Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | PASSERINI_GROWTH |
| Enrichment Score (ES) | 0.7113162 |
| Normalized Enrichment Score (NES) | 2.0391803 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0035434174 |
| FWER p-Value | 0.106 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 32 | 0.660 | 0.1918 | Yes |
| 2 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 113 | 0.410 | 0.3065 | Yes |
| 3 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 367 | 0.223 | 0.3531 | Yes |
| 4 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 372 | 0.219 | 0.4173 | Yes |
| 5 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 480 | 0.186 | 0.4640 | Yes |
| 6 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 496 | 0.183 | 0.5166 | Yes |
| 7 | NOV | NOV Entrez, Source | nephroblastoma overexpressed gene | 521 | 0.179 | 0.5674 | Yes |
| 8 | IGFBP1 | IGFBP1 Entrez, Source | insulin-like growth factor binding protein 1 | 531 | 0.177 | 0.6188 | Yes |
| 9 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 699 | 0.150 | 0.6505 | Yes |
| 10 | IFRD1 | IFRD1 Entrez, Source | interferon-related developmental regulator 1 | 841 | 0.135 | 0.6797 | Yes |
| 11 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 1192 | 0.110 | 0.6857 | Yes |
| 12 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 1267 | 0.106 | 0.7113 | Yes |
| 13 | LTBP2 | LTBP2 Entrez, Source | latent transforming growth factor beta binding protein 2 | 1980 | 0.074 | 0.6795 | No |
| 14 | PDGFRB | PDGFRB Entrez, Source | platelet-derived growth factor receptor, beta polypeptide | 2871 | 0.051 | 0.6278 | No |
| 15 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 3414 | 0.040 | 0.5989 | No |
| 16 | KIT | KIT Entrez, Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 4345 | 0.025 | 0.5363 | No |
| 17 | INHBA | INHBA Entrez, Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 4596 | 0.021 | 0.5238 | No |
| 18 | KDR | KDR Entrez, Source | kinase insert domain receptor (a type III receptor tyrosine kinase) | 4694 | 0.020 | 0.5223 | No |
| 19 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 4953 | 0.016 | 0.5076 | No |
| 20 | TGFBR2 | TGFBR2 Entrez, Source | transforming growth factor, beta receptor II (70/80kDa) | 5298 | 0.011 | 0.4850 | No |
| 21 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 5527 | 0.008 | 0.4702 | No |
| 22 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 5875 | 0.004 | 0.4452 | No |
| 23 | TGFA | TGFA Entrez, Source | transforming growth factor, alpha | 7317 | -0.014 | 0.3412 | No |
| 24 | PDGFRA | PDGFRA Entrez, Source | platelet-derived growth factor receptor, alpha polypeptide | 7343 | -0.015 | 0.3437 | No |
| 25 | PDGFRL | PDGFRL Entrez, Source | platelet-derived growth factor receptor-like | 8576 | -0.032 | 0.2606 | No |
| 26 | PGF | PGF Entrez, Source | placental growth factor, vascular endothelial growth factor-related protein | 9350 | -0.043 | 0.2150 | No |
| 27 | FGF1 | FGF1 Entrez, Source | fibroblast growth factor 1 (acidic) | 10275 | -0.058 | 0.1627 | No |
| 28 | EDN2 | EDN2 Entrez, Source | endothelin 2 | 11417 | -0.084 | 0.1018 | No |
| 29 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 12737 | -0.145 | 0.0454 | No |
