Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_72h
GeneSetNUCLEAR_LUMEN
Enrichment Score (ES)-0.43962583
Normalized Enrichment Score (NES)-1.8511411
Nominal p-value0.0
FDR q-value0.100685805
FWER p-Value0.74
Table: GSEA Results Summary



Fig 1: Enrichment plot: NUCLEAR_LUMEN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NOL3NOL3
Entrez,  Source
nucleolar protein 3 (apoptosis repressor with CARD domain)3250.238-0.0021No
2DNAJB9DNAJB9
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 94370.1990.0082No
3GCM1GCM1
Entrez,  Source
glial cells missing homolog 1 (Drosophila)6230.1620.0095No
4LMO4LMO4
Entrez,  Source
LIM domain only 48270.1360.0070No
5PITX2PITX2
Entrez,  Source
paired-like homeodomain transcription factor 28500.1340.0180No
6PPARGC1APPARGC1A
Entrez,  Source
peroxisome proliferative activated receptor, gamma, coactivator 1, alpha10680.1160.0126No
7KLHL7KLHL7
Entrez,  Source
kelch-like 7 (Drosophila)11480.1120.0172No
8BNIP3BNIP3
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 311770.1110.0255No
9EPAS1EPAS1
Entrez,  Source
endothelial PAS domain protein 113450.1020.0225No
10HDAC7AHDAC7A
Entrez,  Source
histone deacetylase 7A15980.0890.0118No
11PTF1APTF1A
Entrez,  Source
pancreas specific transcription factor, 1a20080.073-0.0123No
12MEN1MEN1
Entrez,  Source
multiple endocrine neoplasia I20620.071-0.0096No
13ATXN1ATXN1
Entrez,  Source
ataxin 122540.066-0.0179No
14CDK9CDK9
Entrez,  Source
cyclin-dependent kinase 9 (CDC2-related kinase)29150.051-0.0632No
15CIB1CIB1
Entrez,  Source
calcium and integrin binding 1 (calmyrin)32060.045-0.0810No
16HCLS1HCLS1
Entrez,  Source
hematopoietic cell-specific Lyn substrate 135870.037-0.1063No
17PPP1R9BPPP1R9B
Entrez,  Source
protein phosphatase 1, regulatory subunit 9B, spinophilin37260.035-0.1135No
18REXO4REXO4
Entrez,  Source
REX4, RNA exonuclease 4 homolog (S. cerevisiae)40670.029-0.1365No
19SC65SC65
Entrez,  Source
-40760.029-0.1344No
20KPNA2KPNA2
Entrez,  Source
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)41090.029-0.1341No
21NUP98NUP98
Entrez,  Source
nucleoporin 98kDa42170.027-0.1397No
22TAF9TAF9
Entrez,  Source
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa43220.025-0.1452No
23NAP1L2NAP1L2
Entrez,  Source
nucleosome assembly protein 1-like 243540.025-0.1452No
24PPARGC1BPPARGC1B
Entrez,  Source
peroxisome proliferative activated receptor, gamma, coactivator 1, beta43720.024-0.1442No
25NKX2-5NKX2-5
Entrez,  Source
NK2 transcription factor related, locus 5 (Drosophila)44630.023-0.1489No
26HTATIPHTATIP
Entrez,  Source
HIV-1 Tat interacting protein, 60kDa46330.021-0.1598No
27TBPTBP
Entrez,  Source
TATA box binding protein46900.020-0.1621No
28ACTBACTB
Entrez,  Source
actin, beta47140.019-0.1620No
29ASNA1ASNA1
Entrez,  Source
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)47550.019-0.1633No
30HIF1AHIF1A
Entrez,  Source
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)48920.017-0.1720No
31MCRS1MCRS1
Entrez,  Source
microspherule protein 149510.016-0.1749No
32SLU7SLU7
Entrez,  Source
-49760.016-0.1753No
33NARFNARF
Entrez,  Source
nuclear prelamin A recognition factor51270.014-0.1854No
34NCR1NCR1
Entrez,  Source
natural cytotoxicity triggering receptor 151350.013-0.1846No
35CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)51390.013-0.1836No
36GTF3C2GTF3C2
Entrez,  Source
general transcription factor IIIC, polypeptide 2, beta 110kDa51780.013-0.1852No
37NCOA6NCOA6
Entrez,  Source
nuclear receptor coactivator 651960.013-0.1853No
38ERCC3ERCC3
Entrez,  Source
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)52840.011-0.1909No
39CHAF1BCHAF1B
Entrez,  Source
chromatin assembly factor 1, subunit B (p60)53770.010-0.1969No
40NF2NF2
Entrez,  Source
neurofibromin 2 (bilateral acoustic neuroma)54660.009-0.2027No
41NFYBNFYB
Entrez,  Source
nuclear transcription factor Y, beta55210.008-0.2061No
42EXOSC9EXOSC9
Entrez,  Source
exosome component 956420.006-0.2146No
43FOXE3FOXE3
Entrez,  Source
forkhead box E357460.005-0.2219No
44NAP1L4NAP1L4
Entrez,  Source
nucleosome assembly protein 1-like 459350.003-0.2359No
45RTCD1RTCD1
Entrez,  Source
RNA terminal phosphate cyclase domain 159930.002-0.2400No
46GIT2GIT2
Entrez,  Source
G protein-coupled receptor kinase interactor 260060.002-0.2407No
47TOP1TOP1
Entrez,  Source
topoisomerase (DNA) I6189-0.000-0.2545No
48ELL2ELL2
Entrez,  Source
elongation factor, RNA polymerase II, 26213-0.001-0.2561No
49RELARELA
Entrez,  Source
v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)6260-0.001-0.2595No
50NFYCNFYC
Entrez,  Source
nuclear transcription factor Y, gamma6397-0.003-0.2695No
51NFYANFYA
Entrez,  Source
nuclear transcription factor Y, alpha6517-0.005-0.2781No
52HMGA1HMGA1
Entrez,  Source
high mobility group AT-hook 16574-0.005-0.2818No
53TAF11TAF11
Entrez,  Source
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa6619-0.006-0.2846No
54TAF6TAF6
Entrez,  Source
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa6684-0.007-0.2888No
55HDAC5HDAC5
Entrez,  Source
histone deacetylase 56756-0.008-0.2935No
56THRAP3THRAP3
Entrez,  Source
thyroid hormone receptor associated protein 36772-0.008-0.2939No
57SMAD4SMAD4
Entrez,  Source
SMAD, mothers against DPP homolog 4 (Drosophila)6788-0.008-0.2942No
58SMARCA2SMARCA2
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 26971-0.010-0.3071No
59OGG1OGG1
Entrez,  Source
8-oxoguanine DNA glycosylase7030-0.011-0.3104No
60CLOCKCLOCK
Entrez,  Source
clock homolog (mouse)7102-0.012-0.3147No
61HDAC3HDAC3
Entrez,  Source
histone deacetylase 37165-0.013-0.3182No
62SYMPKSYMPK
Entrez,  Source
symplekin7266-0.014-0.3245No
63PARP1PARP1
Entrez,  Source
poly (ADP-ribose) polymerase family, member 17272-0.014-0.3236No
64INTS6INTS6
Entrez,  Source
integrator complex subunit 67424-0.016-0.3335No
65DDX47DDX47
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 477436-0.016-0.3329No
66NAP1L1NAP1L1
Entrez,  Source
nucleosome assembly protein 1-like 17512-0.017-0.3370No
67MORF4L2MORF4L2
Entrez,  Source
mortality factor 4 like 27580-0.018-0.3404No
68SUB1SUB1
Entrez,  Source
SUB1 homolog (S. cerevisiae)7922-0.022-0.3641No
69ZNF148ZNF148
Entrez,  Source
zinc finger protein 1487943-0.023-0.3635No
70SAP18SAP18
Entrez,  Source
Sin3A-associated protein, 18kDa7954-0.023-0.3621No
71SMARCB1SMARCB1
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 17987-0.023-0.3623No
72UBE2IUBE2I
Entrez,  Source
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)8006-0.024-0.3614No
73PRM2PRM2
Entrez,  Source
protamine 28050-0.024-0.3624No
74SFRS2SFRS2
Entrez,  Source
splicing factor, arginine/serine-rich 28111-0.025-0.3646No
75DEDDDEDD
Entrez,  Source
death effector domain containing8149-0.026-0.3650No
76HNRPKHNRPK
Entrez,  Source
heterogeneous nuclear ribonucleoprotein K8260-0.027-0.3707No
77LYARLYAR
Entrez,  Source
-8301-0.028-0.3711No
78PHBPHB
Entrez,  Source
prohibitin8324-0.028-0.3701No
79NUDT21NUDT21
Entrez,  Source
nudix (nucleoside diphosphate linked moiety X)-type motif 218696-0.034-0.3951No
80SMARCD2SMARCD2
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 28700-0.034-0.3921No
81SMAD2SMAD2
Entrez,  Source
SMAD, mothers against DPP homolog 2 (Drosophila)8847-0.035-0.3999No
82CPSF3CPSF3
Entrez,  Source
cleavage and polyadenylation specific factor 3, 73kDa8954-0.037-0.4044No
83IKBKAPIKBKAP
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein9104-0.039-0.4120No
84HDAC10HDAC10
Entrez,  Source
histone deacetylase 109127-0.039-0.4100No
85TOP2ATOP2A
Entrez,  Source
topoisomerase (DNA) II alpha 170kDa9154-0.040-0.4082No
86RPL3RPL3
Entrez,  Source
ribosomal protein L39257-0.041-0.4121No
87SMARCD3SMARCD3
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 39321-0.042-0.4129No
88DNMT3ADNMT3A
Entrez,  Source
DNA (cytosine-5-)-methyltransferase 3 alpha9385-0.043-0.4136No
89DKC1DKC1
Entrez,  Source
dyskeratosis congenita 1, dyskerin9386-0.043-0.4095No
90NCLNCL
Entrez,  Source
nucleolin9448-0.044-0.4099No
91PAX8PAX8
Entrez,  Source
paired box gene 89468-0.044-0.4072No
92IMP4IMP4
Entrez,  Source
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)9749-0.049-0.4237No
93SMC3SMC3
Entrez,  Source
structural maintenance of chromosomes 39824-0.051-0.4246No
94PNMA1PNMA1
Entrez,  Source
paraneoplastic antigen MA19848-0.051-0.4215No
95ZBTB16ZBTB16
Entrez,  Source
zinc finger and BTB domain containing 1610088-0.055-0.4344Yes
96RPL11RPL11
Entrez,  Source
ribosomal protein L1110157-0.056-0.4343Yes
97NOC4LNOC4L
Entrez,  Source
nucleolar complex associated 4 homolog (S. cerevisiae)10159-0.056-0.4291Yes
98DDX24DDX24
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 2410166-0.056-0.4242Yes
99GEMIN6GEMIN6
Entrez,  Source
gem (nuclear organelle) associated protein 610170-0.056-0.4191Yes
100RUVBL2RUVBL2
Entrez,  Source
RuvB-like 2 (E. coli)10227-0.057-0.4179Yes
101COILCOIL
Entrez,  Source
coilin10471-0.062-0.4305Yes
102FGF18FGF18
Entrez,  Source
fibroblast growth factor 1810472-0.062-0.4247Yes
103MED4MED4
Entrez,  Source
mediator of RNA polymerase II transcription, subunit 4 homolog (S. cerevisiae)10512-0.062-0.4218Yes
104GTF2F1GTF2F1
Entrez,  Source
general transcription factor IIF, polypeptide 1, 74kDa10529-0.063-0.4170Yes
105ATXN3ATXN3
Entrez,  Source
ataxin 310628-0.065-0.4183Yes
106MPGMPG
Entrez,  Source
N-methylpurine-DNA glycosylase10650-0.065-0.4138Yes
107SMARCA4SMARCA4
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 410677-0.066-0.4095Yes
108RPP38RPP38
Entrez,  Source
ribonuclease P/MRP 38kDa subunit10683-0.066-0.4036Yes
109PPIGPPIG
Entrez,  Source
peptidylprolyl isomerase G (cyclophilin G)10743-0.067-0.4018Yes
110HDAC2HDAC2
Entrez,  Source
histone deacetylase 210765-0.068-0.3970Yes
111DDX56DDX56
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5610784-0.068-0.3919Yes
112GATAD2AGATAD2A
Entrez,  Source
GATA zinc finger domain containing 2A10877-0.070-0.3922Yes
113HDAC6HDAC6
Entrez,  Source
histone deacetylase 610914-0.071-0.3882Yes
114MKI67IPMKI67IP
Entrez,  Source
MKI67 (FHA domain) interacting nucleolar phosphoprotein10951-0.072-0.3841Yes
115CIRH1ACIRH1A
Entrez,  Source
cirrhosis, autosomal recessive 1A (cirhin)11001-0.073-0.3809Yes
116NUFIP1NUFIP1
Entrez,  Source
nuclear fragile X mental retardation protein interacting protein 111003-0.073-0.3741Yes
117NPM1NPM1
Entrez,  Source
nucleophosmin (nucleolar phosphoprotein B23, numatrin)11090-0.075-0.3734Yes
118MYBBP1AMYBBP1A
Entrez,  Source
MYB binding protein (P160) 1a11212-0.079-0.3752Yes
119RBM39RBM39
Entrez,  Source
RNA binding motif protein 3911305-0.082-0.3744Yes
120RPP40RPP40
Entrez,  Source
ribonuclease P 40kDa subunit11316-0.082-0.3674Yes
121GNL3GNL3
Entrez,  Source
guanine nucleotide binding protein-like 3 (nucleolar)11323-0.082-0.3601Yes
122TEP1TEP1
Entrez,  Source
telomerase-associated protein 111364-0.083-0.3553Yes
123TFIP11TFIP11
Entrez,  Source
tuftelin interacting protein 1111393-0.084-0.3495Yes
124PTBP1PTBP1
Entrez,  Source
polypyrimidine tract binding protein 111792-0.095-0.3707Yes
125NOL5ANOL5A
Entrez,  Source
nucleolar protein 5A (56kDa with KKE/D repeat)11821-0.096-0.3637Yes
126RPL35RPL35
Entrez,  Source
ribosomal protein L3511865-0.098-0.3577Yes
127ACTL6AACTL6A
Entrez,  Source
actin-like 6A11873-0.098-0.3489Yes
128TAF2TAF2
Entrez,  Source
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa11894-0.099-0.3411Yes
129SP140SP140
Entrez,  Source
SP140 nuclear body protein11896-0.099-0.3318Yes
130FUSIP1FUSIP1
Entrez,  Source
FUS interacting protein (serine/arginine-rich) 111902-0.099-0.3228Yes
131GTF3C1GTF3C1
Entrez,  Source
general transcription factor IIIC, polypeptide 1, alpha 220kDa11971-0.102-0.3183Yes
132ISG20ISG20
Entrez,  Source
interferon stimulated exonuclease gene 20kDa12100-0.107-0.3179Yes
133SLC29A2SLC29A2
Entrez,  Source
solute carrier family 29 (nucleoside transporters), member 212103-0.107-0.3078Yes
134NCBP1NCBP1
Entrez,  Source
nuclear cap binding protein subunit 1, 80kDa12122-0.108-0.2990Yes
135MCM7MCM7
Entrez,  Source
MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)12174-0.110-0.2924Yes
136CDKN2ACDKN2A
Entrez,  Source
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)12189-0.111-0.2830Yes
137PHF12PHF12
Entrez,  Source
PHD finger protein 1212208-0.112-0.2738Yes
138SPTBN4SPTBN4
Entrez,  Source
spectrin, beta, non-erythrocytic 412231-0.113-0.2648Yes
139XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)12235-0.113-0.2543Yes
140GTF2H4GTF2H4
Entrez,  Source
general transcription factor IIH, polypeptide 4, 52kDa12316-0.117-0.2493Yes
141RUVBL1RUVBL1
Entrez,  Source
RuvB-like 1 (E. coli)12430-0.123-0.2463Yes
142NOLC1NOLC1
Entrez,  Source
nucleolar and coiled-body phosphoprotein 112447-0.123-0.2358Yes
143RPS19RPS19
Entrez,  Source
ribosomal protein S1912470-0.125-0.2257Yes
144UBTFUBTF
Entrez,  Source
upstream binding transcription factor, RNA polymerase I12542-0.131-0.2187Yes
145ARID1BARID1B
Entrez,  Source
AT rich interactive domain 1B (SWI1-like)12572-0.133-0.2083Yes
146NUP54NUP54
Entrez,  Source
nucleoporin 54kDa12635-0.137-0.2001Yes
147POLR3CPOLR3C
Entrez,  Source
polymerase (RNA) III (DNA directed) polypeptide C (62kD)12669-0.139-0.1894Yes
148FMR1FMR1
Entrez,  Source
fragile X mental retardation 112694-0.141-0.1779Yes
149TP53TP53
Entrez,  Source
tumor protein p53 (Li-Fraumeni syndrome)12718-0.143-0.1661Yes
150XRCC6XRCC6
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa)12731-0.144-0.1534Yes
151HES6HES6
Entrez,  Source
hairy and enhancer of split 6 (Drosophila)12756-0.147-0.1413Yes
152DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A12862-0.160-0.1341Yes
153TDGTDG
Entrez,  Source
thymine-DNA glycosylase12879-0.162-0.1200Yes
154MRE11AMRE11A
Entrez,  Source
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)13022-0.190-0.1128Yes
155SDAD1SDAD1
Entrez,  Source
SDA1 domain containing 113043-0.196-0.0958Yes
156NUAK2NUAK2
Entrez,  Source
NUAK family, SNF1-like kinase, 213065-0.201-0.0784Yes
157RB1RB1
Entrez,  Source
retinoblastoma 1 (including osteosarcoma)13067-0.201-0.0595Yes
158NAP1L3NAP1L3
Entrez,  Source
nucleosome assembly protein 1-like 313164-0.231-0.0449Yes
159APTXAPTX
Entrez,  Source
aprataxin13219-0.270-0.0234Yes
160ARNTLARNTL
Entrez,  Source
aryl hydrocarbon receptor nuclear translocator-like13280-0.3450.0047Yes
Table: GSEA details [plain text format]



Fig 2: NUCLEAR_LUMEN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: NUCLEAR_LUMEN: Random ES distribution   
Gene set null distribution of ES for NUCLEAR_LUMEN