Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_72h
GeneSetPENG_GLUTAMINE_DN
Enrichment Score (ES)-0.3412354
Normalized Enrichment Score (NES)-1.4688557
Nominal p-value0.0060975607
FDR q-value0.37899005
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: PENG_GLUTAMINE_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PFKPPFKP
Entrez,  Source
phosphofructokinase, platelet520.5760.0446No
2LDHBLDHB
Entrez,  Source
lactate dehydrogenase B610.5550.0907No
3HSPA4HSPA4
Entrez,  Source
heat shock 70kDa protein 41920.3280.1084No
4EMP3EMP3
Entrez,  Source
epithelial membrane protein 33580.2270.1149No
5CLIC1CLIC1
Entrez,  Source
chloride intracellular channel 14630.1920.1232No
6KHSRPKHSRP
Entrez,  Source
KH-type splicing regulatory protein (FUSE binding protein 2)9770.1230.0946No
7GJB1GJB1
Entrez,  Source
gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)13800.1000.0725No
8TGFB1TGFB1
Entrez,  Source
transforming growth factor, beta 1 (Camurati-Engelmann disease)20790.0710.0254No
9ALDOAALDOA
Entrez,  Source
aldolase A, fructose-bisphosphate21400.0690.0266No
10PSMD8PSMD8
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 824410.0610.0090No
11SLC19A1SLC19A1
Entrez,  Source
solute carrier family 19 (folate transporter), member 127260.054-0.0080No
12PSMA6PSMA6
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 627340.054-0.0040No
13CYCSCYCS
Entrez,  Source
cytochrome c, somatic33720.041-0.0489No
14MYD88MYD88
Entrez,  Source
myeloid differentiation primary response gene (88)34710.039-0.0531No
15IDH3AIDH3A
Entrez,  Source
isocitrate dehydrogenase 3 (NAD+) alpha35050.039-0.0523No
16CDC25ACDC25A
Entrez,  Source
cell division cycle 25A35680.037-0.0539No
17SYNGR2SYNGR2
Entrez,  Source
synaptogyrin 236120.037-0.0541No
18SF3B4SF3B4
Entrez,  Source
splicing factor 3b, subunit 4, 49kDa36180.037-0.0514No
19CELSR2CELSR2
Entrez,  Source
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)38800.032-0.0685No
20LDHALDHA
Entrez,  Source
lactate dehydrogenase A39150.032-0.0684No
21TXNIPTXNIP
Entrez,  Source
thioredoxin interacting protein39750.031-0.0703No
22PSMD1PSMD1
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 140430.030-0.0729No
23KPNA2KPNA2
Entrez,  Source
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)41090.029-0.0755No
24TUBG1TUBG1
Entrez,  Source
tubulin, gamma 142120.027-0.0810No
25NUP98NUP98
Entrez,  Source
nucleoporin 98kDa42170.027-0.0790No
26PIK3R3PIK3R3
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)42510.026-0.0793No
27EIF5EIF5
Entrez,  Source
eukaryotic translation initiation factor 543150.025-0.0820No
28BCAP31BCAP31
Entrez,  Source
B-cell receptor-associated protein 3143390.025-0.0816No
29HSPA8HSPA8
Entrez,  Source
heat shock 70kDa protein 845370.022-0.0948No
30MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1147270.019-0.1075No
31NMT1NMT1
Entrez,  Source
N-myristoyltransferase 149050.017-0.1195No
32PPP2R2APPP2R2A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform49680.016-0.1229No
33SCDSCD
Entrez,  Source
stearoyl-CoA desaturase (delta-9-desaturase)50350.015-0.1267No
34PGAM1PGAM1
Entrez,  Source
phosphoglycerate mutase 1 (brain)52460.012-0.1416No
35PPIBPPIB
Entrez,  Source
peptidylprolyl isomerase B (cyclophilin B)57130.006-0.1766No
36ATP5G3ATP5G3
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)57420.005-0.1783No
37PSMD12PSMD12
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1257810.005-0.1808No
38PPIFPPIF
Entrez,  Source
peptidylprolyl isomerase F (cyclophilin F)59130.003-0.1905No
39ODC1ODC1
Entrez,  Source
ornithine decarboxylase 159740.002-0.1948No
40VDAC1VDAC1
Entrez,  Source
voltage-dependent anion channel 161350.000-0.2069No
41TOP1TOP1
Entrez,  Source
topoisomerase (DNA) I6189-0.000-0.2109No
42IFI30IFI30
Entrez,  Source
interferon, gamma-inducible protein 306191-0.000-0.2110No
43CCT6ACCT6A
Entrez,  Source
chaperonin containing TCP1, subunit 6A (zeta 1)6256-0.001-0.2157No
44ATP1B3ATP1B3
Entrez,  Source
ATPase, Na+/K+ transporting, beta 3 polypeptide6301-0.002-0.2189No
45LAMB3LAMB3
Entrez,  Source
laminin, beta 36323-0.002-0.2203No
46HSPA5HSPA5
Entrez,  Source
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)6557-0.005-0.2376No
47DNAJB6DNAJB6
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 66644-0.006-0.2436No
48TFRCTFRC
Entrez,  Source
transferrin receptor (p90, CD71)6700-0.007-0.2472No
49PRDX1PRDX1
Entrez,  Source
peroxiredoxin 16870-0.009-0.2592No
50PSMB3PSMB3
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 36921-0.010-0.2622No
51TCEB1TCEB1
Entrez,  Source
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)6931-0.010-0.2621No
52ADRM1ADRM1
Entrez,  Source
adhesion regulating molecule 16953-0.010-0.2628No
53OGFROGFR
Entrez,  Source
opioid growth factor receptor6989-0.011-0.2646No
54ADAM19ADAM19
Entrez,  Source
ADAM metallopeptidase domain 19 (meltrin beta)7040-0.011-0.2674No
55PFN1PFN1
Entrez,  Source
profilin 17229-0.013-0.2806No
56PTMSPTMS
Entrez,  Source
parathymosin7316-0.014-0.2859No
57LMNB1LMNB1
Entrez,  Source
lamin B17411-0.015-0.2917No
58VCPVCP
Entrez,  Source
valosin-containing protein7423-0.016-0.2913No
59GRIN2AGRIN2A
Entrez,  Source
glutamate receptor, ionotropic, N-methyl D-aspartate 2A7544-0.017-0.2989No
60HRASHRAS
Entrez,  Source
v-Ha-ras Harvey rat sarcoma viral oncogene homolog7568-0.018-0.2992No
61MORF4L2MORF4L2
Entrez,  Source
mortality factor 4 like 27580-0.018-0.2985No
62PSMD3PSMD3
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 37666-0.019-0.3034No
63HSPE1HSPE1
Entrez,  Source
heat shock 10kDa protein 1 (chaperonin 10)7672-0.019-0.3021No
64DNAJA1DNAJA1
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily A, member 17683-0.019-0.3013No
65IDH1IDH1
Entrez,  Source
isocitrate dehydrogenase 1 (NADP+), soluble7828-0.021-0.3104No
66COPS3COPS3
Entrez,  Source
COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)7930-0.022-0.3162No
67CCNB1CCNB1
Entrez,  Source
cyclin B18004-0.024-0.3198No
68SFRS2SFRS2
Entrez,  Source
splicing factor, arginine/serine-rich 28111-0.025-0.3257No
69NDUFS6NDUFS6
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)8128-0.025-0.3248No
70CCT2CCT2
Entrez,  Source
chaperonin containing TCP1, subunit 2 (beta)8167-0.026-0.3255No
71RANGAP1RANGAP1
Entrez,  Source
Ran GTPase activating protein 18169-0.026-0.3234No
72PHBPHB
Entrez,  Source
prohibitin8324-0.028-0.3327No
73UBE2NUBE2N
Entrez,  Source
ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)8325-0.028-0.3303No
74BMS1LBMS1L
Entrez,  Source
BMS1-like, ribosome assembly protein (yeast)8437-0.030-0.3362No
75EIF4G2EIF4G2
Entrez,  Source
eukaryotic translation initiation factor 4 gamma, 28447-0.030-0.3344No
76RNASEH1RNASEH1
Entrez,  Source
ribonuclease H18474-0.031-0.3338No
77TCP1TCP1
Entrez,  Source
t-complex 18504-0.031-0.3334No
78CCND1CCND1
Entrez,  Source
cyclin D18524-0.031-0.3322No
79ADCY3ADCY3
Entrez,  Source
adenylate cyclase 38531-0.031-0.3301No
80EIF2B4EIF2B4
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa8566-0.032-0.3300No
81BZW1BZW1
Entrez,  Source
basic leucine zipper and W2 domains 18626-0.033-0.3317No
82PRPS1PRPS1
Entrez,  Source
phosphoribosyl pyrophosphate synthetase 18663-0.033-0.3316No
83CALRCALR
Entrez,  Source
calreticulin8727-0.034-0.3336No
84UMPSUMPS
Entrez,  Source
uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase)8780-0.035-0.3346No
85RBBP6RBBP6
Entrez,  Source
retinoblastoma binding protein 68839-0.035-0.3360No
86BOP1BOP1
Entrez,  Source
block of proliferation 18881-0.036-0.3361No
87SLC4A7SLC4A7
Entrez,  Source
solute carrier family 4, sodium bicarbonate cotransporter, member 78929-0.037-0.3366No
88POLR2CPOLR2C
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa8936-0.037-0.3340No
89EIF5AEIF5A
Entrez,  Source
eukaryotic translation initiation factor 5A8947-0.037-0.3316No
90GCSHGCSH
Entrez,  Source
glycine cleavage system protein H (aminomethyl carrier)8961-0.037-0.3295No
91GSPT1GSPT1
Entrez,  Source
G1 to S phase transition 18969-0.037-0.3269No
92NUDCNUDC
Entrez,  Source
nuclear distribution gene C homolog (A. nidulans)9037-0.038-0.3288No
93PABPN1PABPN1
Entrez,  Source
poly(A) binding protein, nuclear 19064-0.038-0.3275No
94HNRPABHNRPAB
Entrez,  Source
heterogeneous nuclear ribonucleoprotein A/B9101-0.039-0.3270No
95PPP1R10PPP1R10
Entrez,  Source
protein phosphatase 1, regulatory subunit 109190-0.040-0.3303No
96TRIP13TRIP13
Entrez,  Source
thyroid hormone receptor interactor 139335-0.042-0.3377Yes
97SSBP1SSBP1
Entrez,  Source
single-stranded DNA binding protein 19358-0.043-0.3358Yes
98DKC1DKC1
Entrez,  Source
dyskeratosis congenita 1, dyskerin9386-0.043-0.3342Yes
99NCLNCL
Entrez,  Source
nucleolin9448-0.044-0.3351Yes
100DHCR7DHCR7
Entrez,  Source
7-dehydrocholesterol reductase9455-0.044-0.3318Yes
101TOMM40TOMM40
Entrez,  Source
translocase of outer mitochondrial membrane 40 homolog (yeast)9457-0.044-0.3282Yes
102CCT5CCT5
Entrez,  Source
chaperonin containing TCP1, subunit 5 (epsilon)9486-0.045-0.3265Yes
103PRPF4PRPF4
Entrez,  Source
PRP4 pre-mRNA processing factor 4 homolog (yeast)9579-0.046-0.3296Yes
104MRPL12MRPL12
Entrez,  Source
mitochondrial ribosomal protein L129628-0.047-0.3292Yes
105SQLESQLE
Entrez,  Source
squalene epoxidase9644-0.048-0.3264Yes
106TARDBPTARDBP
Entrez,  Source
TAR DNA binding protein9687-0.048-0.3255Yes
107ABCF1ABCF1
Entrez,  Source
ATP-binding cassette, sub-family F (GCN20), member 19738-0.049-0.3251Yes
108PRODHPRODH
Entrez,  Source
proline dehydrogenase (oxidase) 19764-0.050-0.3229Yes
109AK2AK2
Entrez,  Source
adenylate kinase 29770-0.050-0.3190Yes
110G3BPG3BP
Entrez,  Source
-9801-0.050-0.3171Yes
111RQCD1RQCD1
Entrez,  Source
RCD1 required for cell differentiation1 homolog (S. pombe)9821-0.051-0.3143Yes
112HPRT1HPRT1
Entrez,  Source
hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)9884-0.052-0.3146Yes
113ATP2A2ATP2A2
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, slow twitch 29899-0.052-0.3113Yes
114PIK3R2PIK3R2
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)9995-0.053-0.3141Yes
115BYSLBYSL
Entrez,  Source
bystin-like10106-0.055-0.3178Yes
116PTDSS1PTDSS1
Entrez,  Source
phosphatidylserine synthase 110150-0.056-0.3163Yes
117ALG8ALG8
Entrez,  Source
asparagine-linked glycosylation 8 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase)10169-0.056-0.3130Yes
118GMPSGMPS
Entrez,  Source
guanine monphosphate synthetase10172-0.056-0.3084Yes
119XRCC5XRCC5
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)10199-0.057-0.3056Yes
120RUVBL2RUVBL2
Entrez,  Source
RuvB-like 2 (E. coli)10227-0.057-0.3028Yes
121RABGGTBRABGGTB
Entrez,  Source
Rab geranylgeranyltransferase, beta subunit10378-0.060-0.3092Yes
122TIMM17ATIMM17A
Entrez,  Source
translocase of inner mitochondrial membrane 17 homolog A (yeast)10415-0.061-0.3068Yes
123EWSR1EWSR1
Entrez,  Source
Ewing sarcoma breakpoint region 110419-0.061-0.3019Yes
124SYNCRIPSYNCRIP
Entrez,  Source
synaptotagmin binding, cytoplasmic RNA interacting protein10434-0.061-0.2979Yes
125FBLFBL
Entrez,  Source
fibrillarin10535-0.063-0.3002Yes
126PSMB6PSMB6
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 610550-0.063-0.2959Yes
127HNRPLHNRPL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein L10566-0.064-0.2917Yes
128ACLYACLY
Entrez,  Source
ATP citrate lyase10700-0.066-0.2962Yes
129RPS26RPS26
Entrez,  Source
ribosomal protein S2610735-0.067-0.2932Yes
130SGTASGTA
Entrez,  Source
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha10760-0.067-0.2893Yes
131TBL3TBL3
Entrez,  Source
transducin (beta)-like 310783-0.068-0.2853Yes
132STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa10803-0.068-0.2809Yes
133SRPK1SRPK1
Entrez,  Source
SFRS protein kinase 110895-0.071-0.2819Yes
134PAICSPAICS
Entrez,  Source
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase10929-0.072-0.2784Yes
135RNF126RNF126
Entrez,  Source
ring finger protein 12610941-0.072-0.2732Yes
136PDCD4PDCD4
Entrez,  Source
programmed cell death 4 (neoplastic transformation inhibitor)10963-0.073-0.2687Yes
137SSBSSB
Entrez,  Source
Sjogren syndrome antigen B (autoantigen La)10994-0.073-0.2648Yes
138KARSKARS
Entrez,  Source
lysyl-tRNA synthetase11005-0.073-0.2594Yes
139SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like11182-0.078-0.2662Yes
140CDC20CDC20
Entrez,  Source
CDC20 cell division cycle 20 homolog (S. cerevisiae)11187-0.078-0.2599Yes
141MRPL23MRPL23
Entrez,  Source
mitochondrial ribosomal protein L2311272-0.081-0.2595Yes
142MTHFD1MTHFD1
Entrez,  Source
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase11282-0.081-0.2534Yes
143CTSCCTSC
Entrez,  Source
cathepsin C11373-0.083-0.2532Yes
144DDX18DDX18
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 1811433-0.085-0.2506Yes
145C1QBPC1QBP
Entrez,  Source
complement component 1, q subcomponent binding protein11506-0.086-0.2488Yes
146EBNA1BP2EBNA1BP2
Entrez,  Source
EBNA1 binding protein 211605-0.089-0.2487Yes
147FDFT1FDFT1
Entrez,  Source
farnesyl-diphosphate farnesyltransferase 111716-0.093-0.2493Yes
148PRDX4PRDX4
Entrez,  Source
peroxiredoxin 411781-0.095-0.2462Yes
149NOL5ANOL5A
Entrez,  Source
nucleolar protein 5A (56kDa with KKE/D repeat)11821-0.096-0.2410Yes
150DDX1DDX1
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 111880-0.098-0.2371Yes
151EIF4G1EIF4G1
Entrez,  Source
eukaryotic translation initiation factor 4 gamma, 111909-0.100-0.2309Yes
152NME1NME1
Entrez,  Source
non-metastatic cells 1, protein (NM23A) expressed in11914-0.100-0.2228Yes
153TAP1TAP1
Entrez,  Source
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)11920-0.100-0.2148Yes
154EBPEBP
Entrez,  Source
emopamil binding protein (sterol isomerase)11949-0.101-0.2084Yes
155PTPN6PTPN6
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 612001-0.103-0.2036Yes
156PSME4PSME4
Entrez,  Source
proteasome (prosome, macropain) activator subunit 412096-0.107-0.2018Yes
157SLC29A2SLC29A2
Entrez,  Source
solute carrier family 29 (nucleoside transporters), member 212103-0.107-0.1932Yes
158SLC5A6SLC5A6
Entrez,  Source
solute carrier family 5 (sodium-dependent vitamin transporter), member 612113-0.108-0.1848Yes
159ALG3ALG3
Entrez,  Source
asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase)12125-0.108-0.1765Yes
160EIF2B5EIF2B5
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa12127-0.108-0.1674Yes
161CHD4CHD4
Entrez,  Source
chromodomain helicase DNA binding protein 412144-0.109-0.1595Yes
162IDI1IDI1
Entrez,  Source
isopentenyl-diphosphate delta isomerase 112159-0.110-0.1513Yes
163AMD1AMD1
Entrez,  Source
adenosylmethionine decarboxylase 112195-0.111-0.1446Yes
164FUSFUS
Entrez,  Source
fusion (involved in t(12;16) in malignant liposarcoma)12205-0.112-0.1359Yes
165XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)12235-0.113-0.1286Yes
166FKBP4FKBP4
Entrez,  Source
FK506 binding protein 4, 59kDa12376-0.120-0.1291Yes
167PRKCBP1PRKCBP1
Entrez,  Source
protein kinase C binding protein 112402-0.121-0.1208Yes
168PA2G4PA2G4
Entrez,  Source
proliferation-associated 2G4, 38kDa12425-0.123-0.1121Yes
169NOLC1NOLC1
Entrez,  Source
nucleolar and coiled-body phosphoprotein 112447-0.123-0.1033Yes
170DHCR24DHCR24
Entrez,  Source
24-dehydrocholesterol reductase12656-0.138-0.1075Yes
171XBP1XBP1
Entrez,  Source
X-box binding protein 112661-0.138-0.0962Yes
172DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A12862-0.160-0.0979Yes
173TDGTDG
Entrez,  Source
thymine-DNA glycosylase12879-0.162-0.0855Yes
174INHBCINHBC
Entrez,  Source
inhibin, beta C12890-0.163-0.0725Yes
175SRMSRM
Entrez,  Source
spermidine synthase12923-0.168-0.0608Yes
176ACAT2ACAT2
Entrez,  Source
acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase)12976-0.177-0.0498Yes
177LIMK2LIMK2
Entrez,  Source
LIM domain kinase 213008-0.187-0.0365Yes
178SLC29A1SLC29A1
Entrez,  Source
solute carrier family 29 (nucleoside transporters), member 113027-0.192-0.0216Yes
179SFPQSFPQ
Entrez,  Source
splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)13196-0.252-0.0132Yes
180FASNFASN
Entrez,  Source
fatty acid synthase13241-0.2880.0077Yes
Table: GSEA details [plain text format]



Fig 2: PENG_GLUTAMINE_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PENG_GLUTAMINE_DN: Random ES distribution   
Gene set null distribution of ES for PENG_GLUTAMINE_DN