Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | RADAEVA_IFNA_UP |
| Enrichment Score (ES) | -0.56723756 |
| Normalized Enrichment Score (NES) | -1.8444073 |
| Nominal p-value | 0.0021413276 |
| FDR q-value | 0.09750374 |
| FWER p-Value | 0.773 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IFITM2 | IFITM2 Entrez, Source | interferon induced transmembrane protein 2 (1-8D) | 281 | 0.260 | 0.0440 | No |
| 2 | PLSCR1 | PLSCR1 Entrez, Source | phospholipid scramblase 1 | 1073 | 0.116 | 0.0135 | No |
| 3 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 1676 | 0.086 | -0.0103 | No |
| 4 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 2324 | 0.064 | -0.0430 | No |
| 5 | OAS1 | OAS1 Entrez, Source | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 4150 | 0.028 | -0.1731 | No |
| 6 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 4566 | 0.022 | -0.1990 | No |
| 7 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 4567 | 0.022 | -0.1936 | No |
| 8 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 5091 | 0.014 | -0.2294 | No |
| 9 | PIAS4 | PIAS4 Entrez, Source | protein inhibitor of activated STAT, 4 | 5686 | 0.006 | -0.2725 | No |
| 10 | KLK3 | KLK3 Entrez, Source | kallikrein 3, (prostate specific antigen) | 6910 | -0.010 | -0.3621 | No |
| 11 | UBE2L6 | UBE2L6 Entrez, Source | ubiquitin-conjugating enzyme E2L 6 | 7569 | -0.018 | -0.4071 | No |
| 12 | PHB | PHB Entrez, Source | prohibitin | 8324 | -0.028 | -0.4568 | No |
| 13 | BAX | BAX Entrez, Source | BCL2-associated X protein | 8544 | -0.031 | -0.4654 | No |
| 14 | CALR | CALR Entrez, Source | calreticulin | 8727 | -0.034 | -0.4706 | No |
| 15 | UBE2D3 | UBE2D3 Entrez, Source | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 8858 | -0.036 | -0.4715 | No |
| 16 | SOCS1 | SOCS1 Entrez, Source | suppressor of cytokine signaling 1 | 8877 | -0.036 | -0.4638 | No |
| 17 | ADAR | ADAR Entrez, Source | adenosine deaminase, RNA-specific | 8925 | -0.036 | -0.4583 | No |
| 18 | IRF7 | IRF7 Entrez, Source | interferon regulatory factor 7 | 9469 | -0.045 | -0.4880 | No |
| 19 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 9651 | -0.048 | -0.4896 | No |
| 20 | TUBB | TUBB Entrez, Source | tubulin, beta | 10340 | -0.059 | -0.5266 | No |
| 21 | MX2 | MX2 Entrez, Source | myxovirus (influenza virus) resistance 2 (mouse) | 10443 | -0.061 | -0.5190 | No |
| 22 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 10803 | -0.068 | -0.5288 | No |
| 23 | LGALS3BP | LGALS3BP Entrez, Source | lectin, galactoside-binding, soluble, 3 binding protein | 10919 | -0.071 | -0.5197 | No |
| 24 | IL12RB2 | IL12RB2 Entrez, Source | interleukin 12 receptor, beta 2 | 11553 | -0.088 | -0.5453 | Yes |
| 25 | IFIT2 | IFIT2 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 2 | 11566 | -0.088 | -0.5241 | Yes |
| 26 | IFITM3 | IFITM3 Entrez, Source | interferon induced transmembrane protein 3 (1-8U) | 11860 | -0.098 | -0.5217 | Yes |
| 27 | NTRK1 | NTRK1 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 1 | 11904 | -0.099 | -0.5001 | Yes |
| 28 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 12165 | -0.110 | -0.4922 | Yes |
| 29 | VAT1 | VAT1 Entrez, Source | vesicle amine transport protein 1 homolog (T californica) | 12333 | -0.118 | -0.4753 | Yes |
| 30 | BST2 | BST2 Entrez, Source | bone marrow stromal cell antigen 2 | 12353 | -0.119 | -0.4471 | Yes |
| 31 | AKR7A2 | AKR7A2 Entrez, Source | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 12358 | -0.119 | -0.4177 | Yes |
| 32 | IFI44 | IFI44 Entrez, Source | interferon-induced protein 44 | 12681 | -0.140 | -0.4070 | Yes |
| 33 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 12999 | -0.184 | -0.3848 | Yes |
| 34 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 13085 | -0.205 | -0.3400 | Yes |
| 35 | IFI35 | IFI35 Entrez, Source | interferon-induced protein 35 | 13106 | -0.211 | -0.2888 | Yes |
| 36 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 13311 | -0.439 | -0.1944 | Yes |
| 37 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13337 | -0.787 | 0.0004 | Yes |
