Details for gene set NETPATH_EGFR1_PATHWAY

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in class	double_gel_8d
GeneSet	NETPATH_EGFR1_PATHWAY_UP
Enrichment Score (ES)	0.5654212
Normalized Enrichment Score (NES)	2.0300777
Nominal p-value	0.0
FDR q-value	0.0038256696
FWER p-Value	0.12

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	VIM	VIM Entrez, Source	vimentin	6	0.953	0.0890	Yes
2	ANXA1	ANXA1 Entrez, Source	annexin A1	10	0.815	0.1653	Yes
3	CTGF	CTGF Entrez, Source	connective tissue growth factor	32	0.660	0.2256	Yes
4	CORO1A	CORO1A Entrez, Source	coronin, actin binding protein, 1A	41	0.620	0.2831	Yes
5	EMP1	EMP1 Entrez, Source	epithelial membrane protein 1	44	0.606	0.3398	Yes
6	GPRC5A	GPRC5A Entrez, Source	G protein-coupled receptor, family C, group 5, member A	49	0.587	0.3946	Yes
7	TAGLN	TAGLN Entrez, Source	transgelin	253	0.280	0.4056	Yes
8	TGFB2	TGFB2 Entrez, Source	transforming growth factor, beta 2	367	0.223	0.4179	Yes
9	PLK2	PLK2 Entrez, Source	polo-like kinase 2 (Drosophila)	414	0.206	0.4338	Yes
10	MGLL	MGLL Entrez, Source	monoglyceride lipase	454	0.195	0.4491	Yes
11	SLC20A1	SLC20A1 Entrez, Source	solute carrier family 20 (phosphate transporter), member 1	543	0.173	0.4587	Yes
12	IER3	IER3 Entrez, Source	immediate early response 3	598	0.165	0.4701	Yes
13	AR	AR Entrez, Source	androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)	602	0.164	0.4853	Yes
14	MMP7	MMP7 Entrez, Source	matrix metallopeptidase 7 (matrilysin, uterine)	641	0.159	0.4973	Yes
15	SPRY2	SPRY2 Entrez, Source	sprouty homolog 2 (Drosophila)	663	0.156	0.5103	Yes
16	HBEGF	HBEGF Entrez, Source	heparin-binding EGF-like growth factor	717	0.149	0.5203	Yes
17	PHLDA1	PHLDA1 Entrez, Source	pleckstrin homology-like domain, family A, member 1	772	0.143	0.5296	Yes
18	HS3ST1	HS3ST1 Entrez, Source	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	830	0.136	0.5381	Yes
19	LIF	LIF Entrez, Source	leukemia inhibitory factor (cholinergic differentiation factor)	1037	0.118	0.5336	Yes
20	SPP1	SPP1 Entrez, Source	secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)	1105	0.114	0.5393	Yes
21	SNAI1	SNAI1 Entrez, Source	snail homolog 1 (Drosophila)	1130	0.113	0.5481	Yes
22	ZFP36L2	ZFP36L2 Entrez, Source	zinc finger protein 36, C3H type-like 2	1206	0.109	0.5527	Yes
23	DUSP1	DUSP1 Entrez, Source	dual specificity phosphatase 1	1297	0.104	0.5557	Yes
24	PLAUR	PLAUR Entrez, Source	plasminogen activator, urokinase receptor	1327	0.103	0.5631	Yes
25	BUB1B	BUB1B Entrez, Source	BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)	1499	0.094	0.5590	Yes
26	CDKN1B	CDKN1B Entrez, Source	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	1676	0.086	0.5538	Yes
27	ACOT7	ACOT7 Entrez, Source	acyl-CoA thioesterase 7	1681	0.086	0.5615	Yes
28	DKK3	DKK3 Entrez, Source	dickkopf homolog 3 (Xenopus laevis)	1742	0.083	0.5647	Yes
29	CXCL5	CXCL5 Entrez, Source	chemokine (C-X-C motif) ligand 5	1832	0.079	0.5654	Yes
30	FGFBP1	FGFBP1 Entrez, Source	fibroblast growth factor binding protein 1	2072	0.071	0.5540	No
31	CAV2	CAV2 Entrez, Source	caveolin 2	2151	0.069	0.5546	No
32	DUSP4	DUSP4 Entrez, Source	dual specificity phosphatase 4	2162	0.068	0.5602	No
33	CLDN4	CLDN4 Entrez, Source	claudin 4	2429	0.061	0.5459	No
34	CDK9	CDK9 Entrez, Source	cyclin-dependent kinase 9 (CDC2-related kinase)	2915	0.051	0.5140	No
35	NR4A3	NR4A3 Entrez, Source	nuclear receptor subfamily 4, group A, member 3	2974	0.049	0.5142	No
36	EREG	EREG Entrez, Source	epiregulin	2999	0.049	0.5169	No
37	SDC4	SDC4 Entrez, Source	syndecan 4 (amphiglycan, ryudocan)	3195	0.045	0.5064	No
38	EGR1	EGR1 Entrez, Source	early growth response 1	3274	0.043	0.5046	No
39	CYCS	CYCS Entrez, Source	cytochrome c, somatic	3372	0.041	0.5011	No
40	ITGB5	ITGB5 Entrez, Source	integrin, beta 5	3714	0.035	0.4786	No
41	ESR1	ESR1 Entrez, Source	estrogen receptor 1	3749	0.034	0.4793	No
42	MMP3	MMP3 Entrez, Source	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	3764	0.034	0.4814	No
43	TUBG1	TUBG1 Entrez, Source	tubulin, gamma 1	4212	0.027	0.4502	No
44	DUSP6	DUSP6 Entrez, Source	dual specificity phosphatase 6	4288	0.026	0.4469	No
45	HAS2	HAS2 Entrez, Source	hyaluronan synthase 2	4352	0.025	0.4445	No
46	HPCAL1	HPCAL1 Entrez, Source	hippocalcin-like 1	4353	0.025	0.4468	No
47	PTHLH	PTHLH Entrez, Source	parathyroid hormone-like hormone	4594	0.021	0.4307	No
48	SAA4	SAA4 Entrez, Source	serum amyloid A4, constitutive	4704	0.020	0.4243	No
49	MAPT	MAPT Entrez, Source	microtubule-associated protein tau	4748	0.019	0.4228	No
50	LCN2	LCN2 Entrez, Source	lipocalin 2 (oncogene 24p3)	4934	0.016	0.4103	No
51	MT3	MT3 Entrez, Source	metallothionein 3 (growth inhibitory factor (neurotrophic))	5102	0.014	0.3990	No
52	CDC42	CDC42 Entrez, Source	cell division cycle 42 (GTP binding protein, 25kDa)	5202	0.013	0.3928	No
53	GADD45A	GADD45A Entrez, Source	growth arrest and DNA-damage-inducible, alpha	5788	0.005	0.3490	No
54	FASLG	FASLG Entrez, Source	Fas ligand (TNF superfamily, member 6)	5984	0.002	0.3345	No
55	CCNC	CCNC Entrez, Source	cyclin C	5995	0.002	0.3340	No
56	MSLN	MSLN Entrez, Source	mesothelin	6309	-0.002	0.3105	No
57	EHD1	EHD1 Entrez, Source	EH-domain containing 1	6660	-0.007	0.2847	No
58	TFPI2	TFPI2 Entrez, Source	tissue factor pathway inhibitor 2	6771	-0.008	0.2772	No
59	NOS1	NOS1 Entrez, Source	nitric oxide synthase 1 (neuronal)	7163	-0.013	0.2488	No
60	AREG	AREG Entrez, Source	amphiregulin (schwannoma-derived growth factor)	7265	-0.014	0.2425	No
61	TGFA	TGFA Entrez, Source	transforming growth factor, alpha	7317	-0.014	0.2400	No
62	AKAP12	AKAP12 Entrez, Source	A kinase (PRKA) anchor protein (gravin) 12	7409	-0.015	0.2346	No
63	ZYX	ZYX Entrez, Source	zyxin	7461	-0.016	0.2322	No
64	MYC	MYC Entrez, Source	v-myc myelocytomatosis viral oncogene homolog (avian)	7715	-0.020	0.2150	No
65	CDKN1A	CDKN1A Entrez, Source	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	7976	-0.023	0.1975	No
66	HNRPK	HNRPK Entrez, Source	heterogeneous nuclear ribonucleoprotein K	8260	-0.027	0.1787	No
67	UBE2N	UBE2N Entrez, Source	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	8325	-0.028	0.1765	No
68	SERPINB2	SERPINB2 Entrez, Source	serpin peptidase inhibitor, clade B (ovalbumin), member 2	8340	-0.028	0.1781	No
69	CCND1	CCND1 Entrez, Source	cyclin D1	8524	-0.031	0.1672	No
70	BZW1	BZW1 Entrez, Source	basic leucine zipper and W2 domains 1	8626	-0.033	0.1627	No
71	TMEM97	TMEM97 Entrez, Source	transmembrane protein 97	8656	-0.033	0.1636	No
72	PRPS1	PRPS1 Entrez, Source	phosphoribosyl pyrophosphate synthetase 1	8663	-0.033	0.1662	No
73	UBE2A	UBE2A Entrez, Source	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	8758	-0.034	0.1623	No
74	PLCG1	PLCG1 Entrez, Source	phospholipase C, gamma 1	8898	-0.036	0.1552	No
75	HNRPAB	HNRPAB Entrez, Source	heterogeneous nuclear ribonucleoprotein A/B	9101	-0.039	0.1436	No
76	PPP1R10	PPP1R10 Entrez, Source	protein phosphatase 1, regulatory subunit 10	9190	-0.040	0.1407	No
77	PPP2R1A	PPP2R1A Entrez, Source	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	9245	-0.041	0.1405	No
78	IL4R	IL4R Entrez, Source	interleukin 4 receptor	9332	-0.042	0.1380	No
79	COMMD10	COMMD10 Entrez, Source	COMM domain containing 10	9470	-0.045	0.1318	No
80	TGM2	TGM2 Entrez, Source	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	9694	-0.049	0.1195	No
81	E2F1	E2F1 Entrez, Source	E2F transcription factor 1	9789	-0.050	0.1171	No
82	HPRT1	HPRT1 Entrez, Source	hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)	9884	-0.052	0.1149	No
83	PDLIM4	PDLIM4 Entrez, Source	PDZ and LIM domain 4	10146	-0.056	0.1004	No
84	PTGS2	PTGS2 Entrez, Source	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	10192	-0.057	0.1023	No
85	TUBB	TUBB Entrez, Source	tubulin, beta	10340	-0.059	0.0968	No
86	HGF	HGF Entrez, Source	hepatocyte growth factor (hepapoietin A; scatter factor)	10486	-0.062	0.0916	No
87	PLAU	PLAU Entrez, Source	plasminogen activator, urokinase	10548	-0.063	0.0929	No
88	VEGF	VEGF Entrez, Source	vascular endothelial growth factor	10686	-0.066	0.0888	No
89	CYP27B1	CYP27B1 Entrez, Source	cytochrome P450, family 27, subfamily B, polypeptide 1	10795	-0.068	0.0870	No
90	RPL15	RPL15 Entrez, Source	ribosomal protein L15	10874	-0.070	0.0877	No
91	NOL5A	NOL5A Entrez, Source	nucleolar protein 5A (56kDa with KKE/D repeat)	11821	-0.096	0.0253	No
92	AMD1	AMD1 Entrez, Source	adenosylmethionine decarboxylase 1	12195	-0.111	0.0076	No
93	GJB2	GJB2 Entrez, Source	gap junction protein, beta 2, 26kDa (connexin 26)	12323	-0.117	0.0090	No
94	FKBP4	FKBP4 Entrez, Source	FK506 binding protein 4, 59kDa	12376	-0.120	0.0163	No
95	SOX9	SOX9 Entrez, Source	SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)	12395	-0.121	0.0263	No
96	MET	MET Entrez, Source	met proto-oncogene (hepatocyte growth factor receptor)	12396	-0.121	0.0377	No
97	PPAT	PPAT Entrez, Source	phosphoribosyl pyrophosphate amidotransferase	12816	-0.154	0.0205	No
98	CA2	CA2 Entrez, Source	carbonic anhydrase II	13081	-0.204	0.0197	No