Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | PASSERINI_PROLIFERATION |
| Enrichment Score (ES) | 0.5466925 |
| Normalized Enrichment Score (NES) | 1.760034 |
| Nominal p-value | 0.0068728523 |
| FDR q-value | 0.038960993 |
| FWER p-Value | 0.996 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 5 | 0.972 | 0.1795 | Yes |
| 2 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 44 | 0.606 | 0.2889 | Yes |
| 3 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 113 | 0.410 | 0.3597 | Yes |
| 4 | PTK2B | PTK2B Entrez, Source | PTK2B protein tyrosine kinase 2 beta | 279 | 0.262 | 0.3958 | Yes |
| 5 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 367 | 0.223 | 0.4305 | Yes |
| 6 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 496 | 0.183 | 0.4547 | Yes |
| 7 | IL8RB | IL8RB Entrez, Source | interleukin 8 receptor, beta | 520 | 0.179 | 0.4861 | Yes |
| 8 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 699 | 0.150 | 0.5005 | Yes |
| 9 | HBEGF | HBEGF Entrez, Source | heparin-binding EGF-like growth factor | 717 | 0.149 | 0.5268 | Yes |
| 10 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 1086 | 0.116 | 0.5205 | Yes |
| 11 | IL10 | IL10 Entrez, Source | interleukin 10 | 1329 | 0.102 | 0.5213 | Yes |
| 12 | VHL | VHL Entrez, Source | von Hippel-Lindau tumor suppressor | 1336 | 0.102 | 0.5397 | Yes |
| 13 | CLK1 | CLK1 Entrez, Source | CDC-like kinase 1 | 1597 | 0.089 | 0.5367 | Yes |
| 14 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 1676 | 0.086 | 0.5467 | Yes |
| 15 | TACSTD2 | TACSTD2 Entrez, Source | tumor-associated calcium signal transducer 2 | 2200 | 0.067 | 0.5198 | No |
| 16 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 2324 | 0.064 | 0.5224 | No |
| 17 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 2895 | 0.051 | 0.4889 | No |
| 18 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 3256 | 0.044 | 0.4699 | No |
| 19 | PMP22 | PMP22 Entrez, Source | peripheral myelin protein 22 | 3464 | 0.039 | 0.4616 | No |
| 20 | TSHR | TSHR Entrez, Source | thyroid stimulating hormone receptor | 3712 | 0.035 | 0.4495 | No |
| 21 | PRKRA | PRKRA Entrez, Source | protein kinase, interferon-inducible double stranded RNA dependent activator | 4030 | 0.030 | 0.4311 | No |
| 22 | TSPAN5 | TSPAN5 Entrez, Source | tetraspanin 5 | 4392 | 0.024 | 0.4084 | No |
| 23 | LAMP3 | LAMP3 Entrez, Source | lysosomal-associated membrane protein 3 | 4726 | 0.019 | 0.3869 | No |
| 24 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 4953 | 0.016 | 0.3728 | No |
| 25 | IL1A | IL1A Entrez, Source | interleukin 1, alpha | 5162 | 0.013 | 0.3596 | No |
| 26 | NF2 | NF2 Entrez, Source | neurofibromin 2 (bilateral acoustic neuroma) | 5466 | 0.009 | 0.3384 | No |
| 27 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 5527 | 0.008 | 0.3354 | No |
| 28 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5938 | 0.003 | 0.3051 | No |
| 29 | MAPRE1 | MAPRE1 Entrez, Source | microtubule-associated protein, RP/EB family, member 1 | 6226 | -0.001 | 0.2837 | No |
| 30 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 6239 | -0.001 | 0.2830 | No |
| 31 | TNFSF4 | TNFSF4 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa) | 6705 | -0.007 | 0.2494 | No |
| 32 | SPOCK1 | SPOCK1 Entrez, Source | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 7173 | -0.013 | 0.2166 | No |
| 33 | TGFA | TGFA Entrez, Source | transforming growth factor, alpha | 7317 | -0.014 | 0.2085 | No |
| 34 | PDGFRA | PDGFRA Entrez, Source | platelet-derived growth factor receptor, alpha polypeptide | 7343 | -0.015 | 0.2093 | No |
| 35 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 7976 | -0.023 | 0.1661 | No |
| 36 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 8322 | -0.028 | 0.1453 | No |
| 37 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 8706 | -0.034 | 0.1228 | No |
| 38 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 8731 | -0.034 | 0.1273 | No |
| 39 | TNFSF11 | TNFSF11 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 11 | 8840 | -0.035 | 0.1257 | No |
| 40 | NUDC | NUDC Entrez, Source | nuclear distribution gene C homolog (A. nidulans) | 9037 | -0.038 | 0.1180 | No |
| 41 | ARHGEF1 | ARHGEF1 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 1 | 9085 | -0.039 | 0.1216 | No |
| 42 | PGF | PGF Entrez, Source | placental growth factor, vascular endothelial growth factor-related protein | 9350 | -0.043 | 0.1096 | No |
| 43 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9987 | -0.053 | 0.0716 | No |
| 44 | PBEF1 | PBEF1 Entrez, Source | pre-B-cell colony enhancing factor 1 | 10279 | -0.058 | 0.0605 | No |
| 45 | UBE2V2 | UBE2V2 Entrez, Source | ubiquitin-conjugating enzyme E2 variant 2 | 10326 | -0.059 | 0.0680 | No |
| 46 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 12189 | -0.111 | -0.0516 | No |
| 47 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 12737 | -0.145 | -0.0659 | No |
| 48 | PLG | PLG Entrez, Source | plasminogen | 12874 | -0.162 | -0.0462 | No |
| 49 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 13311 | -0.439 | 0.0023 | No |
