Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY |
| Enrichment Score (ES) | -0.5328909 |
| Normalized Enrichment Score (NES) | -1.7026962 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.18327454 |
| FWER p-Value | 0.998 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EIF2B2 | EIF2B2 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa | 924 | 0.127 | -0.0180 | No |
| 2 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 1084 | 0.116 | 0.0169 | No |
| 3 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 3810 | 0.033 | -0.1744 | No |
| 4 | EIF5 | EIF5 Entrez, Source | eukaryotic translation initiation factor 5 | 4315 | 0.025 | -0.2021 | No |
| 5 | EIF4A2 | EIF4A2 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 2 | 4806 | 0.018 | -0.2315 | No |
| 6 | SLU7 | SLU7 Entrez, Source | - | 4976 | 0.016 | -0.2380 | No |
| 7 | EIF2B1 | EIF2B1 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | 5340 | 0.011 | -0.2610 | No |
| 8 | EIF2AK3 | EIF2AK3 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 3 | 5437 | 0.009 | -0.2645 | No |
| 9 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 6720 | -0.007 | -0.3578 | No |
| 10 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 7120 | -0.012 | -0.3829 | No |
| 11 | SF3A2 | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 7150 | -0.012 | -0.3801 | No |
| 12 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 7205 | -0.013 | -0.3788 | No |
| 13 | POP4 | POP4 Entrez, Source | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) | 7679 | -0.019 | -0.4066 | No |
| 14 | EIF4G2 | EIF4G2 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 2 | 8447 | -0.030 | -0.4521 | No |
| 15 | EIF2B4 | EIF2B4 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 8566 | -0.032 | -0.4481 | No |
| 16 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 8947 | -0.037 | -0.4617 | No |
| 17 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 9386 | -0.043 | -0.4771 | No |
| 18 | EIF2B3 | EIF2B3 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa | 10129 | -0.056 | -0.5104 | Yes |
| 19 | GEMIN6 | GEMIN6 Entrez, Source | gem (nuclear organelle) associated protein 6 | 10170 | -0.056 | -0.4906 | Yes |
| 20 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 10205 | -0.057 | -0.4701 | Yes |
| 21 | RPS3A | RPS3A Entrez, Source | ribosomal protein S3A | 10285 | -0.058 | -0.4525 | Yes |
| 22 | CRNKL1 | CRNKL1 Entrez, Source | Crn, crooked neck-like 1 (Drosophila) | 10445 | -0.061 | -0.4397 | Yes |
| 23 | FBL | FBL Entrez, Source | fibrillarin | 10535 | -0.063 | -0.4209 | Yes |
| 24 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 10861 | -0.070 | -0.4170 | Yes |
| 25 | DDX20 | DDX20 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 11083 | -0.075 | -0.4031 | Yes |
| 26 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 11090 | -0.075 | -0.3730 | Yes |
| 27 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 11513 | -0.087 | -0.3696 | Yes |
| 28 | MTIF2 | MTIF2 Entrez, Source | mitochondrial translational initiation factor 2 | 11529 | -0.087 | -0.3353 | Yes |
| 29 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 11660 | -0.090 | -0.3085 | Yes |
| 30 | EIF1 | EIF1 Entrez, Source | eukaryotic translation initiation factor 1 | 11741 | -0.093 | -0.2767 | Yes |
| 31 | NOL5A | NOL5A Entrez, Source | nucleolar protein 5A (56kDa with KKE/D repeat) | 11821 | -0.096 | -0.2436 | Yes |
| 32 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 11902 | -0.099 | -0.2094 | Yes |
| 33 | EIF2B5 | EIF2B5 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa | 12127 | -0.108 | -0.1824 | Yes |
| 34 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12447 | -0.123 | -0.1563 | Yes |
| 35 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12532 | -0.130 | -0.1100 | Yes |
| 36 | SDAD1 | SDAD1 Entrez, Source | SDA1 domain containing 1 | 13043 | -0.196 | -0.0689 | Yes |
| 37 | DICER1 | DICER1 Entrez, Source | Dicer1, Dcr-1 homolog (Drosophila) | 13152 | -0.225 | 0.0143 | Yes |
