Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY |
| Enrichment Score (ES) | 0.80220896 |
| Normalized Enrichment Score (NES) | 2.1088817 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0020660788 |
| FWER p-Value | 0.027 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RAMP1 | RAMP1 Entrez, Source | receptor (calcitonin) activity modifying protein 1 | 37 | 0.635 | 0.1816 | Yes |
| 2 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 42 | 0.616 | 0.3601 | Yes |
| 3 | PLCE1 | PLCE1 Entrez, Source | phospholipase C, epsilon 1 | 114 | 0.408 | 0.4732 | Yes |
| 4 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 126 | 0.391 | 0.5861 | Yes |
| 5 | RGS4 | RGS4 Entrez, Source | regulator of G-protein signalling 4 | 219 | 0.308 | 0.6686 | Yes |
| 6 | RGS5 | RGS5 Entrez, Source | regulator of G-protein signalling 5 | 306 | 0.247 | 0.7338 | Yes |
| 7 | GRK5 | GRK5 Entrez, Source | G protein-coupled receptor kinase 5 | 401 | 0.209 | 0.7875 | Yes |
| 8 | RGS3 | RGS3 Entrez, Source | regulator of G-protein signalling 3 | 762 | 0.144 | 0.8022 | Yes |
| 9 | RIC8B | RIC8B Entrez, Source | resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) | 1253 | 0.107 | 0.7966 | No |
| 10 | ADRB3 | ADRB3 Entrez, Source | adrenergic, beta-3-, receptor | 2242 | 0.066 | 0.7416 | No |
| 11 | GIT1 | GIT1 Entrez, Source | G protein-coupled receptor kinase interactor 1 | 2932 | 0.050 | 0.7045 | No |
| 12 | GRK1 | GRK1 Entrez, Source | G protein-coupled receptor kinase 1 | 3340 | 0.042 | 0.6860 | No |
| 13 | GNG7 | GNG7 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 7 | 4525 | 0.022 | 0.6036 | No |
| 14 | RGS12 | RGS12 Entrez, Source | regulator of G-protein signalling 12 | 4561 | 0.022 | 0.6072 | No |
| 15 | GRK4 | GRK4 Entrez, Source | G protein-coupled receptor kinase 4 | 5401 | 0.010 | 0.5470 | No |
| 16 | GIT2 | GIT2 Entrez, Source | G protein-coupled receptor kinase interactor 2 | 6006 | 0.002 | 0.5023 | No |
| 17 | RGS9 | RGS9 Entrez, Source | regulator of G-protein signalling 9 | 6017 | 0.002 | 0.5021 | No |
| 18 | RGS14 | RGS14 Entrez, Source | regulator of G-protein signalling 14 | 6865 | -0.009 | 0.4412 | No |
| 19 | GRK6 | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 7131 | -0.012 | 0.4248 | No |
| 20 | ADRB2 | ADRB2 Entrez, Source | adrenergic, beta-2-, receptor, surface | 12708 | -0.142 | 0.0476 | No |
