Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_8d
GeneSetORGAN_DEVELOPMENT
Enrichment Score (ES)0.41969803
Normalized Enrichment Score (NES)1.7527015
Nominal p-value0.0
FDR q-value0.039755672
FWER p-Value0.999
Table: GSEA Results Summary



Fig 1: Enrichment plot: ORGAN_DEVELOPMENT   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 231.0460.0372Yes
2LAMC2LAMC2
Entrez,  Source
laminin, gamma 2140.7700.0640Yes
3COL5A2COL5A2
Entrez,  Source
collagen, type V, alpha 2280.6680.0869Yes
4CTGFCTGF
Entrez,  Source
connective tissue growth factor320.6600.1103Yes
5EMP1EMP1
Entrez,  Source
epithelial membrane protein 1440.6060.1311Yes
6MGPMGP
Entrez,  Source
matrix Gla protein620.5330.1489Yes
7CCL2CCL2
Entrez,  Source
chemokine (C-C motif) ligand 2760.4770.1650Yes
8BMP2BMP2
Entrez,  Source
bone morphogenetic protein 2910.4510.1800Yes
9PLCE1PLCE1
Entrez,  Source
phospholipase C, epsilon 11140.4080.1929Yes
10PRELPPRELP
Entrez,  Source
proline/arginine-rich end leucine-rich repeat protein1190.4010.2070Yes
11CDH13CDH13
Entrez,  Source
cadherin 13, H-cadherin (heart)1280.3910.2204Yes
12EGR2EGR2
Entrez,  Source
early growth response 2 (Krox-20 homolog, Drosophila)1300.3900.2342Yes
13FSTFST
Entrez,  Source
follistatin1320.3880.2480Yes
14CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 21450.3670.2603Yes
15ANGPTL4ANGPTL4
Entrez,  Source
angiopoietin-like 41470.3650.2732Yes
16LAMC1LAMC1
Entrez,  Source
laminin, gamma 1 (formerly LAMB2)2240.3030.2782Yes
17SPARCSPARC
Entrez,  Source
secreted protein, acidic, cysteine-rich (osteonectin)2340.2970.2882Yes
18TAGLNTAGLN
Entrez,  Source
transgelin2530.2800.2968Yes
19GJB5GJB5
Entrez,  Source
gap junction protein, beta 5 (connexin 31.1)3220.2390.3001Yes
20TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 23670.2230.3047Yes
21USH2AUSH2A
Entrez,  Source
Usher syndrome 2A (autosomal recessive, mild)4250.2020.3076Yes
22STSSTS
Entrez,  Source
steroid sulfatase (microsomal), arylsulfatase C, isozyme S4360.1990.3139Yes
23IGF2IGF2
Entrez,  Source
insulin-like growth factor 2 (somatomedin A)4800.1860.3173Yes
24FBN1FBN1
Entrez,  Source
fibrillin 14830.1850.3238Yes
25SGCESGCE
Entrez,  Source
sarcoglycan, epsilon4840.1850.3304Yes
26IGFBP3IGFBP3
Entrez,  Source
insulin-like growth factor binding protein 35670.1700.3302Yes
27FABP1FABP1
Entrez,  Source
fatty acid binding protein 1, liver6160.1630.3323Yes
28FGF10FGF10
Entrez,  Source
fibroblast growth factor 106320.1600.3369Yes
29SPRY2SPRY2
Entrez,  Source
sprouty homolog 2 (Drosophila)6630.1560.3402Yes
30BTDBTD
Entrez,  Source
biotinidase6700.1550.3453Yes
31ACVRL1ACVRL1
Entrez,  Source
activin A receptor type II-like 16780.1530.3502Yes
32HSD17B3HSD17B3
Entrez,  Source
hydroxysteroid (17-beta) dehydrogenase 36800.1520.3556Yes
33OTX2OTX2
Entrez,  Source
orthodenticle homolog 2 (Drosophila)7080.1500.3589Yes
34HBEGFHBEGF
Entrez,  Source
heparin-binding EGF-like growth factor7170.1490.3636Yes
35PDPNPDPN
Entrez,  Source
podoplanin7240.1480.3684Yes
36PROK2PROK2
Entrez,  Source
prokineticin 27320.1460.3731Yes
37COL1A1COL1A1
Entrez,  Source
collagen, type I, alpha 17380.1460.3779Yes
38RHOBRHOB
Entrez,  Source
ras homolog gene family, member B7850.1410.3794Yes
39PF4PF4
Entrez,  Source
platelet factor 4 (chemokine (C-X-C motif) ligand 4)7980.1400.3835Yes
40IFRD1IFRD1
Entrez,  Source
interferon-related developmental regulator 18410.1350.3851Yes
41FLI1FLI1
Entrez,  Source
Friend leukemia virus integration 18490.1340.3894Yes
42PITX2PITX2
Entrez,  Source
paired-like homeodomain transcription factor 28500.1340.3942Yes
43EIF2B2EIF2B2
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa9240.1270.3931Yes
44IL17FIL17F
Entrez,  Source
interleukin 17F9460.1250.3960Yes
45KLKL
Entrez,  Source
klotho9670.1240.3989Yes
46TWIST1TWIST1
Entrez,  Source
twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) (Drosophila)9780.1230.4026Yes
47DSPPDSPP
Entrez,  Source
dentin sialophosphoprotein10200.1200.4037Yes
48PLOD1PLOD1
Entrez,  Source
procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 110570.1170.4051Yes
49ERBB2ERBB2
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)10720.1160.4082Yes
50SGCGSGCG
Entrez,  Source
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)10850.1160.4114Yes
51KLF4KLF4
Entrez,  Source
Kruppel-like factor 4 (gut)10860.1160.4156Yes
52TMEM176BTMEM176B
Entrez,  Source
transmembrane protein 176B10870.1160.4197Yes
53SPHK1SPHK1
Entrez,  Source
sphingosine kinase 113030.1040.4069No
54IL10IL10
Entrez,  Source
interleukin 1013290.1020.4087No
55APOA5APOA5
Entrez,  Source
apolipoprotein A-V13440.1020.4112No
56ALDH3A2ALDH3A2
Entrez,  Source
aldehyde dehydrogenase 3 family, member A213520.1010.4143No
57COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 413730.1000.4163No
58AGGF1AGGF1
Entrez,  Source
angiogenic factor with G patch and FHA domains 115070.0940.4095No
59MYF6MYF6
Entrez,  Source
myogenic factor 6 (herculin)15360.0920.4106No
60HDAC7AHDAC7A
Entrez,  Source
histone deacetylase 7A15980.0890.4091No
61TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 116740.0860.4064No
62CSF1CSF1
Entrez,  Source
colony stimulating factor 1 (macrophage)16830.0860.4089No
63CHRDCHRD
Entrez,  Source
chordin17330.0830.4081No
64ANXA2ANXA2
Entrez,  Source
annexin A218250.0790.4039No
65BMP4BMP4
Entrez,  Source
bone morphogenetic protein 418400.0780.4057No
66MAPK12MAPK12
Entrez,  Source
mitogen-activated protein kinase 1218450.0780.4082No
67FGF12FGF12
Entrez,  Source
fibroblast growth factor 1219470.0750.4031No
68GHSRGHSR
Entrez,  Source
growth hormone secretagogue receptor19790.0740.4033No
69PLAC1PLAC1
Entrez,  Source
placenta-specific 119840.0740.4057No
70PTF1APTF1A
Entrez,  Source
pancreas specific transcription factor, 1a20080.0730.4065No
71NKX6-1NKX6-1
Entrez,  Source
NK6 transcription factor related, locus 1 (Drosophila)20240.0720.4079No
72PTPRCPTPRC
Entrez,  Source
protein tyrosine phosphatase, receptor type, C20440.0710.4090No
73TGFB1TGFB1
Entrez,  Source
transforming growth factor, beta 1 (Camurati-Engelmann disease)20790.0710.4090No
74NPPBNPPB
Entrez,  Source
natriuretic peptide precursor B20840.0700.4112No
75ALAS2ALAS2
Entrez,  Source
aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia)21000.0700.4125No
76THY1THY1
Entrez,  Source
Thy-1 cell surface antigen21310.0690.4127No
77LHBLHB
Entrez,  Source
luteinizing hormone beta polypeptide22810.0650.4036No
78CD4CD4
Entrez,  Source
CD4 molecule23050.0640.4041No
79CNTN4CNTN4
Entrez,  Source
contactin 423220.0640.4052No
80BTG1BTG1
Entrez,  Source
B-cell translocation gene 1, anti-proliferative23500.0630.4053No
81OSTF1OSTF1
Entrez,  Source
osteoclast stimulating factor 123990.0620.4039No
82DMP1DMP1
Entrez,  Source
dentin matrix acidic phosphoprotein24330.0610.4035No
83COL11A1COL11A1
Entrez,  Source
collagen, type XI, alpha 124720.0600.4028No
84CRABP2CRABP2
Entrez,  Source
cellular retinoic acid binding protein 225660.0580.3977No
85SLIT1SLIT1
Entrez,  Source
slit homolog 1 (Drosophila)25780.0580.3990No
86MYOD1MYOD1
Entrez,  Source
myogenic differentiation 126690.0560.3940No
87MRASMRAS
Entrez,  Source
muscle RAS oncogene homolog27740.0530.3880No
88GAAGAA
Entrez,  Source
glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II)28390.0520.3849No
89LSRLSR
Entrez,  Source
lipolysis stimulated lipoprotein receptor28660.0510.3847No
90SLIT2SLIT2
Entrez,  Source
slit homolog 2 (Drosophila)28850.0510.3852No
91PPT1PPT1
Entrez,  Source
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)29450.0500.3824No
92GHRHRGHRHR
Entrez,  Source
growth hormone releasing hormone receptor29920.0490.3807No
93EREGEREG
Entrez,  Source
epiregulin29990.0490.3819No
94DCNDCN
Entrez,  Source
decorin30290.0480.3814No
95MYH3MYH3
Entrez,  Source
myosin, heavy chain 3, skeletal muscle, embryonic31640.0450.3727No
96SPEGSPEG
Entrez,  Source
SPEG complex locus31710.0450.3739No
97COL18A1COL18A1
Entrez,  Source
collagen, type XVIII, alpha 132490.0440.3695No
98NRP1NRP1
Entrez,  Source
neuropilin 133040.0420.3669No
99TINAGTINAG
Entrez,  Source
tubulointerstitial nephritis antigen34220.0400.3594No
100PTHR1PTHR1
Entrez,  Source
parathyroid hormone receptor 134370.0400.3597No
101HCLS1HCLS1
Entrez,  Source
hematopoietic cell-specific Lyn substrate 135870.0370.3496No
102DFNB31DFNB31
Entrez,  Source
deafness, autosomal recessive 3136710.0360.3445No
103MALMAL
Entrez,  Source
mal, T-cell differentiation protein37480.0340.3399No
104TNFRSF11BTNFRSF11B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)38280.0330.3350No
105TWIST2TWIST2
Entrez,  Source
twist homolog 2 (Drosophila)38290.0330.3362No
106SFTPBSFTPB
Entrez,  Source
surfactant, pulmonary-associated protein B38790.0320.3336No
107ATP2C1ATP2C1
Entrez,  Source
ATPase, Ca++ transporting, type 2C, member 138960.0320.3335No
108SMTNSMTN
Entrez,  Source
smoothelin39240.0310.3325No
109TBX3TBX3
Entrez,  Source
T-box 3 (ulnar mammary syndrome)39430.0310.3323No
110DGCR2DGCR2
Entrez,  Source
DiGeorge syndrome critical region gene 240390.0300.3260No
111GDF11GDF11
Entrez,  Source
growth differentiation factor 1140490.0300.3264No
112EGR3EGR3
Entrez,  Source
early growth response 341010.0290.3235No
113ZIC1ZIC1
Entrez,  Source
Zic family member 1 (odd-paired homolog, Drosophila)41450.0280.3212No
114MATKMATK
Entrez,  Source
megakaryocyte-associated tyrosine kinase42590.0260.3135No
115AESAES
Entrez,  Source
amino-terminal enhancer of split42690.0260.3137No
116VAX2VAX2
Entrez,  Source
ventral anterior homeobox 242780.0260.3140No
117BRAFBRAF
Entrez,  Source
v-raf murine sarcoma viral oncogene homolog B142950.0260.3137No
118ROBO2ROBO2
Entrez,  Source
roundabout, axon guidance receptor, homolog 2 (Drosophila)42990.0250.3144No
119ACVR2AACVR2A
Entrez,  Source
activin A receptor, type IIA43250.0250.3133No
120PITPNM1PITPNM1
Entrez,  Source
phosphatidylinositol transfer protein, membrane-associated 143500.0250.3124No
121FOXG143580.0240.3127No
122COL12A1COL12A1
Entrez,  Source
collagen, type XII, alpha 143630.0240.3133No
123CSRP3CSRP3
Entrez,  Source
cysteine and glycine-rich protein 3 (cardiac LIM protein)43690.0240.3138No
124UBBUBB
Entrez,  Source
ubiquitin B43790.0240.3139No
125CASRCASR
Entrez,  Source
calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism)44610.0230.3085No
126MSX1MSX1
Entrez,  Source
msh homeobox homolog 1 (Drosophila)45360.0220.3036No
127BLNKBLNK
Entrez,  Source
B-cell linker45390.0220.3043No
128PTHLHPTHLH
Entrez,  Source
parathyroid hormone-like hormone45940.0210.3009No
129INHBAINHBA
Entrez,  Source
inhibin, beta A (activin A, activin AB alpha polypeptide)45960.0210.3015No
130SCINSCIN
Entrez,  Source
scinderin46190.0210.3006No
131AHSGAHSG
Entrez,  Source
alpha-2-HS-glycoprotein47330.0190.2926No
132POU1F1POU1F1
Entrez,  Source
POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1)47410.0190.2927No
133TLE2TLE2
Entrez,  Source
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)47680.0190.2914No
134FLOT2FLOT2
Entrez,  Source
flotillin 248690.0170.2844No
135MYH11MYH11
Entrez,  Source
myosin, heavy chain 11, smooth muscle48990.0170.2827No
136CAPN3CAPN3
Entrez,  Source
calpain 3, (p94)49550.0160.2791No
137CHRNA7CHRNA7
Entrez,  Source
cholinergic receptor, nicotinic, alpha 750370.0150.2734No
138CHRNA1CHRNA1
Entrez,  Source
cholinergic receptor, nicotinic, alpha 1 (muscle)50520.0150.2728No
139DLL3DLL3
Entrez,  Source
delta-like 3 (Drosophila)51370.0130.2669No
140JAG2JAG2
Entrez,  Source
jagged 251670.0130.2651No
141NCOA6NCOA6
Entrez,  Source
nuclear receptor coactivator 651960.0130.2634No
142CDC42CDC42
Entrez,  Source
cell division cycle 42 (GTP binding protein, 25kDa)52020.0130.2635No
143GYLTL1BGYLTL1B
Entrez,  Source
glycosyltransferase-like 1B52250.0120.2622No
144HAND2HAND2
Entrez,  Source
heart and neural crest derivatives expressed 252260.0120.2627No
145GHRLGHRL
Entrez,  Source
ghrelin/obestatin preprohormone52310.0120.2628No
146KCNH1KCNH1
Entrez,  Source
potassium voltage-gated channel, subfamily H (eag-related), member 152320.0120.2632No
147FGF16FGF16
Entrez,  Source
fibroblast growth factor 1652450.0120.2627No
148SIRT2SIRT2
Entrez,  Source
sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)52810.0110.2604No
149ERCC3ERCC3
Entrez,  Source
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)52840.0110.2607No
150ATPIF1ATPIF1
Entrez,  Source
ATPase inhibitory factor 153460.0100.2564No
151EYA2EYA2
Entrez,  Source
eyes absent homolog 2 (Drosophila)53810.0100.2541No
152EMDEMD
Entrez,  Source
emerin (Emery-Dreifuss muscular dystrophy)54280.0090.2509No
153EIF2AK3EIF2AK3
Entrez,  Source
eukaryotic translation initiation factor 2-alpha kinase 354370.0090.2506No
154CRXCRX
Entrez,  Source
cone-rod homeobox54390.0090.2509No
155DSPDSP
Entrez,  Source
desmoplakin54520.0090.2503No
156ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle54640.0090.2498No
157MEPEMEPE
Entrez,  Source
matrix, extracellular phosphoglycoprotein with ASARM motif (bone)54730.0090.2495No
158MYH7MYH7
Entrez,  Source
myosin, heavy chain 7, cardiac muscle, beta54750.0090.2497No
159FGF2FGF2
Entrez,  Source
fibroblast growth factor 2 (basic)55270.0080.2461No
160LHX3LHX3
Entrez,  Source
LIM homeobox 355600.0070.2439No
161COL2A1COL2A1
Entrez,  Source
collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital)55690.0070.2435No
162SYKSYK
Entrez,  Source
spleen tyrosine kinase55700.0070.2438No
163CACNB2CACNB2
Entrez,  Source
calcium channel, voltage-dependent, beta 2 subunit55710.0070.2440No
164PHGDHPHGDH
Entrez,  Source
phosphoglycerate dehydrogenase56950.0060.2348No
165SHHSHH
Entrez,  Source
sonic hedgehog homolog (Drosophila)57790.0050.2286No
166CACNA1HCACNA1H
Entrez,  Source
calcium channel, voltage-dependent, alpha 1H subunit58440.0040.2238No
167FGF7FGF7
Entrez,  Source
fibroblast growth factor 7 (keratinocyte growth factor)58750.0040.2216No
168BMP1BMP1
Entrez,  Source
bone morphogenetic protein 158920.0040.2205No
169MEF2DMEF2D
Entrez,  Source
MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D)60250.0020.2105No
170LHX1LHX1
Entrez,  Source
LIM homeobox 161160.0000.2036No
171NNATNNAT
Entrez,  Source
neuronatin61220.0000.2032No
172TNFSF12TNFSF12
Entrez,  Source
tumor necrosis factor (ligand) superfamily, member 1261400.0000.2019No
173NOTCH1NOTCH1
Entrez,  Source
Notch homolog 1, translocation-associated (Drosophila)61410.0000.2019No
174CD3DCD3D
Entrez,  Source
CD3d molecule, delta (CD3-TCR complex)6312-0.0020.1889No
175LAMB3LAMB3
Entrez,  Source
laminin, beta 36323-0.0020.1882No
176PRLPRL
Entrez,  Source
prolactin6356-0.0020.1859No
177CTF1CTF1
Entrez,  Source
cardiotrophin 16357-0.0020.1860No
178NR0B1NR0B1
Entrez,  Source
nuclear receptor subfamily 0, group B, member 16385-0.0030.1840No
179LAMA3LAMA3
Entrez,  Source
laminin, alpha 36404-0.0030.1827No
180PITX3PITX3
Entrez,  Source
paired-like homeodomain transcription factor 36413-0.0030.1822No
181GLI1GLI1
Entrez,  Source
glioma-associated oncogene homolog 1 (zinc finger protein)6483-0.0040.1771No
182COL9A1COL9A1
Entrez,  Source
collagen, type IX, alpha 16489-0.0040.1768No
183CANXCANX
Entrez,  Source
calnexin6492-0.0040.1768No
184SIX3SIX3
Entrez,  Source
sine oculis homeobox homolog 3 (Drosophila)6502-0.0040.1763No
185NOTCH4NOTCH4
Entrez,  Source
Notch homolog 4 (Drosophila)6512-0.0050.1758No
186CALCACALCA
Entrez,  Source
calcitonin/calcitonin-related polypeptide, alpha6521-0.0050.1753No
187RAB3DRAB3D
Entrez,  Source
RAB3D, member RAS oncogene family6624-0.0060.1677No
188RUNX2RUNX2
Entrez,  Source
runt-related transcription factor 26625-0.0060.1679No
189FGD1FGD1
Entrez,  Source
FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia)6676-0.0070.1643No
190EMCNEMCN
Entrez,  Source
endomucin6694-0.0070.1633No
191HDAC5HDAC5
Entrez,  Source
histone deacetylase 56756-0.0080.1589No
192EGFL7EGFL7
Entrez,  Source
EGF-like-domain, multiple 76762-0.0080.1588No
193TCF21TCF21
Entrez,  Source
transcription factor 216846-0.0090.1527No
194PRDX1PRDX1
Entrez,  Source
peroxiredoxin 16870-0.0090.1513No
195PTHPTH
Entrez,  Source
parathyroid hormone6899-0.0090.1494No
196TTNTTN
Entrez,  Source
titin6911-0.0100.1489No
197IL12BIL12B
Entrez,  Source
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)6942-0.0100.1470No
198CDK5R1CDK5R1
Entrez,  Source
cyclin-dependent kinase 5, regulatory subunit 1 (p35)6951-0.0100.1467No
199FOXC2FOXC2
Entrez,  Source
forkhead box C2 (MFH-1, mesenchyme forkhead 1)6970-0.0100.1457No
200DLX5DLX5
Entrez,  Source
distal-less homeobox 57118-0.0120.1349No
201UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase7435-0.0160.1112No
202NDUFS4NDUFS4
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)7499-0.0170.1069No
203KLK8KLK8
Entrez,  Source
kallikrein 8 (neuropsin/ovasin)7500-0.0170.1075No
204VAMP5VAMP5
Entrez,  Source
vesicle-associated membrane protein 5 (myobrevin)7502-0.0170.1080No
205CSDE1CSDE1
Entrez,  Source
cold shock domain containing E1, RNA-binding7535-0.0170.1062No
206HRASHRAS
Entrez,  Source
v-Ha-ras Harvey rat sarcoma viral oncogene homolog7568-0.0180.1044No
207MYEF2MYEF2
Entrez,  Source
myelin expression factor 27749-0.0200.0913No
208MKKSMKKS
Entrez,  Source
McKusick-Kaufman syndrome7767-0.0200.0907No
209NPR1NPR1
Entrez,  Source
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)7769-0.0200.0913No
210TBX5TBX5
Entrez,  Source
T-box 57774-0.0200.0918No
211ALKALK
Entrez,  Source
anaplastic lymphoma kinase (Ki-1)7874-0.0220.0849No
212SOD1SOD1
Entrez,  Source
superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))7962-0.0230.0791No
213IL2IL2
Entrez,  Source
interleukin 28058-0.0240.0727No
214DYRK3DYRK3
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 38086-0.0250.0715No
215ENGENG
Entrez,  Source
endoglin (Osler-Rendu-Weber syndrome 1)8089-0.0250.0722No
216MBNL1MBNL1
Entrez,  Source
muscleblind-like (Drosophila)8090-0.0250.0731No
217SUFUSUFU
Entrez,  Source
suppressor of fused homolog (Drosophila)8127-0.0250.0712No
218TNNI3TNNI3
Entrez,  Source
troponin I type 3 (cardiac)8145-0.0260.0709No
219PCSK9PCSK9
Entrez,  Source
proprotein convertase subtilisin/kexin type 98218-0.0270.0663No
220NF1NF1
Entrez,  Source
neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)8226-0.0270.0667No
221MYST3MYST3
Entrez,  Source
MYST histone acetyltransferase (monocytic leukemia) 38296-0.0280.0624No
222HEY1HEY1
Entrez,  Source
hairy/enhancer-of-split related with YRPW motif 18303-0.0280.0629No
223C1GALT1C1GALT1
Entrez,  Source
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 18461-0.0300.0520No
224BAXBAX
Entrez,  Source
BCL2-associated X protein8544-0.0310.0468No
225EIF2B4EIF2B4
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa8566-0.0320.0463No
226CARTPTCARTPT
Entrez,  Source
CART prepropeptide8608-0.0320.0443No
227RASGRP4RASGRP4
Entrez,  Source
RAS guanyl releasing protein 48642-0.0330.0430No
228ELNELN
Entrez,  Source
elastin (supravalvular aortic stenosis, Williams-Beuren syndrome)8687-0.0330.0408No
229ETS1ETS1
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)8706-0.0340.0406No
230SCG2SCG2
Entrez,  Source
secretogranin II (chromogranin C)8730-0.0340.0401No
231CASQ2CASQ2
Entrez,  Source
calsequestrin 2 (cardiac muscle)8759-0.0340.0391No
232UTRNUTRN
Entrez,  Source
utrophin (homologous to dystrophin)8805-0.0350.0369No
233PAX6PAX6
Entrez,  Source
paired box gene 6 (aniridia, keratitis)8836-0.0350.0359No
234SMAD2SMAD2
Entrez,  Source
SMAD, mothers against DPP homolog 2 (Drosophila)8847-0.0350.0364No
235IL7IL7
Entrez,  Source
interleukin 78864-0.0360.0364No
236SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 18926-0.0360.0330No
237STX2STX2
Entrez,  Source
syntaxin 28992-0.0370.0294No
238SPP2SPP2
Entrez,  Source
secreted phosphoprotein 2, 24kDa9005-0.0380.0298No
239TLE3TLE3
Entrez,  Source
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)9039-0.0380.0286No
240CMKLR1CMKLR1
Entrez,  Source
chemokine-like receptor 19069-0.0380.0278No
241NME2NME2
Entrez,  Source
non-metastatic cells 2, protein (NM23B) expressed in9131-0.0390.0245No
242DMRT1DMRT1
Entrez,  Source
doublesex and mab-3 related transcription factor 19294-0.0420.0136No
243DVL1DVL1
Entrez,  Source
dishevelled, dsh homolog 1 (Drosophila)9309-0.0420.0140No
244ITGA7ITGA7
Entrez,  Source
integrin, alpha 79373-0.0430.0107No
245GLMNGLMN
Entrez,  Source
glomulin, FKBP associated protein9440-0.0440.0072No
246NCLNCL
Entrez,  Source
nucleolin9448-0.0440.0082No
247PAX4PAX4
Entrez,  Source
paired box gene 49459-0.0440.0090No
248PTCH1PTCH1
Entrez,  Source
patched homolog 1 (Drosophila)9519-0.0450.0061No
249CDK6CDK6
Entrez,  Source
cyclin-dependent kinase 69565-0.0460.0043No
250RASA1RASA1
Entrez,  Source
RAS p21 protein activator (GTPase activating protein) 19586-0.0470.0045No
251MAFBMAFB
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)9601-0.0470.0051No
252ACIN1ACIN1
Entrez,  Source
apoptotic chromatin condensation inducer 19611-0.0470.0061No
253ACVR1ACVR1
Entrez,  Source
activin A receptor, type I9665-0.0480.0037No
254MSX2MSX2
Entrez,  Source
msh homeobox homolog 2 (Drosophila)9667-0.0480.0054No
255SNRKSNRK
Entrez,  Source
SNF related kinase9708-0.0490.0040No
256ATP2A2ATP2A2
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, slow twitch 29899-0.052-0.0087No
257LHCGRLHCGR
Entrez,  Source
luteinizing hormone/choriogonadotropin receptor9989-0.053-0.0136No
258ZBTB16ZBTB16
Entrez,  Source
zinc finger and BTB domain containing 1610088-0.055-0.0192No
259SART1SART1
Entrez,  Source
squamous cell carcinoma antigen recognised by T cells10089-0.055-0.0172No
260IL4IL4
Entrez,  Source
interleukin 410138-0.056-0.0189No
261IL18IL18
Entrez,  Source
interleukin 18 (interferon-gamma-inducing factor)10156-0.056-0.0182No
262COL10A1COL10A1
Entrez,  Source
collagen, type X, alpha 1(Schmid metaphyseal chondrodysplasia)10315-0.059-0.0282No
263COMPCOMP
Entrez,  Source
cartilage oligomeric matrix protein10344-0.059-0.0283No
264POU2F3POU2F3
Entrez,  Source
POU domain, class 2, transcription factor 310351-0.059-0.0266No
265IGF1IGF1
Entrez,  Source
insulin-like growth factor 1 (somatomedin C)10373-0.060-0.0261No
266RBP2RBP2
Entrez,  Source
retinol binding protein 2, cellular10395-0.060-0.0256No
267FOXE1FOXE1
Entrez,  Source
forkhead box E1 (thyroid transcription factor 2)10585-0.064-0.0378No
268MYH6MYH6
Entrez,  Source
myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)10594-0.064-0.0361No
269SFTPDSFTPD
Entrez,  Source
surfactant, pulmonary-associated protein D10726-0.067-0.0438No
270RNH1RNH1
Entrez,  Source
ribonuclease/angiogenin inhibitor 110745-0.067-0.0428No
271FGFR1FGFR1
Entrez,  Source
fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)10807-0.069-0.0450No
272GDF10GDF10
Entrez,  Source
growth differentiation factor 1010910-0.071-0.0503No
273MDKMDK
Entrez,  Source
midkine (neurite growth-promoting factor 2)10954-0.072-0.0510No
274TGFB3TGFB3
Entrez,  Source
transforming growth factor, beta 310957-0.072-0.0486No
275RETRET
Entrez,  Source
ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)11017-0.074-0.0505No
276RUNX1RUNX1
Entrez,  Source
runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)11134-0.077-0.0566No
277HAND1HAND1
Entrez,  Source
heart and neural crest derivatives expressed 111175-0.078-0.0569No
278SIX1SIX1
Entrez,  Source
sine oculis homeobox homolog 1 (Drosophila)11186-0.078-0.0549No
279POU6F1POU6F1
Entrez,  Source
POU domain, class 6, transcription factor 111253-0.080-0.0571No
280UFD1LUFD1L
Entrez,  Source
ubiquitin fusion degradation 1 like (yeast)11337-0.082-0.0605No
281SHOX2SHOX2
Entrez,  Source
short stature homeobox 211349-0.083-0.0584No
282GATA4GATA4
Entrez,  Source
GATA binding protein 411355-0.083-0.0558No
283ARSEARSE
Entrez,  Source
arylsulfatase E (chondrodysplasia punctata 1)11606-0.089-0.0718No
284ECE2ECE2
Entrez,  Source
endothelin converting enzyme 211609-0.089-0.0688No
285NPR3NPR3
Entrez,  Source
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)11674-0.091-0.0705No
286MTM1MTM1
Entrez,  Source
myotubularin 111733-0.093-0.0716No
287PAX3PAX3
Entrez,  Source
paired box gene 3 (Waardenburg syndrome 1)11737-0.093-0.0685No
288FRZBFRZB
Entrez,  Source
frizzled-related protein11835-0.097-0.0725No
289HMGCRHMGCR
Entrez,  Source
3-hydroxy-3-methylglutaryl-Coenzyme A reductase11844-0.097-0.0696No
290EBPEBP
Entrez,  Source
emopamil binding protein (sterol isomerase)11949-0.101-0.0740No
291ELF3ELF3
Entrez,  Source
E74-like factor 3 (ets domain transcription factor, epithelial-specific )12031-0.104-0.0765No
292EIF2B5EIF2B5
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa12127-0.108-0.0799No
293GPR56GPR56
Entrez,  Source
G protein-coupled receptor 5612282-0.115-0.0876No
294LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog12283-0.115-0.0835No
295INHAINHA
Entrez,  Source
inhibin, alpha12340-0.118-0.0836No
296GATA6GATA6
Entrez,  Source
GATA binding protein 612352-0.119-0.0802No
297HCKHCK
Entrez,  Source
hemopoietic cell kinase12385-0.120-0.0783No
298MUSKMUSK
Entrez,  Source
muscle, skeletal, receptor tyrosine kinase12426-0.123-0.0770No
299CENTA2CENTA2
Entrez,  Source
centaurin, alpha 212450-0.124-0.0743No
300RPS19RPS19
Entrez,  Source
ribosomal protein S1912470-0.125-0.0713No
301MYH9MYH9
Entrez,  Source
myosin, heavy chain 9, non-muscle12494-0.127-0.0685No
302NRD1NRD1
Entrez,  Source
nardilysin (N-arginine dibasic convertase)12495-0.127-0.0640No
303PPARDPPARD
Entrez,  Source
peroxisome proliferative activated receptor, delta12520-0.130-0.0612No
304MMP9MMP9
Entrez,  Source
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)12642-0.137-0.0656No
305DHCR24DHCR24
Entrez,  Source
24-dehydrocholesterol reductase12656-0.138-0.0616No
306IGFBP4IGFBP4
Entrez,  Source
insulin-like growth factor binding protein 412663-0.138-0.0571No
307UNC5CUNC5C
Entrez,  Source
unc-5 homolog C (C. elegans)12673-0.139-0.0528No
308TCF12TCF12
Entrez,  Source
transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)12682-0.140-0.0484No
309SECTM1SECTM1
Entrez,  Source
secreted and transmembrane 112728-0.144-0.0468No
310EGFEGF
Entrez,  Source
epidermal growth factor (beta-urogastrone)12737-0.145-0.0422No
311GHRGHR
Entrez,  Source
growth hormone receptor12744-0.146-0.0374No
312SRD5A2SRD5A2
Entrez,  Source
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)12820-0.155-0.0377No
313FGFR3FGFR3
Entrez,  Source
fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)12848-0.158-0.0341No
314KLK7KLK7
Entrez,  Source
kallikrein 7 (chymotryptic, stratum corneum)12860-0.160-0.0292No
315PLGPLG
Entrez,  Source
plasminogen12874-0.162-0.0244No
316GNPATGNPAT
Entrez,  Source
glyceronephosphate O-acyltransferase12889-0.163-0.0196No
317KLF10KLF10
Entrez,  Source
Kruppel-like factor 1012966-0.175-0.0192No
318FABP5FABP5
Entrez,  Source
fatty acid binding protein 5 (psoriasis-associated)12975-0.177-0.0135No
319NOTCH2NOTCH2
Entrez,  Source
Notch homolog 2 (Drosophila)13133-0.220-0.0177No
320COL5A3COL5A3
Entrez,  Source
collagen, type V, alpha 313187-0.246-0.0129No
321JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)13193-0.251-0.0043No
322CXCL10CXCL10
Entrez,  Source
chemokine (C-X-C motif) ligand 1013311-0.4390.0024No
Table: GSEA details [plain text format]



Fig 2: ORGAN_DEVELOPMENT   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ORGAN_DEVELOPMENT: Random ES distribution   
Gene set null distribution of ES for ORGAN_DEVELOPMENT