Details for gene set NETPATH_IL_4_PATHWAY

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in class	double_gel_8d
GeneSet	NETPATH_IL_4_PATHWAY_UP
Enrichment Score (ES)	0.49005648
Normalized Enrichment Score (NES)	1.8252337
Nominal p-value	0.0
FDR q-value	0.028663928
FWER p-Value	0.93

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ANXA1	ANXA1 Entrez, Source	annexin A1	10	0.815	0.0483	Yes
2	CYP1A1	CYP1A1 Entrez, Source	cytochrome P450, family 1, subfamily A, polypeptide 1	18	0.708	0.0903	Yes
3	TIMP2	TIMP2 Entrez, Source	TIMP metallopeptidase inhibitor 2	35	0.642	0.1277	Yes
4	RGS2	RGS2 Entrez, Source	regulator of G-protein signalling 2, 24kDa	42	0.616	0.1642	Yes
5	MAF	MAF Entrez, Source	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	73	0.484	0.1911	Yes
6	CCL2	CCL2 Entrez, Source	chemokine (C-C motif) ligand 2	76	0.477	0.2196	Yes
7	LOX	LOX Entrez, Source	lysyl oxidase	82	0.465	0.2472	Yes
8	BMP2	BMP2 Entrez, Source	bone morphogenetic protein 2	91	0.451	0.2737	Yes
9	EGR2	EGR2 Entrez, Source	early growth response 2 (Krox-20 homolog, Drosophila)	130	0.390	0.2943	Yes
10	F13A1	F13A1 Entrez, Source	coagulation factor XIII, A1 polypeptide	135	0.379	0.3167	Yes
11	FOS	FOS Entrez, Source	v-fos FBJ murine osteosarcoma viral oncogene homolog	142	0.371	0.3385	Yes
12	CITED2	CITED2 Entrez, Source	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	145	0.367	0.3604	Yes
13	SLC22A4	SLC22A4 Entrez, Source	solute carrier family 22 (organic cation transporter), member 4	182	0.335	0.3778	Yes
14	JAG1	JAG1 Entrez, Source	jagged 1 (Alagille syndrome)	323	0.239	0.3816	Yes
15	FKBP5	FKBP5 Entrez, Source	FK506 binding protein 5	335	0.235	0.3949	Yes
16	TMOD1	TMOD1 Entrez, Source	tropomodulin 1	370	0.220	0.4055	Yes
17	CPT2	CPT2 Entrez, Source	carnitine palmitoyltransferase II	399	0.209	0.4160	Yes
18	TIMP3	TIMP3 Entrez, Source	TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory)	406	0.208	0.4280	Yes
19	CYP2E1	CYP2E1 Entrez, Source	cytochrome P450, family 2, subfamily E, polypeptide 1	412	0.206	0.4400	Yes
20	F3	F3 Entrez, Source	coagulation factor III (thromboplastin, tissue factor)	418	0.205	0.4520	Yes
21	ABCD3	ABCD3 Entrez, Source	ATP-binding cassette, sub-family D (ALD), member 3	451	0.195	0.4613	Yes
22	JUN	JUN Entrez, Source	jun oncogene	458	0.194	0.4725	Yes
23	FBN1	FBN1 Entrez, Source	fibrillin 1	483	0.185	0.4818	Yes
24	GCNT1	GCNT1 Entrez, Source	glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase)	800	0.140	0.4663	Yes
25	GUCY1B3	GUCY1B3 Entrez, Source	guanylate cyclase 1, soluble, beta 3	801	0.140	0.4746	Yes
26	TFPI	TFPI Entrez, Source	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	825	0.137	0.4811	Yes
27	HS3ST1	HS3ST1 Entrez, Source	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	830	0.136	0.4890	Yes
28	KLF4	KLF4 Entrez, Source	Kruppel-like factor 4 (gut)	1086	0.116	0.4766	Yes
29	RASA2	RASA2 Entrez, Source	RAS p21 protein activator 2	1216	0.109	0.4734	Yes
30	ACTN1	ACTN1 Entrez, Source	actinin, alpha 1	1268	0.106	0.4759	Yes
31	ARG1	ARG1 Entrez, Source	arginase, liver	1316	0.103	0.4785	Yes
32	IL13RA2	IL13RA2 Entrez, Source	interleukin 13 receptor, alpha 2	1324	0.103	0.4842	Yes
33	IL10	IL10 Entrez, Source	interleukin 10	1329	0.102	0.4901	Yes
34	SULF1	SULF1 Entrez, Source	sulfatase 1	1470	0.095	0.4852	No
35	PDZK1IP1	PDZK1IP1 Entrez, Source	PDZK1 interacting protein 1	1523	0.093	0.4869	No
36	SLC38A1	SLC38A1 Entrez, Source	solute carrier family 38, member 1	1690	0.085	0.4794	No
37	PTGER2	PTGER2 Entrez, Source	prostaglandin E receptor 2 (subtype EP2), 53kDa	1691	0.085	0.4845	No
38	CEBPB	CEBPB Entrez, Source	CCAAT/enhancer binding protein (C/EBP), beta	1774	0.082	0.4832	No
39	BMP4	BMP4 Entrez, Source	bone morphogenetic protein 4	1840	0.078	0.4830	No
40	RBMS1	RBMS1 Entrez, Source	RNA binding motif, single stranded interacting protein 1	1934	0.075	0.4805	No
41	GZMB	GZMB Entrez, Source	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	2045	0.071	0.4764	No
42	SCGB3A1	SCGB3A1 Entrez, Source	secretoglobin, family 3A, member 1	2064	0.071	0.4793	No
43	SAMSN1	SAMSN1 Entrez, Source	SAM domain, SH3 domain and nuclear localisation signals, 1	2103	0.070	0.4806	No
44	ITGAM	ITGAM Entrez, Source	integrin, alpha M (complement component 3 receptor 3 subunit)	2172	0.068	0.4796	No
45	ID3	ID3 Entrez, Source	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	2181	0.068	0.4831	No
46	ATXN1	ATXN1 Entrez, Source	ataxin 1	2254	0.066	0.4815	No
47	BCL2	BCL2 Entrez, Source	B-cell CLL/lymphoma 2	2324	0.064	0.4802	No
48	PAWR	PAWR Entrez, Source	PRKC, apoptosis, WT1, regulator	2421	0.061	0.4766	No
49	GNAI1	GNAI1 Entrez, Source	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	2424	0.061	0.4801	No
50	AGC1	AGC1 Entrez, Source	aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122)	2474	0.060	0.4801	No
51	PSCD1	PSCD1 Entrez, Source	pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1)	2579	0.058	0.4757	No
52	CXCR4	CXCR4 Entrez, Source	chemokine (C-X-C motif) receptor 4	2597	0.058	0.4778	No
53	FN1	FN1 Entrez, Source	fibronectin 1	2637	0.057	0.4783	No
54	TLR4	TLR4 Entrez, Source	toll-like receptor 4	2800	0.053	0.4692	No
55	IFNG	IFNG Entrez, Source	interferon, gamma	2940	0.050	0.4617	No
56	UPP1	UPP1 Entrez, Source	uridine phosphorylase 1	3489	0.039	0.4225	No
57	IL13	IL13 Entrez, Source	interleukin 13	3501	0.039	0.4240	No
58	UBL3	UBL3 Entrez, Source	ubiquitin-like 3	3509	0.038	0.4258	No
59	CDC25A	CDC25A Entrez, Source	cell division cycle 25A	3568	0.037	0.4236	No
60	SERPINB3	SERPINB3 Entrez, Source	serpin peptidase inhibitor, clade B (ovalbumin), member 3	3724	0.035	0.4140	No
61	SPINT2	SPINT2 Entrez, Source	serine peptidase inhibitor, Kunitz type, 2	3725	0.035	0.4161	No
62	MAL	MAL Entrez, Source	mal, T-cell differentiation protein	3748	0.034	0.4165	No
63	MAOA	MAOA Entrez, Source	monoamine oxidase A	3833	0.033	0.4121	No
64	CTSL	CTSL Entrez, Source	cathepsin L	3892	0.032	0.4096	No
65	ST8SIA1	ST8SIA1 Entrez, Source	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	3901	0.032	0.4109	No
66	DUSP6	DUSP6 Entrez, Source	dual specificity phosphatase 6	4288	0.026	0.3832	No
67	HPCAL1	HPCAL1 Entrez, Source	hippocalcin-like 1	4353	0.025	0.3799	No
68	ALOX15	ALOX15 Entrez, Source	arachidonate 15-lipoxygenase	4419	0.023	0.3763	No
69	IL2RB	IL2RB Entrez, Source	interleukin 2 receptor, beta	4429	0.023	0.3771	No
70	HSPA8	HSPA8 Entrez, Source	heat shock 70kDa protein 8	4537	0.022	0.3703	No
71	CASP3	CASP3 Entrez, Source	caspase 3, apoptosis-related cysteine peptidase	4567	0.022	0.3694	No
72	INHBA	INHBA Entrez, Source	inhibin, beta A (activin A, activin AB alpha polypeptide)	4596	0.021	0.3685	No
73	IL6	IL6 Entrez, Source	interleukin 6 (interferon, beta 2)	4953	0.016	0.3425	No
74	SOCS3	SOCS3 Entrez, Source	suppressor of cytokine signaling 3	5260	0.012	0.3200	No
75	IL10RA	IL10RA Entrez, Source	interleukin 10 receptor, alpha	6007	0.002	0.2637	No
76	CART1	CART1 Entrez, Source	cartilage paired-class homeoprotein 1	6181	-0.000	0.2506	No
77	STK17B	STK17B Entrez, Source	serine/threonine kinase 17b (apoptosis-inducing)	6193	-0.000	0.2498	No
78	ELL2	ELL2 Entrez, Source	elongation factor, RNA polymerase II, 2	6213	-0.001	0.2484	No
79	RELA	RELA Entrez, Source	v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)	6260	-0.001	0.2450	No
80	KCNK3	KCNK3 Entrez, Source	potassium channel, subfamily K, member 3	6369	-0.003	0.2370	No
81	SATB1	SATB1 Entrez, Source	special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's)	6392	-0.003	0.2355	No
82	GAS6	GAS6 Entrez, Source	growth arrest-specific 6	6432	-0.004	0.2328	No
83	EDNRA	EDNRA Entrez, Source	endothelin receptor type A	6497	-0.004	0.2282	No
84	ALDH1A2	ALDH1A2 Entrez, Source	aldehyde dehydrogenase 1 family, member A2	6558	-0.005	0.2240	No
85	EEF1A2	EEF1A2 Entrez, Source	eukaryotic translation elongation factor 1 alpha 2	6587	-0.006	0.2222	No
86	CREM	CREM Entrez, Source	cAMP responsive element modulator	6850	-0.009	0.2029	No
87	LRRN3	LRRN3 Entrez, Source	leucine rich repeat neuronal 3	6873	-0.009	0.2017	No
88	TFEC	TFEC Entrez, Source	transcription factor EC	7275	-0.014	0.1722	No
89	ST6GAL1	ST6GAL1 Entrez, Source	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	7453	-0.016	0.1598	No
90	CHST10	CHST10 Entrez, Source	carbohydrate sulfotransferase 10	7458	-0.016	0.1605	No
91	NFIL3	NFIL3 Entrez, Source	nuclear factor, interleukin 3 regulated	7648	-0.019	0.1473	No
92	FGL2	FGL2 Entrez, Source	fibrinogen-like 2	7684	-0.019	0.1458	No
93	MYC	MYC Entrez, Source	v-myc myelocytomatosis viral oncogene homolog (avian)	7715	-0.020	0.1447	No
94	AHR	AHR Entrez, Source	aryl hydrocarbon receptor	7804	-0.021	0.1393	No
95	GATA3	GATA3 Entrez, Source	GATA binding protein 3	7809	-0.021	0.1402	No
96	CCL22	CCL22 Entrez, Source	chemokine (C-C motif) ligand 22	7969	-0.023	0.1296	No
97	SLC39A8	SLC39A8 Entrez, Source	solute carrier family 39 (zinc transporter), member 8	8133	-0.026	0.1188	No
98	BCL2L11	BCL2L11 Entrez, Source	BCL2-like 11 (apoptosis facilitator)	8410	-0.030	0.0996	No
99	VDR	VDR Entrez, Source	vitamin D (1,25- dihydroxyvitamin D3) receptor	8460	-0.030	0.0977	No
100	XCL1	XCL1 Entrez, Source	chemokine (C motif) ligand 1	8819	-0.035	0.0727	No
101	SOCS1	SOCS1 Entrez, Source	suppressor of cytokine signaling 1	8877	-0.036	0.0706	No
102	HSPB8	HSPB8 Entrez, Source	heat shock 22kDa protein 8	9051	-0.038	0.0598	No
103	TOP2A	TOP2A Entrez, Source	topoisomerase (DNA) II alpha 170kDa	9154	-0.040	0.0544	No
104	NFKB1	NFKB1 Entrez, Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)	9252	-0.041	0.0496	No
105	IL4R	IL4R Entrez, Source	interleukin 4 receptor	9332	-0.042	0.0461	No
106	SLC11A2	SLC11A2 Entrez, Source	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	9701	-0.049	0.0212	No
107	IGHE	IGHE Entrez, Source	immunoglobulin heavy constant epsilon	9859	-0.051	0.0124	No
108	NKG7	NKG7 Entrez, Source	natural killer cell group 7 sequence	9908	-0.052	0.0118	No
109	GJA5	GJA5 Entrez, Source	gap junction protein, alpha 5, 40kDa (connexin 40)	9982	-0.053	0.0095	No
110	IL1RN	IL1RN Entrez, Source	interleukin 1 receptor antagonist	10196	-0.057	-0.0032	No
111	IGF1	IGF1 Entrez, Source	insulin-like growth factor 1 (somatomedin C)	10373	-0.060	-0.0130	No
112	CSPG2	CSPG2 Entrez, Source	chondroitin sulfate proteoglycan 2 (versican)	10417	-0.061	-0.0126	No
113	CD86	CD86 Entrez, Source	CD86 molecule	10637	-0.065	-0.0252	No
114	S100A9	S100A9 Entrez, Source	S100 calcium binding protein A9	10706	-0.066	-0.0264	No
115	CYP1B1	CYP1B1 Entrez, Source	cytochrome P450, family 1, subfamily B, polypeptide 1	10964	-0.073	-0.0415	No
116	RDX	RDX Entrez, Source	radixin	11042	-0.074	-0.0429	No
117	PMCH	PMCH Entrez, Source	pro-melanin-concentrating hormone	11172	-0.078	-0.0480	No
118	ENPP1	ENPP1 Entrez, Source	ectonucleotide pyrophosphatase/phosphodiesterase 1	11362	-0.083	-0.0573	No
119	CTSC	CTSC Entrez, Source	cathepsin C	11373	-0.083	-0.0531	No
120	DNAJC3	DNAJC3 Entrez, Source	DnaJ (Hsp40) homolog, subfamily C, member 3	11530	-0.087	-0.0596	No
121	CH25H	CH25H Entrez, Source	cholesterol 25-hydroxylase	12118	-0.108	-0.0976	No
122	MCM7	MCM7 Entrez, Source	MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)	12174	-0.110	-0.0951	No
123	IL13RA1	IL13RA1 Entrez, Source	interleukin 13 receptor, alpha 1	12191	-0.111	-0.0896	No
124	CASP2	CASP2 Entrez, Source	caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2)	12210	-0.112	-0.0843	No
125	GATA6	GATA6 Entrez, Source	GATA binding protein 6	12352	-0.119	-0.0878	No
126	MET	MET Entrez, Source	met proto-oncogene (hepatocyte growth factor receptor)	12396	-0.121	-0.0838	No
127	SELE	SELE Entrez, Source	selectin E (endothelial adhesion molecule 1)	12624	-0.136	-0.0928	No
128	POU4F1	POU4F1 Entrez, Source	POU domain, class 4, transcription factor 1	12659	-0.138	-0.0871	No
129	RASGRP1	RASGRP1 Entrez, Source	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	12782	-0.150	-0.0873	No
130	DMD	DMD Entrez, Source	dystrophin (muscular dystrophy, Duchenne and Becker types)	12922	-0.168	-0.0878	No
131	CA2	CA2 Entrez, Source	carbonic anhydrase II	13081	-0.204	-0.0875	No
132	VCAM1	VCAM1 Entrez, Source	vascular cell adhesion molecule 1	13085	-0.205	-0.0754	No
133	MCM6	MCM6 Entrez, Source	MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)	13114	-0.214	-0.0647	No
134	RIPK2	RIPK2 Entrez, Source	receptor-interacting serine-threonine kinase 2	13131	-0.220	-0.0527	No
135	LIFR	LIFR Entrez, Source	leukemia inhibitory factor receptor alpha	13146	-0.224	-0.0402	No
136	EDG1	EDG1 Entrez, Source	endothelial differentiation, sphingolipid G-protein-coupled receptor, 1	13341	-0.915	0.0001	No