Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | PARP_KO_UP |
| Enrichment Score (ES) | 0.80248934 |
| Normalized Enrichment Score (NES) | 2.2357976 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 11 | 0.815 | 0.2128 | Yes |
| 2 | TINAGL1 | TINAGL1 Entrez, Source | tubulointerstitial nephritis antigen-like 1 | 39 | 0.622 | 0.3737 | Yes |
| 3 | MGP | MGP Entrez, Source | matrix Gla protein | 62 | 0.533 | 0.5117 | Yes |
| 4 | FST | FST Entrez, Source | follistatin | 132 | 0.388 | 0.6082 | Yes |
| 5 | GPX3 | GPX3 Entrez, Source | glutathione peroxidase 3 (plasma) | 286 | 0.256 | 0.6638 | Yes |
| 6 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 402 | 0.209 | 0.7099 | Yes |
| 7 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 406 | 0.208 | 0.7642 | Yes |
| 8 | NOV | NOV Entrez, Source | nephroblastoma overexpressed gene | 521 | 0.179 | 0.8025 | Yes |
| 9 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 1062 | 0.117 | 0.7925 | No |
| 10 | DCN | DCN Entrez, Source | decorin | 3029 | 0.048 | 0.6574 | No |
| 11 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 3298 | 0.043 | 0.6484 | No |
| 12 | CTTN | CTTN Entrez, Source | cortactin | 3493 | 0.039 | 0.6440 | No |
| 13 | AK1 | AK1 Entrez, Source | adenylate kinase 1 | 4876 | 0.017 | 0.5447 | No |
| 14 | B2M | B2M Entrez, Source | beta-2-microglobulin | 4992 | 0.015 | 0.5401 | No |
| 15 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 5296 | 0.011 | 0.5203 | No |
| 16 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 5875 | 0.004 | 0.4778 | No |
| 17 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5938 | 0.003 | 0.4739 | No |
| 18 | IGFBP6 | IGFBP6 Entrez, Source | insulin-like growth factor binding protein 6 | 6428 | -0.004 | 0.4381 | No |
| 19 | CD81 | CD81 Entrez, Source | CD81 molecule | 6698 | -0.007 | 0.4198 | No |
| 20 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 7976 | -0.023 | 0.3300 | No |
| 21 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 8130 | -0.026 | 0.3252 | No |
| 22 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 8169 | -0.026 | 0.3292 | No |
| 23 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 8687 | -0.033 | 0.2991 | No |
| 24 | EEF2 | EEF2 Entrez, Source | eukaryotic translation elongation factor 2 | 9999 | -0.053 | 0.2147 | No |
| 25 | IGFBP4 | IGFBP4 Entrez, Source | insulin-like growth factor binding protein 4 | 12663 | -0.138 | 0.0510 | No |
