Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | REN_E2F1_TARGETS |
| Enrichment Score (ES) | -0.40642735 |
| Normalized Enrichment Score (NES) | -1.2031226 |
| Nominal p-value | 0.24295011 |
| FDR q-value | 0.6509024 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 1021 | 0.119 | 0.0027 | No |
| 2 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 2181 | 0.068 | -0.0393 | No |
| 3 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 3405 | 0.040 | -0.1043 | No |
| 4 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 3568 | 0.037 | -0.0917 | No |
| 5 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 3593 | 0.037 | -0.0689 | No |
| 6 | CALM2 | CALM2 Entrez, Source | calmodulin 2 (phosphorylase kinase, delta) | 4699 | 0.020 | -0.1389 | No |
| 7 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 5938 | 0.003 | -0.2299 | No |
| 8 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 7715 | -0.020 | -0.3502 | No |
| 9 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8111 | -0.025 | -0.3632 | No |
| 10 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 8535 | -0.031 | -0.3742 | Yes |
| 11 | CALR | CALR Entrez, Source | calreticulin | 8727 | -0.034 | -0.3660 | Yes |
| 12 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 8780 | -0.035 | -0.3470 | Yes |
| 13 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9154 | -0.040 | -0.3487 | Yes |
| 14 | NCL | NCL Entrez, Source | nucleolin | 9448 | -0.044 | -0.3413 | Yes |
| 15 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 9651 | -0.048 | -0.3247 | Yes |
| 16 | PRPSAP1 | PRPSAP1 Entrez, Source | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 10740 | -0.067 | -0.3619 | Yes |
| 17 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 10979 | -0.073 | -0.3315 | Yes |
| 18 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 11274 | -0.081 | -0.3001 | Yes |
| 19 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 11282 | -0.081 | -0.2469 | Yes |
| 20 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 11707 | -0.092 | -0.2175 | Yes |
| 21 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12418 | -0.122 | -0.1897 | Yes |
| 22 | SLC3A2 | SLC3A2 Entrez, Source | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 13019 | -0.189 | -0.1092 | Yes |
| 23 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 13067 | -0.201 | 0.0206 | Yes |
