Details for gene set NETPATH_IL_1_PATHWAY

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in class	double_gel_8d
GeneSet	NETPATH_IL_1_PATHWAY_UP
Enrichment Score (ES)	0.5428702
Normalized Enrichment Score (NES)	1.9559095
Nominal p-value	0.0
FDR q-value	0.008621605
FWER p-Value	0.355

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SERPINE1	SERPINE1 Entrez, Source	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	12	0.803	0.0725	Yes
2	LDHB	LDHB Entrez, Source	lactate dehydrogenase B	61	0.555	0.1197	Yes
3	CCL2	CCL2 Entrez, Source	chemokine (C-C motif) ligand 2	76	0.477	0.1622	Yes
4	LOX	LOX Entrez, Source	lysyl oxidase	82	0.465	0.2044	Yes
5	TNFAIP6	TNFAIP6 Entrez, Source	tumor necrosis factor, alpha-induced protein 6	117	0.402	0.2387	Yes
6	CXCL2	CXCL2 Entrez, Source	chemokine (C-X-C motif) ligand 2	118	0.402	0.2754	Yes
7	CCL20	CCL20 Entrez, Source	chemokine (C-C motif) ligand 20	160	0.355	0.3047	Yes
8	PRNP	PRNP Entrez, Source	prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)	171	0.348	0.3358	Yes
9	AMPD3	AMPD3 Entrez, Source	adenosine monophosphate deaminase (isoform E)	180	0.337	0.3660	Yes
10	RGS4	RGS4 Entrez, Source	regulator of G-protein signalling 4	219	0.308	0.3913	Yes
11	RGS5	RGS5 Entrez, Source	regulator of G-protein signalling 5	306	0.247	0.4074	Yes
12	PLK2	PLK2 Entrez, Source	polo-like kinase 2 (Drosophila)	414	0.206	0.4182	Yes
13	JUN	JUN Entrez, Source	jun oncogene	458	0.194	0.4326	Yes
14	CSF3	CSF3 Entrez, Source	colony stimulating factor 3 (granulocyte)	685	0.152	0.4295	Yes
15	HBEGF	HBEGF Entrez, Source	heparin-binding EGF-like growth factor	717	0.149	0.4408	Yes
16	RHOB	RHOB Entrez, Source	ras homolog gene family, member B	785	0.141	0.4486	Yes
17	GUCY1B3	GUCY1B3 Entrez, Source	guanylate cyclase 1, soluble, beta 3	801	0.140	0.4602	Yes
18	TFPI	TFPI Entrez, Source	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	825	0.137	0.4710	Yes
19	STK39	STK39 Entrez, Source	serine threonine kinase 39 (STE20/SPS1 homolog, yeast)	864	0.133	0.4803	Yes
20	NFKBIA	NFKBIA Entrez, Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	888	0.130	0.4904	Yes
21	IL1B	IL1B Entrez, Source	interleukin 1, beta	1014	0.121	0.4920	Yes
22	LIF	LIF Entrez, Source	leukemia inhibitory factor (cholinergic differentiation factor)	1037	0.118	0.5012	Yes
23	ANXA3	ANXA3 Entrez, Source	annexin A3	1062	0.117	0.5100	Yes
24	CCL7	CCL7 Entrez, Source	chemokine (C-C motif) ligand 7	1159	0.111	0.5130	Yes
25	PRG1	PRG1 Entrez, Source	proteoglycan 1, secretory granule	1285	0.105	0.5131	Yes
26	MMP14	MMP14 Entrez, Source	matrix metallopeptidase 14 (membrane-inserted)	1312	0.104	0.5206	Yes
27	HNMT	HNMT Entrez, Source	histamine N-methyltransferase	1378	0.100	0.5248	Yes
28	GJB1	GJB1 Entrez, Source	gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)	1380	0.100	0.5338	Yes
29	CXCL1	CXCL1 Entrez, Source	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	1541	0.092	0.5302	Yes
30	ZFP36	ZFP36 Entrez, Source	zinc finger protein 36, C3H type, homolog (mouse)	1543	0.092	0.5385	Yes
31	HMGCL	HMGCL Entrez, Source	3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)	1594	0.089	0.5429	Yes
32	PTTG1	PTTG1 Entrez, Source	pituitary tumor-transforming 1	1734	0.083	0.5400	No
33	CXCL5	CXCL5 Entrez, Source	chemokine (C-X-C motif) ligand 5	1832	0.079	0.5399	No
34	IFNG	IFNG Entrez, Source	interferon, gamma	2940	0.050	0.4608	No
35	NR4A3	NR4A3 Entrez, Source	nuclear receptor subfamily 4, group A, member 3	2974	0.049	0.4628	No
36	DCN	DCN Entrez, Source	decorin	3029	0.048	0.4631	No
37	CDK10	CDK10 Entrez, Source	cyclin-dependent kinase (CDC2-like) 10	3149	0.045	0.4583	No
38	APP	APP Entrez, Source	amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)	3298	0.043	0.4510	No
39	CSF2	CSF2 Entrez, Source	colony stimulating factor 2 (granulocyte-macrophage)	3305	0.042	0.4544	No
40	PRKCD	PRKCD Entrez, Source	protein kinase C, delta	3396	0.041	0.4513	No
41	CCL4	CCL4 Entrez, Source	chemokine (C-C motif) ligand 4	3468	0.039	0.4495	No
42	SERPINB3	SERPINB3 Entrez, Source	serpin peptidase inhibitor, clade B (ovalbumin), member 3	3724	0.035	0.4334	No
43	MMP3	MMP3 Entrez, Source	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	3764	0.034	0.4336	No
44	TNFRSF11B	TNFRSF11B Entrez, Source	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	3828	0.033	0.4319	No
45	GNB5	GNB5 Entrez, Source	guanine nucleotide binding protein (G protein), beta 5	4018	0.030	0.4203	No
46	CCL11	CCL11 Entrez, Source	chemokine (C-C motif) ligand 11	4022	0.030	0.4228	No
47	MMP10	MMP10 Entrez, Source	matrix metallopeptidase 10 (stromelysin 2)	4140	0.028	0.4166	No
48	DUSP6	DUSP6 Entrez, Source	dual specificity phosphatase 6	4288	0.026	0.4078	No
49	INHBA	INHBA Entrez, Source	inhibin, beta A (activin A, activin AB alpha polypeptide)	4596	0.021	0.3865	No
50	PTGES	PTGES Entrez, Source	prostaglandin E synthase	4675	0.020	0.3825	No
51	GAPDH	GAPDH Entrez, Source	glyceraldehyde-3-phosphate dehydrogenase	4797	0.018	0.3750	No
52	AK3	AK3 Entrez, Source	adenylate kinase 3	4820	0.018	0.3750	No
53	LCN2	LCN2 Entrez, Source	lipocalin 2 (oncogene 24p3)	4934	0.016	0.3679	No
54	ARSA	ARSA Entrez, Source	arylsulfatase A	4941	0.016	0.3689	No
55	IL6	IL6 Entrez, Source	interleukin 6 (interferon, beta 2)	4953	0.016	0.3695	No
56	MAPK10	MAPK10 Entrez, Source	mitogen-activated protein kinase 10	5148	0.013	0.3561	No
57	IL1A	IL1A Entrez, Source	interleukin 1, alpha	5162	0.013	0.3563	No
58	ID1	ID1 Entrez, Source	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	5296	0.011	0.3473	No
59	MMP12	MMP12 Entrez, Source	matrix metallopeptidase 12 (macrophage elastase)	5434	0.009	0.3378	No
60	PIP5K1A	PIP5K1A Entrez, Source	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	5528	0.008	0.3315	No
61	BMP1	BMP1 Entrez, Source	bone morphogenetic protein 1	5892	0.004	0.3043	No
62	RELA	RELA Entrez, Source	v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)	6260	-0.001	0.2767	No
63	LYPD3	LYPD3 Entrez, Source	LY6/PLAUR domain containing 3	6537	-0.005	0.2563	No
64	UBD	UBD Entrez, Source	ubiquitin D	6622	-0.006	0.2505	No
65	SMAD1	SMAD1 Entrez, Source	SMAD, mothers against DPP homolog 1 (Drosophila)	6658	-0.007	0.2485	No
66	SEPP1	SEPP1 Entrez, Source	selenoprotein P, plasma, 1	6950	-0.010	0.2274	No
67	SHC1	SHC1 Entrez, Source	SHC (Src homology 2 domain containing) transforming protein 1	7269	-0.014	0.2047	No
68	DNMT1	DNMT1 Entrez, Source	DNA (cytosine-5-)-methyltransferase 1	7279	-0.014	0.2053	No
69	ACPP	ACPP Entrez, Source	acid phosphatase, prostate	7380	-0.015	0.1991	No
70	GRAP2	GRAP2 Entrez, Source	GRB2-related adaptor protein 2	7576	-0.018	0.1860	No
71	MYC	MYC Entrez, Source	v-myc myelocytomatosis viral oncogene homolog (avian)	7715	-0.020	0.1773	No
72	TMLHE	TMLHE Entrez, Source	trimethyllysine hydroxylase, epsilon	7760	-0.020	0.1759	No
73	SOD3	SOD3 Entrez, Source	superoxide dismutase 3, extracellular	8030	-0.024	0.1577	No
74	FOSL1	FOSL1 Entrez, Source	FOS-like antigen 1	8279	-0.028	0.1415	No
75	SERPINB2	SERPINB2 Entrez, Source	serpin peptidase inhibitor, clade B (ovalbumin), member 2	8340	-0.028	0.1396	No
76	BIRC3	BIRC3 Entrez, Source	baculoviral IAP repeat-containing 3	8408	-0.029	0.1372	No
77	HSD11B1	HSD11B1 Entrez, Source	hydroxysteroid (11-beta) dehydrogenase 1	8552	-0.031	0.1293	No
78	HSP90AB1	HSP90AB1 Entrez, Source	heat shock protein 90kDa alpha (cytosolic), class B member 1	8666	-0.033	0.1238	No
79	C3	C3 Entrez, Source	complement component 3	8749	-0.034	0.1207	No
80	WARS	WARS Entrez, Source	tryptophanyl-tRNA synthetase	8852	-0.035	0.1162	No
81	GSTA3	GSTA3 Entrez, Source	glutathione S-transferase A3	9247	-0.041	0.0902	No
82	NFKB1	NFKB1 Entrez, Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)	9252	-0.041	0.0937	No
83	AK2	AK2 Entrez, Source	adenylate kinase 2	9770	-0.050	0.0591	No
84	CHI3L1	CHI3L1 Entrez, Source	chitinase 3-like 1 (cartilage glycoprotein-39)	9869	-0.051	0.0564	No
85	HPRT1	HPRT1 Entrez, Source	hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)	9884	-0.052	0.0601	No
86	C1R	C1R Entrez, Source	complement component 1, r subcomponent	10107	-0.055	0.0484	No
87	PTGS2	PTGS2 Entrez, Source	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	10192	-0.057	0.0472	No
88	PDE4D	PDE4D Entrez, Source	phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)	10269	-0.058	0.0467	No
89	PBEF1	PBEF1 Entrez, Source	pre-B-cell colony enhancing factor 1	10279	-0.058	0.0514	No
90	PRKCZ	PRKCZ Entrez, Source	protein kinase C, zeta	10325	-0.059	0.0534	No
91	ARNT	ARNT Entrez, Source	aryl hydrocarbon receptor nuclear translocator	10332	-0.059	0.0583	No
92	RPS21	RPS21 Entrez, Source	ribosomal protein S21	10407	-0.060	0.0582	No
93	GTF2F1	GTF2F1 Entrez, Source	general transcription factor IIF, polypeptide 1, 74kDa	10529	-0.063	0.0548	No
94	GLUL	GLUL Entrez, Source	glutamate-ammonia ligase (glutamine synthetase)	10574	-0.064	0.0573	No
95	TXNRD1	TXNRD1 Entrez, Source	thioredoxin reductase 1	10870	-0.070	0.0415	No
96	PLK1	PLK1 Entrez, Source	polo-like kinase 1 (Drosophila)	10899	-0.071	0.0458	No
97	RUNX1	RUNX1 Entrez, Source	runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)	11134	-0.077	0.0351	No
98	CFB	CFB Entrez, Source	complement factor B	11731	-0.093	-0.0014	No
99	GARS	GARS Entrez, Source	glycyl-tRNA synthetase	11841	-0.097	-0.0007	No
100	ST3GAL4	ST3GAL4 Entrez, Source	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	12158	-0.110	-0.0146	No
101	PTPN21	PTPN21 Entrez, Source	protein tyrosine phosphatase, non-receptor type 21	12166	-0.110	-0.0050	No
102	AMD1	AMD1 Entrez, Source	adenosylmethionine decarboxylase 1	12195	-0.111	0.0030	No
103	CS	CS Entrez, Source	citrate synthase	12219	-0.112	0.0116	No
104	LCP1	LCP1 Entrez, Source	lymphocyte cytosolic protein 1 (L-plastin)	12229	-0.113	0.0212	No
105	IMPDH2	IMPDH2 Entrez, Source	IMP (inosine monophosphate) dehydrogenase 2	12451	-0.124	0.0158	No
106	SOD2	SOD2 Entrez, Source	superoxide dismutase 2, mitochondrial	12736	-0.145	0.0076	No
107	ICAM1	ICAM1 Entrez, Source	intercellular adhesion molecule 1 (CD54), human rhinovirus receptor	12996	-0.183	0.0048	No
108	SULT4A1	SULT4A1 Entrez, Source	sulfotransferase family 4A, member 1	13166	-0.233	0.0133	No