Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | NUCLEOLUS |
| Enrichment Score (ES) | -0.48020628 |
| Normalized Enrichment Score (NES) | -1.6136736 |
| Nominal p-value | 0.009090909 |
| FDR q-value | 0.20954025 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 325 | 0.238 | 0.0407 | No |
| 2 | DNAJB9 | DNAJB9 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 9 | 437 | 0.199 | 0.0868 | No |
| 3 | KLHL7 | KLHL7 Entrez, Source | kelch-like 7 (Drosophila) | 1148 | 0.112 | 0.0642 | No |
| 4 | REXO4 | REXO4 Entrez, Source | REX4, RNA exonuclease 4 homolog (S. cerevisiae) | 4067 | 0.029 | -0.1473 | No |
| 5 | SC65 | SC65 Entrez, Source | - | 4076 | 0.029 | -0.1400 | No |
| 6 | ASNA1 | ASNA1 Entrez, Source | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 4755 | 0.019 | -0.1858 | No |
| 7 | NF2 | NF2 Entrez, Source | neurofibromin 2 (bilateral acoustic neuroma) | 5466 | 0.009 | -0.2368 | No |
| 8 | EXOSC9 | EXOSC9 Entrez, Source | exosome component 9 | 5642 | 0.006 | -0.2482 | No |
| 9 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 6189 | -0.000 | -0.2891 | No |
| 10 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 7272 | -0.014 | -0.3667 | No |
| 11 | DDX47 | DDX47 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 | 7436 | -0.016 | -0.3746 | No |
| 12 | MORF4L2 | MORF4L2 Entrez, Source | mortality factor 4 like 2 | 7580 | -0.018 | -0.3805 | No |
| 13 | DEDD | DEDD Entrez, Source | death effector domain containing | 8149 | -0.026 | -0.4162 | No |
| 14 | LYAR | LYAR Entrez, Source | - | 8301 | -0.028 | -0.4199 | No |
| 15 | IKBKAP | IKBKAP Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein | 9104 | -0.039 | -0.4695 | Yes |
| 16 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9154 | -0.040 | -0.4624 | Yes |
| 17 | RPL3 | RPL3 Entrez, Source | ribosomal protein L3 | 9257 | -0.041 | -0.4588 | Yes |
| 18 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 9386 | -0.043 | -0.4566 | Yes |
| 19 | NCL | NCL Entrez, Source | nucleolin | 9448 | -0.044 | -0.4491 | Yes |
| 20 | IMP4 | IMP4 Entrez, Source | IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) | 9749 | -0.049 | -0.4581 | Yes |
| 21 | PNMA1 | PNMA1 Entrez, Source | paraneoplastic antigen MA1 | 9848 | -0.051 | -0.4516 | Yes |
| 22 | RPL11 | RPL11 Entrez, Source | ribosomal protein L11 | 10157 | -0.056 | -0.4594 | Yes |
| 23 | NOC4L | NOC4L Entrez, Source | nucleolar complex associated 4 homolog (S. cerevisiae) | 10159 | -0.056 | -0.4441 | Yes |
| 24 | DDX24 | DDX24 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 | 10166 | -0.056 | -0.4291 | Yes |
| 25 | COIL | COIL Entrez, Source | coilin | 10471 | -0.062 | -0.4351 | Yes |
| 26 | FGF18 | FGF18 Entrez, Source | fibroblast growth factor 18 | 10472 | -0.062 | -0.4183 | Yes |
| 27 | RPP38 | RPP38 Entrez, Source | ribonuclease P/MRP 38kDa subunit | 10683 | -0.066 | -0.4160 | Yes |
| 28 | DDX56 | DDX56 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 | 10784 | -0.068 | -0.4049 | Yes |
| 29 | MKI67IP | MKI67IP Entrez, Source | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 10951 | -0.072 | -0.3976 | Yes |
| 30 | CIRH1A | CIRH1A Entrez, Source | cirrhosis, autosomal recessive 1A (cirhin) | 11001 | -0.073 | -0.3812 | Yes |
| 31 | NUFIP1 | NUFIP1 Entrez, Source | nuclear fragile X mental retardation protein interacting protein 1 | 11003 | -0.073 | -0.3612 | Yes |
| 32 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 11090 | -0.075 | -0.3470 | Yes |
| 33 | MYBBP1A | MYBBP1A Entrez, Source | MYB binding protein (P160) 1a | 11212 | -0.079 | -0.3345 | Yes |
| 34 | RPP40 | RPP40 Entrez, Source | ribonuclease P 40kDa subunit | 11316 | -0.082 | -0.3198 | Yes |
| 35 | GNL3 | GNL3 Entrez, Source | guanine nucleotide binding protein-like 3 (nucleolar) | 11323 | -0.082 | -0.2978 | Yes |
| 36 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 11792 | -0.095 | -0.3069 | Yes |
| 37 | NOL5A | NOL5A Entrez, Source | nucleolar protein 5A (56kDa with KKE/D repeat) | 11821 | -0.096 | -0.2827 | Yes |
| 38 | RPL35 | RPL35 Entrez, Source | ribosomal protein L35 | 11865 | -0.098 | -0.2590 | Yes |
| 39 | SLC29A2 | SLC29A2 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 2 | 12103 | -0.107 | -0.2474 | Yes |
| 40 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 12189 | -0.111 | -0.2234 | Yes |
| 41 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12447 | -0.123 | -0.2089 | Yes |
| 42 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 12470 | -0.125 | -0.1763 | Yes |
| 43 | UBTF | UBTF Entrez, Source | upstream binding transcription factor, RNA polymerase I | 12542 | -0.131 | -0.1457 | Yes |
| 44 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 12694 | -0.141 | -0.1184 | Yes |
| 45 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 12718 | -0.143 | -0.0810 | Yes |
| 46 | SDAD1 | SDAD1 Entrez, Source | SDA1 domain containing 1 | 13043 | -0.196 | -0.0516 | Yes |
| 47 | APTX | APTX Entrez, Source | aprataxin | 13219 | -0.270 | 0.0093 | Yes |
