Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | RNA_BINDING |
| Enrichment Score (ES) | -0.46457022 |
| Normalized Enrichment Score (NES) | -1.9213985 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.06510868 |
| FWER p-Value | 0.425 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 325 | 0.238 | -0.0017 | No |
| 2 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 561 | 0.171 | -0.0030 | No |
| 3 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 832 | 0.136 | -0.0103 | No |
| 4 | ROD1 | ROD1 Entrez, Source | ROD1 regulator of differentiation 1 (S. pombe) | 942 | 0.126 | -0.0065 | No |
| 5 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 977 | 0.123 | 0.0029 | No |
| 6 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1068 | 0.116 | 0.0073 | No |
| 7 | IREB2 | IREB2 Entrez, Source | iron-responsive element binding protein 2 | 1211 | 0.109 | 0.0070 | No |
| 8 | ZFP36L1 | ZFP36L1 Entrez, Source | zinc finger protein 36, C3H type-like 1 | 1350 | 0.101 | 0.0063 | No |
| 9 | ZFP36 | ZFP36 Entrez, Source | zinc finger protein 36, C3H type, homolog (mouse) | 1543 | 0.092 | 0.0006 | No |
| 10 | HNRPA3 | HNRPA3 Entrez, Source | heterogeneous nuclear ribonucleoprotein A3 | 1631 | 0.088 | 0.0025 | No |
| 11 | FARS2 | FARS2 Entrez, Source | phenylalanine-tRNA synthetase 2 (mitochondrial) | 1738 | 0.083 | 0.0025 | No |
| 12 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 2178 | 0.068 | -0.0242 | No |
| 13 | ATXN1 | ATXN1 Entrez, Source | ataxin 1 | 2254 | 0.066 | -0.0236 | No |
| 14 | TIA1 | TIA1 Entrez, Source | TIA1 cytotoxic granule-associated RNA binding protein | 2850 | 0.052 | -0.0637 | No |
| 15 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 3538 | 0.038 | -0.1120 | No |
| 16 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 3618 | 0.037 | -0.1145 | No |
| 17 | PSMA1 | PSMA1 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 1 | 4225 | 0.027 | -0.1578 | No |
| 18 | STAU2 | STAU2 Entrez, Source | staufen, RNA binding protein, homolog 2 (Drosophila) | 4691 | 0.020 | -0.1911 | No |
| 19 | DDX19B | DDX19B Entrez, Source | DEAD (Asp-Glu-Ala-As) box polypeptide 19B | 4858 | 0.017 | -0.2020 | No |
| 20 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 4901 | 0.017 | -0.2036 | No |
| 21 | SLU7 | SLU7 Entrez, Source | - | 4976 | 0.016 | -0.2077 | No |
| 22 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 5091 | 0.014 | -0.2150 | No |
| 23 | TRNT1 | TRNT1 Entrez, Source | tRNA nucleotidyl transferase, CCA-adding, 1 | 5151 | 0.013 | -0.2182 | No |
| 24 | CUGBP2 | CUGBP2 Entrez, Source | CUG triplet repeat, RNA binding protein 2 | 5461 | 0.009 | -0.2407 | No |
| 25 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 5567 | 0.007 | -0.2480 | No |
| 26 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 5830 | 0.004 | -0.2674 | No |
| 27 | RTCD1 | RTCD1 Entrez, Source | RNA terminal phosphate cyclase domain 1 | 5993 | 0.002 | -0.2795 | No |
| 28 | RBMS2 | RBMS2 Entrez, Source | RNA binding motif, single stranded interacting protein 2 | 6058 | 0.001 | -0.2842 | No |
| 29 | NR0B1 | NR0B1 Entrez, Source | nuclear receptor subfamily 0, group B, member 1 | 6385 | -0.003 | -0.3086 | No |
| 30 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 6720 | -0.007 | -0.3332 | No |
| 31 | RPL9 | RPL9 Entrez, Source | ribosomal protein L9 | 7187 | -0.013 | -0.3673 | No |
| 32 | CIRBP | CIRBP Entrez, Source | cold inducible RNA binding protein | 7213 | -0.013 | -0.3679 | No |
| 33 | GRSF1 | GRSF1 Entrez, Source | G-rich RNA sequence binding factor 1 | 7484 | -0.016 | -0.3867 | No |
| 34 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 7584 | -0.018 | -0.3925 | No |
| 35 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 7633 | -0.019 | -0.3944 | No |
| 36 | POP4 | POP4 Entrez, Source | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) | 7679 | -0.019 | -0.3959 | No |
| 37 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 8090 | -0.025 | -0.4246 | No |
| 38 | MRPS7 | MRPS7 Entrez, Source | mitochondrial ribosomal protein S7 | 8162 | -0.026 | -0.4274 | No |
| 39 | RPS6 | RPS6 Entrez, Source | ribosomal protein S6 | 8195 | -0.026 | -0.4273 | No |
| 40 | STAU1 | STAU1 Entrez, Source | staufen, RNA binding protein, homolog 1 (Drosophila) | 8255 | -0.027 | -0.4292 | No |
| 41 | HNRPK | HNRPK Entrez, Source | heterogeneous nuclear ribonucleoprotein K | 8260 | -0.027 | -0.4268 | No |
| 42 | EIF2S2 | EIF2S2 Entrez, Source | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 8326 | -0.028 | -0.4290 | No |
| 43 | RPL26 | RPL26 Entrez, Source | ribosomal protein L26 | 8372 | -0.029 | -0.4297 | No |
| 44 | TARBP2 | TARBP2 Entrez, Source | Tar (HIV-1) RNA binding protein 2 | 8450 | -0.030 | -0.4326 | No |
| 45 | RNASEH1 | RNASEH1 Entrez, Source | ribonuclease H1 | 8474 | -0.031 | -0.4314 | No |
| 46 | DUSP11 | DUSP11 Entrez, Source | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 8581 | -0.032 | -0.4363 | No |
| 47 | RPS29 | RPS29 Entrez, Source | ribosomal protein S29 | 8679 | -0.033 | -0.4405 | No |
| 48 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 8696 | -0.034 | -0.4384 | No |
| 49 | RPL41 | RPL41 Entrez, Source | ribosomal protein L41 | 8782 | -0.035 | -0.4415 | No |
| 50 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 8947 | -0.037 | -0.4504 | No |
| 51 | SERBP1 | SERBP1 Entrez, Source | SERPINE1 mRNA binding protein 1 | 8948 | -0.037 | -0.4468 | No |
| 52 | RPL19 | RPL19 Entrez, Source | ribosomal protein L19 | 8959 | -0.037 | -0.4440 | No |
| 53 | EIF4A1 | EIF4A1 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 1 | 9007 | -0.038 | -0.4440 | No |
| 54 | PABPN1 | PABPN1 Entrez, Source | poly(A) binding protein, nuclear 1 | 9064 | -0.038 | -0.4445 | No |
| 55 | RNASEL | RNASEL Entrez, Source | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) | 9080 | -0.039 | -0.4419 | No |
| 56 | HNRPAB | HNRPAB Entrez, Source | heterogeneous nuclear ribonucleoprotein A/B | 9101 | -0.039 | -0.4397 | No |
| 57 | RPS17 | RPS17 Entrez, Source | ribosomal protein S17 | 9118 | -0.039 | -0.4371 | No |
| 58 | RPL3 | RPL3 Entrez, Source | ribosomal protein L3 | 9257 | -0.041 | -0.4436 | No |
| 59 | RAE1 | RAE1 Entrez, Source | RAE1 RNA export 1 homolog (S. pombe) | 9329 | -0.042 | -0.4449 | No |
| 60 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 9386 | -0.043 | -0.4450 | No |
| 61 | NCL | NCL Entrez, Source | nucleolin | 9448 | -0.044 | -0.4454 | No |
| 62 | RBM5 | RBM5 Entrez, Source | RNA binding motif protein 5 | 9487 | -0.045 | -0.4439 | No |
| 63 | MRPL12 | MRPL12 Entrez, Source | mitochondrial ribosomal protein L12 | 9628 | -0.047 | -0.4500 | No |
| 64 | RPL4 | RPL4 Entrez, Source | ribosomal protein L4 | 9822 | -0.051 | -0.4597 | Yes |
| 65 | PPIE | PPIE Entrez, Source | peptidylprolyl isomerase E (cyclophilin E) | 9839 | -0.051 | -0.4560 | Yes |
| 66 | RPL6 | RPL6 Entrez, Source | ribosomal protein L6 | 9882 | -0.052 | -0.4542 | Yes |
| 67 | RPLP1 | RPLP1 Entrez, Source | ribosomal protein, large, P1 | 9958 | -0.053 | -0.4548 | Yes |
| 68 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 10069 | -0.055 | -0.4579 | Yes |
| 69 | RPL29 | RPL29 Entrez, Source | ribosomal protein L29 | 10090 | -0.055 | -0.4541 | Yes |
| 70 | RPS15A | RPS15A Entrez, Source | ribosomal protein S15a | 10118 | -0.055 | -0.4508 | Yes |
| 71 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 10123 | -0.056 | -0.4457 | Yes |
| 72 | RPL31 | RPL31 Entrez, Source | ribosomal protein L31 | 10162 | -0.056 | -0.4432 | Yes |
| 73 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 10205 | -0.057 | -0.4409 | Yes |
| 74 | RPS3A | RPS3A Entrez, Source | ribosomal protein S3A | 10285 | -0.058 | -0.4413 | Yes |
| 75 | RPS8 | RPS8 Entrez, Source | ribosomal protein S8 | 10302 | -0.058 | -0.4368 | Yes |
| 76 | RPS13 | RPS13 Entrez, Source | ribosomal protein S13 | 10363 | -0.059 | -0.4356 | Yes |
| 77 | RPS21 | RPS21 Entrez, Source | ribosomal protein S21 | 10407 | -0.060 | -0.4331 | Yes |
| 78 | EWSR1 | EWSR1 Entrez, Source | Ewing sarcoma breakpoint region 1 | 10419 | -0.061 | -0.4281 | Yes |
| 79 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 10434 | -0.061 | -0.4233 | Yes |
| 80 | FBL | FBL Entrez, Source | fibrillarin | 10535 | -0.063 | -0.4248 | Yes |
| 81 | RPL18 | RPL18 Entrez, Source | ribosomal protein L18 | 10558 | -0.063 | -0.4203 | Yes |
| 82 | PRPF8 | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 10586 | -0.064 | -0.4162 | Yes |
| 83 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10688 | -0.066 | -0.4175 | Yes |
| 84 | RPS26 | RPS26 Entrez, Source | ribosomal protein S26 | 10735 | -0.067 | -0.4145 | Yes |
| 85 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 10794 | -0.068 | -0.4123 | Yes |
| 86 | RPS10 | RPS10 Entrez, Source | ribosomal protein S10 | 10808 | -0.069 | -0.4067 | Yes |
| 87 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 10861 | -0.070 | -0.4039 | Yes |
| 88 | RPL15 | RPL15 Entrez, Source | ribosomal protein L15 | 10874 | -0.070 | -0.3980 | Yes |
| 89 | RPS23 | RPS23 Entrez, Source | ribosomal protein S23 | 10900 | -0.071 | -0.3931 | Yes |
| 90 | MKI67IP | MKI67IP Entrez, Source | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 10951 | -0.072 | -0.3899 | Yes |
| 91 | RPL28 | RPL28 Entrez, Source | ribosomal protein L28 | 10952 | -0.072 | -0.3829 | Yes |
| 92 | ADARB2 | ADARB2 Entrez, Source | adenosine deaminase, RNA-specific, B2 (RED2 homolog rat) | 10977 | -0.073 | -0.3777 | Yes |
| 93 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 10990 | -0.073 | -0.3716 | Yes |
| 94 | SSB | SSB Entrez, Source | Sjogren syndrome antigen B (autoantigen La) | 10994 | -0.073 | -0.3648 | Yes |
| 95 | NUFIP1 | NUFIP1 Entrez, Source | nuclear fragile X mental retardation protein interacting protein 1 | 11003 | -0.073 | -0.3583 | Yes |
| 96 | RPL7 | RPL7 Entrez, Source | ribosomal protein L7 | 11020 | -0.074 | -0.3524 | Yes |
| 97 | AKAP1 | AKAP1 Entrez, Source | A kinase (PRKA) anchor protein 1 | 11031 | -0.074 | -0.3460 | Yes |
| 98 | RPL30 | RPL30 Entrez, Source | ribosomal protein L30 | 11059 | -0.075 | -0.3409 | Yes |
| 99 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 11090 | -0.075 | -0.3359 | Yes |
| 100 | SCYE1 | SCYE1 Entrez, Source | small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) | 11138 | -0.077 | -0.3320 | Yes |
| 101 | RPS24 | RPS24 Entrez, Source | ribosomal protein S24 | 11160 | -0.077 | -0.3262 | Yes |
| 102 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 11203 | -0.078 | -0.3218 | Yes |
| 103 | RPS5 | RPS5 Entrez, Source | ribosomal protein S5 | 11241 | -0.080 | -0.3169 | Yes |
| 104 | RPS27 | RPS27 Entrez, Source | ribosomal protein S27 (metallopanstimulin 1) | 11258 | -0.080 | -0.3104 | Yes |
| 105 | MRPL23 | MRPL23 Entrez, Source | mitochondrial ribosomal protein L23 | 11272 | -0.081 | -0.3036 | Yes |
| 106 | RPL21 | RPL21 Entrez, Source | ribosomal protein L21 | 11315 | -0.082 | -0.2989 | Yes |
| 107 | PCBP2 | PCBP2 Entrez, Source | poly(rC) binding protein 2 | 11317 | -0.082 | -0.2911 | Yes |
| 108 | TEP1 | TEP1 Entrez, Source | telomerase-associated protein 1 | 11364 | -0.083 | -0.2866 | Yes |
| 109 | RPL13 | RPL13 Entrez, Source | ribosomal protein L13 | 11394 | -0.084 | -0.2807 | Yes |
| 110 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 11513 | -0.087 | -0.2813 | Yes |
| 111 | RPS3 | RPS3 Entrez, Source | ribosomal protein S3 | 11521 | -0.087 | -0.2734 | Yes |
| 112 | RPL24 | RPL24 Entrez, Source | ribosomal protein L24 | 11552 | -0.088 | -0.2672 | Yes |
| 113 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 11660 | -0.090 | -0.2666 | Yes |
| 114 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 11682 | -0.091 | -0.2594 | Yes |
| 115 | RPS12 | RPS12 Entrez, Source | ribosomal protein S12 | 11705 | -0.092 | -0.2521 | Yes |
| 116 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 11763 | -0.094 | -0.2474 | Yes |
| 117 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 11792 | -0.095 | -0.2403 | Yes |
| 118 | NOL5A | NOL5A Entrez, Source | nucleolar protein 5A (56kDa with KKE/D repeat) | 11821 | -0.096 | -0.2332 | Yes |
| 119 | RPL35 | RPL35 Entrez, Source | ribosomal protein L35 | 11865 | -0.098 | -0.2270 | Yes |
| 120 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 11902 | -0.099 | -0.2201 | Yes |
| 121 | CSTF1 | CSTF1 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 11951 | -0.101 | -0.2140 | Yes |
| 122 | HNRPF | HNRPF Entrez, Source | heterogeneous nuclear ribonucleoprotein F | 11999 | -0.103 | -0.2076 | Yes |
| 123 | RPL22 | RPL22 Entrez, Source | ribosomal protein L22 | 12075 | -0.106 | -0.2031 | Yes |
| 124 | RPL14 | RPL14 Entrez, Source | ribosomal protein L14 | 12085 | -0.107 | -0.1935 | Yes |
| 125 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12122 | -0.108 | -0.1858 | Yes |
| 126 | ETF1 | ETF1 Entrez, Source | eukaryotic translation termination factor 1 | 12179 | -0.110 | -0.1794 | Yes |
| 127 | HNRPH1 | HNRPH1 Entrez, Source | heterogeneous nuclear ribonucleoprotein H1 (H) | 12186 | -0.111 | -0.1692 | Yes |
| 128 | FUS | FUS Entrez, Source | fusion (involved in t(12;16) in malignant liposarcoma) | 12205 | -0.112 | -0.1598 | Yes |
| 129 | SUPV3L1 | SUPV3L1 Entrez, Source | suppressor of var1, 3-like 1 (S. cerevisiae) | 12423 | -0.123 | -0.1644 | Yes |
| 130 | PABPC4 | PABPC4 Entrez, Source | poly(A) binding protein, cytoplasmic 4 (inducible form) | 12431 | -0.123 | -0.1531 | Yes |
| 131 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 12470 | -0.125 | -0.1438 | Yes |
| 132 | RBM3 | RBM3 Entrez, Source | RNA binding motif (RNP1, RRM) protein 3 | 12503 | -0.128 | -0.1339 | Yes |
| 133 | RPS25 | RPS25 Entrez, Source | ribosomal protein S25 | 12514 | -0.129 | -0.1222 | Yes |
| 134 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12532 | -0.130 | -0.1110 | Yes |
| 135 | SNUPN | SNUPN Entrez, Source | snurportin 1 | 12641 | -0.137 | -0.1059 | Yes |
| 136 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12652 | -0.138 | -0.0934 | Yes |
| 137 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 12694 | -0.141 | -0.0829 | Yes |
| 138 | RPL39 | RPL39 Entrez, Source | ribosomal protein L39 | 13115 | -0.215 | -0.0940 | Yes |
| 139 | DAZAP1 | DAZAP1 Entrez, Source | DAZ associated protein 1 | 13125 | -0.217 | -0.0738 | Yes |
| 140 | DICER1 | DICER1 Entrez, Source | Dicer1, Dcr-1 homolog (Drosophila) | 13152 | -0.225 | -0.0540 | Yes |
| 141 | APTX | APTX Entrez, Source | aprataxin | 13219 | -0.270 | -0.0329 | Yes |
| 142 | APOBEC1 | APOBEC1 Entrez, Source | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 | 13309 | -0.437 | 0.0025 | Yes |
