Details for gene set RAS_ONCOGENIC

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in class	double_gel_8d
GeneSet	RAS_ONCOGENIC_SIGNATURE
Enrichment Score (ES)	0.47378188
Normalized Enrichment Score (NES)	1.8057394
Nominal p-value	0.0
FDR q-value	0.031195035
FWER p-Value	0.968

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GDF15	GDF15 Entrez, Source	growth differentiation factor 15	58	0.559	0.0392	Yes
2	BMP2	BMP2 Entrez, Source	bone morphogenetic protein 2	91	0.451	0.0719	Yes
3	CXCL2	CXCL2 Entrez, Source	chemokine (C-X-C motif) ligand 2	118	0.402	0.1012	Yes
4	FOS	FOS Entrez, Source	v-fos FBJ murine osteosarcoma viral oncogene homolog	142	0.371	0.1283	Yes
5	ANGPTL4	ANGPTL4 Entrez, Source	angiopoietin-like 4	147	0.365	0.1564	Yes
6	CCL20	CCL20 Entrez, Source	chemokine (C-C motif) ligand 20	160	0.355	0.1831	Yes
7	PRNP	PRNP Entrez, Source	prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)	171	0.348	0.2095	Yes
8	CCNL1	CCNL1 Entrez, Source	cyclin L1	316	0.241	0.2174	Yes
9	GJB5	GJB5 Entrez, Source	gap junction protein, beta 5 (connexin 31.1)	322	0.239	0.2356	Yes
10	KLF6	KLF6 Entrez, Source	Kruppel-like factor 6	364	0.225	0.2500	Yes
11	TGFB2	TGFB2 Entrez, Source	transforming growth factor, beta 2	367	0.223	0.2672	Yes
12	S100A6	S100A6 Entrez, Source	S100 calcium binding protein A6	402	0.209	0.2809	Yes
13	TNFRSF12A	TNFRSF12A Entrez, Source	tumor necrosis factor receptor superfamily, member 12A	415	0.205	0.2960	Yes
14	SLC20A1	SLC20A1 Entrez, Source	solute carrier family 20 (phosphate transporter), member 1	543	0.173	0.2999	Yes
15	DUSP5	DUSP5 Entrez, Source	dual specificity phosphatase 5	553	0.172	0.3126	Yes
16	IER3	IER3 Entrez, Source	immediate early response 3	598	0.165	0.3221	Yes
17	ADAMTS5	ADAMTS5 Entrez, Source	ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2)	609	0.164	0.3341	Yes
18	PDGFA	PDGFA Entrez, Source	platelet-derived growth factor alpha polypeptide	619	0.162	0.3460	Yes
19	HBEGF	HBEGF Entrez, Source	heparin-binding EGF-like growth factor	717	0.149	0.3503	Yes
20	PHLDA1	PHLDA1 Entrez, Source	pleckstrin homology-like domain, family A, member 1	772	0.143	0.3573	Yes
21	KLF5	KLF5 Entrez, Source	Kruppel-like factor 5 (intestinal)	780	0.141	0.3678	Yes
22	JUNB	JUNB Entrez, Source	jun B proto-oncogene	866	0.132	0.3717	Yes
23	PALMD	PALMD Entrez, Source	palmdelphin	958	0.125	0.3745	Yes
24	IL1B	IL1B Entrez, Source	interleukin 1, beta	1014	0.121	0.3797	Yes
25	LIF	LIF Entrez, Source	leukemia inhibitory factor (cholinergic differentiation factor)	1037	0.118	0.3873	Yes
26	TRIB1	TRIB1 Entrez, Source	tribbles homolog 1 (Drosophila)	1067	0.116	0.3941	Yes
27	SLC16A3	SLC16A3 Entrez, Source	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)	1110	0.114	0.3998	Yes
28	TMEM45B	TMEM45B Entrez, Source	transmembrane protein 45B	1246	0.108	0.3980	Yes
29	ARG2	ARG2 Entrez, Source	arginase, type II	1251	0.107	0.4060	Yes
30	IER2	IER2 Entrez, Source	immediate early response 2	1295	0.104	0.4109	Yes
31	DUSP1	DUSP1 Entrez, Source	dual specificity phosphatase 1	1297	0.104	0.4190	Yes
32	MMP14	MMP14 Entrez, Source	matrix metallopeptidase 14 (membrane-inserted)	1312	0.104	0.4260	Yes
33	IL13RA2	IL13RA2 Entrez, Source	interleukin 13 receptor, alpha 2	1324	0.103	0.4331	Yes
34	PLAUR	PLAUR Entrez, Source	plasminogen activator, urokinase receptor	1327	0.103	0.4410	Yes
35	EPAS1	EPAS1 Entrez, Source	endothelial PAS domain protein 1	1345	0.102	0.4476	Yes
36	EFNA5	EFNA5 Entrez, Source	ephrin-A5	1436	0.097	0.4483	Yes
37	PVR	PVR Entrez, Source	poliovirus receptor	1458	0.096	0.4542	Yes
38	CXCL1	CXCL1 Entrez, Source	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	1541	0.092	0.4551	Yes
39	ZFP36	ZFP36 Entrez, Source	zinc finger protein 36, C3H type, homolog (mouse)	1543	0.092	0.4622	Yes
40	SERPINB5	SERPINB5 Entrez, Source	serpin peptidase inhibitor, clade B (ovalbumin), member 5	1661	0.086	0.4600	Yes
41	ACOT7	ACOT7 Entrez, Source	acyl-CoA thioesterase 7	1681	0.086	0.4653	Yes
42	PRSS1	PRSS1 Entrez, Source	protease, serine, 1 (trypsin 1)	1721	0.084	0.4688	Yes
43	DKK3	DKK3 Entrez, Source	dickkopf homolog 3 (Xenopus laevis)	1742	0.083	0.4738	Yes
44	CXCL5	CXCL5 Entrez, Source	chemokine (C-X-C motif) ligand 5	1832	0.079	0.4732	No
45	FGFBP1	FGFBP1 Entrez, Source	fibroblast growth factor binding protein 1	2072	0.071	0.4606	No
46	DUSP4	DUSP4 Entrez, Source	dual specificity phosphatase 4	2162	0.068	0.4592	No
47	LRRC8C	LRRC8C Entrez, Source	leucine rich repeat containing 8 family, member C	2210	0.067	0.4608	No
48	CLCF1	CLCF1 Entrez, Source	cardiotrophin-like cytokine factor 1	2268	0.065	0.4616	No
49	HPSE	HPSE Entrez, Source	heparanase	2323	0.064	0.4625	No
50	SLC6A15	SLC6A15 Entrez, Source	solute carrier family 6, member 15	2585	0.058	0.4472	No
51	HIST1H1E	HIST1H1E Entrez, Source	histone cluster 1, H1e	2616	0.057	0.4494	No
52	FN1	FN1 Entrez, Source	fibronectin 1	2637	0.057	0.4523	No
53	TIA1	TIA1 Entrez, Source	TIA1 cytotoxic granule-associated RNA binding protein	2850	0.052	0.4402	No
54	GJB3	GJB3 Entrez, Source	gap junction protein, beta 3, 31kDa (connexin 31)	2912	0.051	0.4395	No
55	EREG	EREG Entrez, Source	epiregulin	2999	0.049	0.4368	No
56	NFIB	NFIB Entrez, Source	nuclear factor I/B	3057	0.047	0.4362	No
57	INPP1	INPP1 Entrez, Source	inositol polyphosphate-1-phosphatase	3079	0.047	0.4383	No
58	SEMA4B	SEMA4B Entrez, Source	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	3091	0.047	0.4411	No
59	SDC4	SDC4 Entrez, Source	syndecan 4 (amphiglycan, ryudocan)	3195	0.045	0.4368	No
60	TIMP1	TIMP1 Entrez, Source	TIMP metallopeptidase inhibitor 1	3256	0.044	0.4356	No
61	EGR1	EGR1 Entrez, Source	early growth response 1	3274	0.043	0.4377	No
62	MAP1LC3B	MAP1LC3B Entrez, Source	microtubule-associated protein 1 light chain 3 beta	3406	0.040	0.4309	No
63	MYD88	MYD88 Entrez, Source	myeloid differentiation primary response gene (88)	3471	0.039	0.4291	No
64	UPP1	UPP1 Entrez, Source	uridine phosphorylase 1	3489	0.039	0.4308	No
65	PTPRE	PTPRE Entrez, Source	protein tyrosine phosphatase, receptor type, E	3646	0.036	0.4218	No
66	SERPINB3	SERPINB3 Entrez, Source	serpin peptidase inhibitor, clade B (ovalbumin), member 3	3724	0.035	0.4187	No
67	TOR1AIP1	TOR1AIP1 Entrez, Source	torsin A interacting protein 1	3771	0.034	0.4179	No
68	EFNB1	EFNB1 Entrez, Source	ephrin-B1	3795	0.034	0.4187	No
69	MBOAT2	MBOAT2 Entrez, Source	membrane bound O-acyltransferase domain containing 2	3842	0.033	0.4178	No
70	CCNA1	CCNA1 Entrez, Source	cyclin A1	3861	0.032	0.4189	No
71	SMTN	SMTN Entrez, Source	smoothelin	3924	0.031	0.4167	No
72	TBX3	TBX3 Entrez, Source	T-box 3 (ulnar mammary syndrome)	3943	0.031	0.4178	No
73	DUSP6	DUSP6 Entrez, Source	dual specificity phosphatase 6	4288	0.026	0.3937	No
74	MCL1	MCL1 Entrez, Source	myeloid cell leukemia sequence 1 (BCL2-related)	4307	0.025	0.3943	No
75	ITPR3	ITPR3 Entrez, Source	inositol 1,4,5-triphosphate receptor, type 3	4344	0.025	0.3935	No
76	COL12A1	COL12A1 Entrez, Source	collagen, type XII, alpha 1	4363	0.024	0.3940	No
77	CSNK1D	CSNK1D Entrez, Source	casein kinase 1, delta	4393	0.024	0.3937	No
78	PTHLH	PTHLH Entrez, Source	parathyroid hormone-like hormone	4594	0.021	0.3802	No
79	CALM2	CALM2 Entrez, Source	calmodulin 2 (phosphorylase kinase, delta)	4699	0.020	0.3738	No
80	STX1A	STX1A Entrez, Source	syntaxin 1A (brain)	4732	0.019	0.3729	No
81	HMGN3	HMGN3 Entrez, Source	high mobility group nucleosomal binding domain 3	5092	0.014	0.3468	No
82	IL1A	IL1A Entrez, Source	interleukin 1, alpha	5162	0.013	0.3426	No
83	ATP2B1	ATP2B1 Entrez, Source	ATPase, Ca++ transporting, plasma membrane 1	5288	0.011	0.3340	No
84	DLL1	DLL1 Entrez, Source	delta-like 1 (Drosophila)	5403	0.010	0.3261	No
85	FBXO9	FBXO9 Entrez, Source	F-box protein 9	5615	0.007	0.3107	No
86	PPBP	PPBP Entrez, Source	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	5643	0.006	0.3091	No
87	CSNK1E	CSNK1E Entrez, Source	casein kinase 1, epsilon	5823	0.004	0.2959	No
88	IRX2	IRX2 Entrez, Source	iroquois homeobox protein 2	5837	0.004	0.2952	No
89	PPIF	PPIF Entrez, Source	peptidylprolyl isomerase F (cyclophilin F)	5913	0.003	0.2898	No
90	TPM1	TPM1 Entrez, Source	tropomyosin 1 (alpha)	5926	0.003	0.2891	No
91	ODC1	ODC1 Entrez, Source	ornithine decarboxylase 1	5974	0.002	0.2857	No
92	TOP1	TOP1 Entrez, Source	topoisomerase (DNA) I	6189	-0.000	0.2696	No
93	MALL	MALL Entrez, Source	mal, T-cell differentiation protein-like	6400	-0.003	0.2539	No
94	LAMA3	LAMA3 Entrez, Source	laminin, alpha 3	6404	-0.003	0.2539	No
95	LDLR	LDLR Entrez, Source	low density lipoprotein receptor (familial hypercholesterolemia)	6572	-0.005	0.2417	No
96	EHD1	EHD1 Entrez, Source	EH-domain containing 1	6660	-0.007	0.2356	No
97	TFPI2	TFPI2 Entrez, Source	tissue factor pathway inhibitor 2	6771	-0.008	0.2279	No
98	ARHGAP27	ARHGAP27 Entrez, Source	Rho GTPase activating protein 27	6907	-0.010	0.2184	No
99	NDRG1	NDRG1 Entrez, Source	N-myc downstream regulated gene 1	6962	-0.010	0.2151	No
100	CASP1	CASP1 Entrez, Source	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	7177	-0.013	0.1999	No
101	TGFA	TGFA Entrez, Source	transforming growth factor, alpha	7317	-0.014	0.1905	No
102	AKAP12	AKAP12 Entrez, Source	A kinase (PRKA) anchor protein (gravin) 12	7409	-0.015	0.1848	No
103	MTUS1	MTUS1 Entrez, Source	mitochondrial tumor suppressor 1	7445	-0.016	0.1834	No
104	KCNK1	KCNK1 Entrez, Source	potassium channel, subfamily K, member 1	7542	-0.017	0.1775	No
105	HRAS	HRAS Entrez, Source	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	7568	-0.018	0.1770	No
106	HK2	HK2 Entrez, Source	hexokinase 2	7823	-0.021	0.1594	No
107	FOSL1	FOSL1 Entrez, Source	FOS-like antigen 1	8279	-0.028	0.1270	No
108	TOB1	TOB1 Entrez, Source	transducer of ERBB2, 1	8322	-0.028	0.1260	No
109	SERPINB2	SERPINB2 Entrez, Source	serpin peptidase inhibitor, clade B (ovalbumin), member 2	8340	-0.028	0.1270	No
110	SDC1	SDC1 Entrez, Source	syndecan 1	8470	-0.031	0.1196	No
111	FLNB	FLNB Entrez, Source	filamin B, beta (actin binding protein 278)	8603	-0.032	0.1121	No
112	SOCS1	SOCS1 Entrez, Source	suppressor of cytokine signaling 1	8877	-0.036	0.0942	No
113	MDH1	MDH1 Entrez, Source	malate dehydrogenase 1, NAD (soluble)	9065	-0.038	0.0830	No
114	MID1	MID1 Entrez, Source	midline 1 (Opitz/BBB syndrome)	9243	-0.041	0.0728	No
115	TSC22D1	TSC22D1 Entrez, Source	TSC22 domain family, member 1	9967	-0.053	0.0221	No
116	SLC2A3	SLC2A3 Entrez, Source	solute carrier family 2 (facilitated glucose transporter), member 3	9985	-0.053	0.0250	No
117	IL11	IL11 Entrez, Source	interleukin 11	10189	-0.057	0.0140	No
118	PTGS2	PTGS2 Entrez, Source	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	10192	-0.057	0.0183	No
119	TNS4	TNS4 Entrez, Source	tensin 4	10200	-0.057	0.0222	No
120	ARHGEF9	ARHGEF9 Entrez, Source	Cdc42 guanine nucleotide exchange factor (GEF) 9	10203	-0.057	0.0264	No
121	PBEF1	PBEF1 Entrez, Source	pre-B-cell colony enhancing factor 1	10279	-0.058	0.0253	No
122	VEGF	VEGF Entrez, Source	vascular endothelial growth factor	10686	-0.066	-0.0003	No
123	DDX17	DDX17 Entrez, Source	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	10688	-0.066	0.0047	No
124	LGALS8	LGALS8 Entrez, Source	lectin, galactoside-binding, soluble, 8 (galectin 8)	10732	-0.067	0.0067	No
125	CYP27B1	CYP27B1 Entrez, Source	cytochrome P450, family 27, subfamily B, polypeptide 1	10795	-0.068	0.0073	No
126	SAMD8	SAMD8 Entrez, Source	sterile alpha motif domain containing 8	10922	-0.071	0.0033	No
127	CYP1B1	CYP1B1 Entrez, Source	cytochrome P450, family 1, subfamily B, polypeptide 1	10964	-0.073	0.0058	No
128	RUNX1	RUNX1 Entrez, Source	runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)	11134	-0.077	-0.0010	No
129	NT5E	NT5E Entrez, Source	5'-nucleotidase, ecto (CD73)	11299	-0.081	-0.0071	No
130	SLC9A1	SLC9A1 Entrez, Source	solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive)	11386	-0.084	-0.0071	No
131	KCNN4	KCNN4 Entrez, Source	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	11462	-0.085	-0.0061	No
132	PIM1	PIM1 Entrez, Source	pim-1 oncogene	11624	-0.090	-0.0113	No
133	FOXQ1	FOXQ1 Entrez, Source	forkhead box Q1	11748	-0.094	-0.0134	No
134	HNRPH1	HNRPH1 Entrez, Source	heterogeneous nuclear ribonucleoprotein H1 (H)	12186	-0.111	-0.0378	No
135	CASP2	CASP2 Entrez, Source	caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2)	12210	-0.112	-0.0309	No
136	LYN	LYN Entrez, Source	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	12283	-0.115	-0.0273	No
137	NOLC1	NOLC1 Entrez, Source	nucleolar and coiled-body phosphoprotein 1	12447	-0.123	-0.0301	No
138	GTPBP2	GTPBP2 Entrez, Source	GTP binding protein 2	12459	-0.124	-0.0213	No
139	ADRB2	ADRB2 Entrez, Source	adrenergic, beta-2-, receptor, surface	12708	-0.142	-0.0290	No
140	COL27A1	COL27A1 Entrez, Source	collagen, type XXVII, alpha 1	12813	-0.154	-0.0248	No
141	FGFR2	FGFR2 Entrez, Source	ffer syndrome, Jackson-Weiss syndrome)	13200	-0.255	-0.0343	No
142	G0S2	G0S2 Entrez, Source	G0/G1switch 2	13227	-0.274	-0.0149	No
143	ABCA1	ABCA1 Entrez, Source	ATP-binding cassette, sub-family A (ABC1), member 1	13254	-0.302	0.0067	No