
