Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | NI2_MOUSE_UP |
| Enrichment Score (ES) | 0.6829503 |
| Normalized Enrichment Score (NES) | 1.9827785 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.006738121 |
| FWER p-Value | 0.262 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 15 | 0.737 | 0.2050 | Yes |
| 2 | LOX | LOX Entrez, Source | lysyl oxidase | 82 | 0.465 | 0.3300 | Yes |
| 3 | ANGPTL4 | ANGPTL4 Entrez, Source | angiopoietin-like 4 | 147 | 0.365 | 0.4271 | Yes |
| 4 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 326 | 0.238 | 0.4802 | Yes |
| 5 | KLF6 | KLF6 Entrez, Source | Kruppel-like factor 6 | 364 | 0.225 | 0.5403 | Yes |
| 6 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 559 | 0.171 | 0.5735 | Yes |
| 7 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 888 | 0.130 | 0.5852 | Yes |
| 8 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 1105 | 0.114 | 0.6010 | Yes |
| 9 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 1192 | 0.110 | 0.6252 | Yes |
| 10 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1297 | 0.104 | 0.6466 | Yes |
| 11 | SPHK1 | SPHK1 Entrez, Source | sphingosine kinase 1 | 1303 | 0.104 | 0.6753 | Yes |
| 12 | ZFP36 | ZFP36 Entrez, Source | zinc finger protein 36, C3H type, homolog (mouse) | 1543 | 0.092 | 0.6830 | Yes |
| 13 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 3654 | 0.036 | 0.5345 | No |
| 14 | MAL | MAL Entrez, Source | mal, T-cell differentiation protein | 3748 | 0.034 | 0.5372 | No |
| 15 | LRG1 | LRG1 Entrez, Source | leucine-rich alpha-2-glycoprotein 1 | 3792 | 0.034 | 0.5433 | No |
| 16 | S100A8 | S100A8 Entrez, Source | S100 calcium binding protein A8 | 4260 | 0.026 | 0.5155 | No |
| 17 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 4307 | 0.025 | 0.5191 | No |
| 18 | PTGES | PTGES Entrez, Source | prostaglandin E synthase | 4675 | 0.020 | 0.4972 | No |
| 19 | LCN2 | LCN2 Entrez, Source | lipocalin 2 (oncogene 24p3) | 4934 | 0.016 | 0.4823 | No |
| 20 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 5926 | 0.003 | 0.4087 | No |
| 21 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 6410 | -0.003 | 0.3733 | No |
| 22 | CSTB | CSTB Entrez, Source | cystatin B (stefin B) | 7027 | -0.011 | 0.3301 | No |
| 23 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 7409 | -0.015 | 0.3059 | No |
| 24 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 7715 | -0.020 | 0.2884 | No |
| 25 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 7976 | -0.023 | 0.2753 | No |
| 26 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 8687 | -0.033 | 0.2313 | No |
| 27 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 10672 | -0.066 | 0.1007 | No |
| 28 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 10870 | -0.070 | 0.1055 | No |
| 29 | RBM3 | RBM3 Entrez, Source | RNA binding motif (RNP1, RRM) protein 3 | 12503 | -0.128 | 0.0187 | No |
| 30 | SERPIND1 | SERPIND1 Entrez, Source | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 12846 | -0.158 | 0.0373 | No |
